Kayci L Vickers1,2, Kathleen Breslin1,3, David R Roalf4, Vidyulata Kamath5, Sharon X Xie6, Paul J Moberg1,4, David A Wolk1, Dawn Mechanic-Hamilton1. 1. Alzheimer's Disease Center, Department of Neurology, Perelman School of Medicine, Philadelphia, PA, USA. 2. Department of Psychology, Drexel University, Philadelphia, PA, USA. 3. Department of Psychology, Pennsylvania College of Osteopathic Medicine, Philadelphia, PA, USA. 4. Brain Behavior Laboratory, Department of Psychiatry, Perelman School of Medicine, Philadelphia, PA, USA. 5. Department of Psychiatry and Behavioral Sciences, Johns Hopkins University, Baltimore, MA, USA. 6. Department of Biostatistics and Epidemiology, Perelman School of Medicine, Philadelphia, PA, USA.
Abstract
OBJECTIVE: The current study establishes normative Sniffin' Sticks Odor Identification Test (SS-OIT) scores for cognitively intact older adults. METHOD: Two hundred and twenty-six cognitively normal older adults were identified as eligible for the current study (Mean Age = 70.49 years; 71.7% female). Important demographic covariates were identified using step-wise regression, and a normative regression equation was developed. RESULTS: Analyses of the effects of demographic variables (including age, education, and sex) on SS-OIT performance revealed that age was the only significant predictor, b = -0.07, SEb = .01, p < .01. A final regression equation was determined and normative data are reported in 5-year increments for a number of percentile ranks. CONCLUSIONS: Normative performance on the SS-OIT for adults over the age of 50 was established in a large and demographically diverse sample. These data are needed in order for clinicians to be able to include olfactory testing, a sensitive marker of neurodegeneration, in their assessment armamentarium.
OBJECTIVE: The current study establishes normative Sniffin' Sticks Odor Identification Test (SS-OIT) scores for cognitively intact older adults. METHOD: Two hundred and twenty-six cognitively normal older adults were identified as eligible for the current study (Mean Age = 70.49 years; 71.7% female). Important demographic covariates were identified using step-wise regression, and a normative regression equation was developed. RESULTS: Analyses of the effects of demographic variables (including age, education, and sex) on SS-OIT performance revealed that age was the only significant predictor, b = -0.07, SEb = .01, p < .01. A final regression equation was determined and normative data are reported in 5-year increments for a number of percentile ranks. CONCLUSIONS: Normative performance on the SS-OIT for adults over the age of 50 was established in a large and demographically diverse sample. These data are needed in order for clinicians to be able to include olfactory testing, a sensitive marker of neurodegeneration, in their assessment armamentarium.
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