Literature DB >> 6086008

Transcriptional regulation of hemoglobin switching in chicken embryos.

M Groudine1, M Peretz, H Weintraub.   

Abstract

We used recombinant chicken deoxyribonucleic acid clones containing embryonic and adult beta-globin genes and "runoff" endogenous nuclear transcription to investigate the expression of embryonic and adult beta-globin genes during hematopoiesis in the developing chicken embryo. Purified, cloned deoxyribonucleic acids were digested with various restriction enzymes, separated on agarose gels, blotted to nitrocellulose, and annealed with purified nuclear [32P]ribonucleic acid synthesized in vitro from embryonic or adult red cell nuclei. Transcription of the respective globin genes was assayed by hybridization of nuclear [32P]ribonucleic acid to specific restriction fragments containing adult or embryonic coding sequences. Our results indicate that little, if any, transcription from the adult or embryonic beta-globin genes is detectable in the heterologous red cell nuclei, even under conditions in which ribonucleic acid processing probably does not occur.

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Year:  1981        PMID： 6086008      PMCID： PMC369672          DOI： 10.1128/mcb.1.3.281-288.1981

Source DB:  PubMed          Journal:  Mol Cell Biol        ISSN： 0270-7306            Impact factor:   4.272


  18 in total

1.  Efficient transfer of large DNA fragments from agarose gels to diazobenzyloxymethyl-paper and rapid hybridization by using dextran sulfate.

Authors:  G M Wahl; M Stern; G R Stark
Journal:  Proc Natl Acad Sci U S A       Date:  1979-08       Impact factor: 11.205

2.  Isolation and characterization of recombinant clones containing the chicken adult beta-globin gene.

Authors:  G D Ginder; W I Wood; G Felsenfeld
Journal:  J Biol Chem       Date:  1979-09-10       Impact factor: 5.157

3.  Distribution of developmentally regulated hemoglobins in embryonic erythroid populations.

Authors:  B S Chapman; A J Tobin
Journal:  Dev Biol       Date:  1979-04       Impact factor: 3.582

4.  Organization of polysomes from pre-existing ribosomes in chick oviduct by a secondary administration of either estradiol or progesterone.

Authors:  R D Palmiter; A K Christensen; R T Schimke
Journal:  J Biol Chem       Date:  1970-02-25       Impact factor: 5.157

5.  Hb switching in chickens.

Authors:  J Stalder; M Groudine; J B Dodgson; J D Engel; H Weintraub
Journal:  Cell       Date:  1980-04       Impact factor: 41.582

6.  Tissue-specific DNA cleavages in the globin chromatin domain introduced by DNAase I.

Authors:  J Stalder; A Larsen; J D Engel; M Dolan; M Groudine; H Weintraub
Journal:  Cell       Date:  1980-06       Impact factor: 41.582

7.  Transcriptional regulation of the ovalbumin and conalbumin genes by steroid hormones in chick oviduct.

Authors:  G S McKnight; R D Palmiter
Journal:  J Biol Chem       Date:  1979-09-25       Impact factor: 5.157

8.  Selective and accurate initiation of transcription at the Ad2 major late promotor in a soluble system dependent on purified RNA polymerase II and DNA.

Authors:  P A Weil; D S Luse; J Segall; R G Roeder
Journal:  Cell       Date:  1979-10       Impact factor: 41.582

9.  Isolation of the chicken beta-globin gene and a linked embryonic beta-like globin gene from a chicken DNA recombinant library.

Authors:  J B Dodgson; J Strommer; J D Engel
Journal:  Cell       Date:  1979-08       Impact factor: 41.582

10.  Transcription of adenoviral genetic information in isolated nuclei. Characterization of viral RNA sequences synthesized in vitro.

Authors:  V W Yang; M H Binger; S J Flint
Journal:  J Biol Chem       Date:  1980-03-10       Impact factor: 5.157
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  254 in total

1.  Host-cell positive transcription elongation factor b kinase activity is essential and limiting for HIV type 1 replication.

Authors:  O Flores; G Lee; J Kessler; M Miller; W Schlief; J Tomassini; D Hazuda
Journal:  Proc Natl Acad Sci U S A       Date:  1999-06-22       Impact factor: 11.205

2.  Genomic targeting of methylated DNA: influence of methylation on transcription, replication, chromatin structure, and histone acetylation.

Authors:  D Schübeler; M C Lorincz; D M Cimbora; A Telling; Y Q Feng; E E Bouhassira; M Groudine
Journal:  Mol Cell Biol       Date:  2000-12       Impact factor: 4.272

3.  Transcriptional analyses of antifungal drug resistance in Candida albicans.

Authors:  C N Lyons; T C White
Journal:  Antimicrob Agents Chemother       Date:  2000-09       Impact factor: 5.191

4.  Fusion genes resulting from alternative chromosomal translocations are overexpressed by gene-specific mechanisms in alveolar rhabdomyosarcoma.

Authors:  R J Davis; F G Barr
Journal:  Proc Natl Acad Sci U S A       Date:  1997-07-22       Impact factor: 11.205

5.  The primary transcription unit of the human alpha 2 globin gene defined by quantitative RT/PCR.

Authors:  C M Owczarek; P Enriquez-Harris; N J Proudfoot
Journal:  Nucleic Acids Res       Date:  1992-02-25       Impact factor: 16.971

6.  Selective translational control and nonspecific posttranscriptional regulation of ribosomal protein gene expression during development and regeneration of rat liver.

Authors:  R Aloni; D Peleg; O Meyuhas
Journal:  Mol Cell Biol       Date:  1992-05       Impact factor: 4.272

7.  The role of the promoter in the expression of the PCNA gene.

Authors:  R H Charollais; H Alder; A Ferber; J Koniecki; C Sell; R Baserga
Journal:  Gene Expr       Date:  1992

8.  Regulated expression of the human acetylated low density lipoprotein receptor gene and isolation of promoter sequences.

Authors:  K S Moulton; H Wu; J Barnett; S Parthasarathy; C K Glass
Journal:  Proc Natl Acad Sci U S A       Date:  1992-09-01       Impact factor: 11.205

9.  Beta interferon subtype 1 induction by tumor necrosis factor.

Authors:  H Jacobsen; J Mestan; S Mittnacht; C W Dieffenbach
Journal:  Mol Cell Biol       Date:  1989-07       Impact factor: 4.272

10.  Regulation of 4F2 heavy-chain gene expression during normal human T-cell activation can be mediated by multiple distinct molecular mechanisms.

Authors:  T Lindsten; C H June; C B Thompson; J M Leiden
Journal:  Mol Cell Biol       Date:  1988-09       Impact factor: 4.272
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