Long Zhou 1 , Liancheng Zhao 1 , Yong Wu 2 , Yangfeng Wu 3 , Xiangmin Gao 2 , Ying Li 1 , Jinzhuang Mai 2 , Zhiqiang Nie 2 , Yanqiu Ou 2 , Min Guo 1 , Xiaoqing Liu 2 Show Affiliations »
Abstract
BACKGROUND: The American Heart Association (AHA) developed a simplified assessment tool based on seven ideal cardiovascular health (CVH) metrics, but the relationship between the AHA defined ideal CVH metrics and cardiovascular risk in Chinese population has not been well estimated. METHODS: The baseline survey were conducted among 938 Chinese men and women from four urban and rural population samples in China, aged 35-59 years in 1983-1984. The cohort was followed up for multiple cardiovascular endpoints up to 2005. Cox proportional hazard models were used to test the associations accounting for multiple covariates. Outcomes were collected in 1987-2005 and data analysed in 2017. RESULTS: During a median of 20.3 years follow-up, 68 non-fatal CVD events and 139 deaths (29 CVD deaths) occurred. The multivariable adjusted HRs and 95% CIs for all CVD in the groups with three and 4-7 ideal CVH metrics were 0.59 (95% CI 0.33 to 1.04) and 0.24 (95% CI 0.12 to 0.47), when the group with 0-2 ideal CVH metrics as the reference. Results also showed that participants with 4-7 ideal CVH metrics had a 54% (95% CI 24% to 72%) lower risk of all-cause mortality in comparison with those with 0-2 ideal metrics. CONCLUSIONS: The number of ideal CVH metrics was inversely associated with the risk of cardiovascular morbidity and mortality in this Chinese general population. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
BACKGROUND: The American Heart Association (AHA) developed a simplified assessment tool based on seven ideal cardiovascular health (CVH) metrics, but the relationship between the AHA defined ideal CVH metrics and cardiovascular risk in Chinese population has not been well estimated. METHODS: The baseline survey were conducted among 938 Chinese men and women from four urban and rural population samples in China, aged 35-59 years in 1983-1984. The cohort was followed up for multiple cardiovascular endpoints up to 2005. Cox proportional hazard models were used to test the associations accounting for multiple covariates. Outcomes were collected in 1987-2005 and data analysed in 2017. RESULTS: During a median of 20.3 years follow-up, 68 non-fatal CVD events and 139 deaths (29 CVD deaths ) occurred. The multivariable adjusted HRs and 95% CIs for all CVD in the groups with three and 4-7 ideal CVH metrics were 0.59 (95% CI 0.33 to 1.04) and 0.24 (95% CI 0.12 to 0.47), when the group with 0-2 ideal CVH metrics as the reference. Results also showed that participants with 4-7 ideal CVH metrics had a 54% (95% CI 24% to 72%) lower risk of all-cause mortality in comparison with those with 0-2 ideal metrics. CONCLUSIONS: The number of ideal CVH metrics was inversely associated with the risk of cardiovascular morbidity and mortality in this Chinese general population. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2018. All rights reserved. No commercial use is permitted unless otherwise expressly granted.
Entities: Disease
Species
Keywords:
cardiovascular disease; cohort studies; epidemiology of cardiovascular disease
Mesh： See more »
Year: 2018
PMID： 29653994 DOI： 10.1136/jech-2017-210396
Source DB: PubMed Journal: J Epidemiol Community Health ISSN： 0143-005X Impact factor: 3.710