Sattamat Lappharat1, Nutta Taneepanichskul1, Sirimon Reutrakul2,3, Naricha Chirakalwasan4,5. 1. College of Public Health Sciences, Chulalongkorn University, Bangkok, Thailand. 2. Division of Endocrinology and Metabolism, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Ratchathewi, Bangkok, Thailand. 3. Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Illinois at Chicago, Chicago, Illinois. 4. Excellence Center for Sleep Disorders, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand. 5. Division of Pulmonary and Critical Care Medicine, Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Abstract
STUDY OBJECTIVES: Epidemiological associations have demonstrated the effects of long-term air pollution to obstructive sleep apnea (OSA) through a physiological mechanism linking particulate matter exposure to OSA. This study aimed to determine the relationship between bedroom environmental conditions, OSA severity, and sleep quality. METHODS: Sixty-three participants were enrolled for an overnight polysomnography; OSA was diagnosed between May to August 2016. Personal characteristics and sleep quality were obtained by a face-to-face interview. Bedroom environments, including data on particulate matter with an aerodynamic diameter less than 10 μm (PM10), temperature, and relative humidity, were collected by personal air sampling and a HOBO tempt/RH data logger. RESULTS: Sixty-eight percent of the participants experienced poor sleep. An elevation in 1-year mean PM10 concentration was significantly associated with an increase in apnea-hypopnea index (beta = 1.04, P = .021) and respiratory disturbance index (beta = 1.07, P = .013). An increase of bedroom temperature during sleep was significantly associated with poorer sleep quality (adjusted odds ratio 1.46, 95% confidence interval 1.01-2.10, P = .044). Associations between PM10 concentration and respiratory disturbance index were observed in the dry season (beta = 0.59, P = .040) but not in the wet season (beta = 0.39, P = .215). PM10 was not associated with subjective sleep quality. CONCLUSIONS: Elevation of PM10 concentration is significantly associated with increased OSA severity. Our findings suggest that reduction in exposure to particulate matter and suitable bedroom environments may lessen the severity of OSA and promote good sleep.
STUDY OBJECTIVES: Epidemiological associations have demonstrated the effects of long-term air pollution to obstructive sleep apnea (OSA) through a physiological mechanism linking particulate matter exposure to OSA. This study aimed to determine the relationship between bedroom environmental conditions, OSA severity, and sleep quality. METHODS: Sixty-three participants were enrolled for an overnight polysomnography; OSA was diagnosed between May to August 2016. Personal characteristics and sleep quality were obtained by a face-to-face interview. Bedroom environments, including data on particulate matter with an aerodynamic diameter less than 10 μm (PM10), temperature, and relative humidity, were collected by personal air sampling and a HOBO tempt/RH data logger. RESULTS: Sixty-eight percent of the participants experienced poor sleep. An elevation in 1-year mean PM10 concentration was significantly associated with an increase in apnea-hypopnea index (beta = 1.04, P = .021) and respiratory disturbance index (beta = 1.07, P = .013). An increase of bedroom temperature during sleep was significantly associated with poorer sleep quality (adjusted odds ratio 1.46, 95% confidence interval 1.01-2.10, P = .044). Associations between PM10 concentration and respiratory disturbance index were observed in the dry season (beta = 0.59, P = .040) but not in the wet season (beta = 0.39, P = .215). PM10 was not associated with subjective sleep quality. CONCLUSIONS: Elevation of PM10 concentration is significantly associated with increased OSA severity. Our findings suggest that reduction in exposure to particulate matter and suitable bedroom environments may lessen the severity of OSA and promote good sleep.
Authors: Antonella Zanobetti; Susan Redline; Joel Schwartz; Dennis Rosen; Sanjay Patel; George T O'Connor; Michael Lebowitz; Brent A Coull; Diane R Gold Journal: Am J Respir Crit Care Med Date: 2010-05-27 Impact factor: 21.405
Authors: Susan Redline; Gayane Yenokyan; Daniel J Gottlieb; Eyal Shahar; George T O'Connor; Helaine E Resnick; Marie Diener-West; Mark H Sanders; Philip A Wolf; Estella M Geraghty; Tauqeer Ali; Michael Lebowitz; Naresh M Punjabi Journal: Am J Respir Crit Care Med Date: 2010-03-25 Impact factor: 21.405
Authors: Patricia F Coogan; Laura F White; Michael Jerrett; Robert D Brook; Jason G Su; Edmund Seto; Richard Burnett; Julie R Palmer; Lynn Rosenberg Journal: Circulation Date: 2012-01-04 Impact factor: 29.690
Authors: A Campbell; M Oldham; A Becaria; S C Bondy; D Meacher; C Sioutas; C Misra; L B Mendez; M Kleinman Journal: Neurotoxicology Date: 2005-01 Impact factor: 4.294
Authors: Bing Wang; Wei Y Feng; Meng Wang; Jun W Shi; Fang Zhang; Hong Ouyang; Yu L Zhao; Zhi F Chai; Yu Y Huang; Ya N Xie; Hai F Wang; Jing Wang Journal: Biol Trace Elem Res Date: 2007-09 Impact factor: 3.738
Authors: Michelle S Glaser; Neomi Shah; Mayris P Webber; Rachel Zeig-Owens; Nadia Jaber; David W Appel; Charles B Hall; Jessica Weakley; Hillel W Cohen; Lawrence Shulman; Kerry Kelly; David Prezant Journal: J Occup Environ Med Date: 2014-10 Impact factor: 2.162