Lu Zhao1, Fengtan Li1, Zewei Zhang1, Zhang Zhang1, Yingjian Jiang1, Xinyu Wang1, Jun Gu2, Dong Li3. 1. Department of Radiology, Tianjin Medical University General Hospital, Tianjin, 300052, China. 2. Siemens Healthineers, Beijing, 100102, China. 3. Department of Radiology, Tianjin Medical University General Hospital, Tianjin, 300052, China. dr_lidong@163.com.
Abstract
OBJECTIVES: To investigate the feasibility of low-concentration contrast media (LC-CM) in cerebral and cervical dual-energy CT angiography (DE-CTA) using an advanced monoenergetic (Mono+) reconstruction technique. METHODS:Sixty-five consecutive patients prospectively selected to undergo cerebral and cervical DE-CTA were randomised into two groups: 32 patients (63.7 ± 9.7 years) in thehigh-concentration contrast medium (HC-CM) group with iopromide370 and 33 patients (60.7 ± 10.8 years) in thelow-concentration contrast medium (LC-CM) group with iodixanol 270. Traditional monoenergetic (Mono) and Mono+ images from 40 to 100 keV levels (at 10-keV intervals) and the standard mixed (Mixed, 120 kVp equivalent) images were reconstructed. Subjective image quality parameters included the contrast-to-noise ratio (CNR) and objective image quality parameters were evaluated and compared between the two groups. RESULTS: The 40-keV Mono+ images in the LC-CM group showed comparable objective CNR (common carotid arteries: 83.7 ± 24.5 vs. 78.1 ± 23.2; internal carotid arteries: 82.2 ± 26.8 vs. 76.8 ± 24.1; middle cerebral arteries: 72.5 ± 24.6 vs. 70.6 ± 19.2; all p > 0.05) and subjective image scores (3.95 ± 0.19 vs. 3.83 ± 0.35; p > 0.05) compared with Mixed images in the HC-CM group. CONCLUSION: The Mono+ reconstruction technique could reduce the concentration of iodinated CM in the diagnosis of cerebral and cervical angiography. KEY POINTS: • Mono+ shows decreased noise and superior CNR compared with Mono. • The 40-keV Mono+ images show the highest CNR in the LC-CM group. • The Mono+ reconstruction technique could reduce the concentration of iodinated CM.
RCT Entities:
OBJECTIVES: To investigate the feasibility of low-concentration contrast media (LC-CM) in cerebral and cervical dual-energy CT angiography (DE-CTA) using an advanced monoenergetic (Mono+) reconstruction technique. METHODS: Sixty-five consecutive patients prospectively selected to undergo cerebral and cervical DE-CTA were randomised into two groups: 32 patients (63.7 ± 9.7 years) in the high-concentration contrast medium (HC-CM) group with iopromide 370 and 33 patients (60.7 ± 10.8 years) in the low-concentration contrast medium (LC-CM) group with iodixanol 270. Traditional monoenergetic (Mono) and Mono+ images from 40 to 100 keV levels (at 10-keV intervals) and the standard mixed (Mixed, 120 kVp equivalent) images were reconstructed. Subjective image quality parameters included the contrast-to-noise ratio (CNR) and objective image quality parameters were evaluated and compared between the two groups. RESULTS: The 40-keV Mono+ images in the LC-CM group showed comparable objective CNR (common carotid arteries: 83.7 ± 24.5 vs. 78.1 ± 23.2; internal carotid arteries: 82.2 ± 26.8 vs. 76.8 ± 24.1; middle cerebral arteries: 72.5 ± 24.6 vs. 70.6 ± 19.2; all p > 0.05) and subjective image scores (3.95 ± 0.19 vs. 3.83 ± 0.35; p > 0.05) compared with Mixed images in the HC-CM group. CONCLUSION: The Mono+ reconstruction technique could reduce the concentration of iodinated CM in the diagnosis of cerebral and cervical angiography. KEY POINTS: • Mono+ shows decreased noise and superior CNR compared with Mono. • The 40-keV Mono+ images show the highest CNR in the LC-CM group. • The Mono+ reconstruction technique could reduce the concentration of iodinated CM.
Authors: Martin Beeres; Jesko Trommer; Claudia Frellesen; Nour-Eldin A Nour-Eldin; Jan E Scholtz; Eva Herrmann; Thomas J Vogl; Julian L Wichmann Journal: Int J Cardiovasc Imaging Date: 2015-08-02 Impact factor: 2.357
Authors: Simon S Martin; Julian L Wichmann; Hendrik Weyer; Jan-Erik Scholtz; Doris Leithner; Adam Spandorfer; Boris Bodelle; Volkmar Jacobi; Thomas J Vogl; Moritz H Albrecht Journal: Eur J Radiol Date: 2017-06-27 Impact factor: 3.528
Authors: Damiano Caruso; Ashley H Parinella; U Joseph Schoepf; Maxwell H Stroebel; Stefanie Mangold; Julian L Wichmann; Akos Varga-Szemes; B Devon Ball; Domenico De Santis; Andrea Laghi; Carlo N De Cecco Journal: Abdom Radiol (NY) Date: 2017-03
Authors: Moritz H Albrecht; Jesko Trommer; Julian L Wichmann; Jan-Erik Scholtz; Simon S Martin; Thomas Lehnert; Thomas J Vogl; Boris Bodelle Journal: Invest Radiol Date: 2016-09 Impact factor: 6.016
Authors: Carlo N De Cecco; Damiano Caruso; U Joseph Schoepf; Julian L Wichmann; Janet R Ter Louw; Jonathan D Perry; Melissa M Picard; Amanda R Schaefer; Leland W Parker; Andrew D Hardie Journal: Eur J Radiol Date: 2016-01-21 Impact factor: 3.528
Authors: M Kayan; H Demirtas; Y Türker; F Kayan; G Çetinkaya; M Kara; A Orhan Çelik; A Umul; Ö Yılmaz; A Recep Aktaş Journal: Diagn Interv Imaging Date: 2016-07-12 Impact factor: 4.026
Authors: David Zopfs; Simon Lennartz; Nuran Abdullayev; Thorsten Lichtenstein; Kai Roman Laukamp; Robert Peter Reimer; Christoph Kabbasch; Jan Borggrefe; Marc Schlamann; Victor Neuhaus; Nils Große Hokamp Journal: Quant Imaging Med Surg Date: 2021-08
Authors: Lucian Beer; Michael Toepker; Ahmed Ba-Ssalamah; Christian Schestak; Anja Dutschke; Martin Schindl; Alexander Wressnegger; Helmut Ringl; Paul Apfaltrer Journal: Eur Radiol Date: 2019-03-19 Impact factor: 5.315