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Literature DB >> 29606309

Targeting Biophysical Cues: a Niche Approach to Study, Diagnose, and Treat Cancer.

Shirley X Zhang¹, Linan Liu², Weian Zhao³.

Abstract

Probing the biophysical properties of the tumor niche offers a new perspective in cancer mechanobiology, and supports the development of next-generation diagnostics and therapeutics for cancer, in particular for metastasis.

Entities: CellLine Chemical Disease Gene Species

Keywords: biophysical cues; cancer; mechanobiology; metastasis; microenvironment; stem cell

Mesh：

Substances：

Year: 2018 PMID： 29606309 PMCID： PMC6226275 DOI： 10.1016/j.trecan.2018.02.006

Source DB: PubMed Journal: Trends Cancer ISSN： 2405-8025

14 in total

1. Matrix elasticity directs stem cell lineage specification.

Authors: Adam J Engler; Shamik Sen; H Lee Sweeney; Dennis E Discher
Journal: Cell Date: 2006-08-25 Impact factor: 41.582

2. Role of YAP/TAZ in mechanotransduction.

Authors: Sirio Dupont; Leonardo Morsut; Mariaceleste Aragona; Elena Enzo; Stefano Giulitti; Michelangelo Cordenonsi; Francesca Zanconato; Jimmy Le Digabel; Mattia Forcato; Silvio Bicciato; Nicola Elvassore; Stefano Piccolo
Journal: Nature Date: 2011-06-08 Impact factor: 49.962

Review 3. Biomaterials and emerging anticancer therapeutics: engineering the microenvironment.

Authors: Luo Gu; David J Mooney
Journal: Nat Rev Cancer Date: 2016-01 Impact factor: 60.716

4. Fibrosis and Cancer: Partners in Crime or Opposing Forces?

Authors: Thomas R Cox; Janine T Erler
Journal: Trends Cancer Date: 2016-05-30

5. Fine Needle Elastography (FNE) device for biomechanically determining local variations of tissue mechanical properties.

Authors: Dayan Wickramaratne; Paul Wilkinson; JianYu Rao; Nagesh Ragavendra; Shivani Sharma; James K Gimzewski
Journal: J Biomech Date: 2014-11-14 Impact factor: 2.712

6. Matrix crosslinking forces tumor progression by enhancing integrin signaling.

Authors: Kandice R Levental; Hongmei Yu; Laura Kass; Johnathon N Lakins; Mikala Egeblad; Janine T Erler; Sheri F T Fong; Katalin Csiszar; Amato Giaccia; Wolfgang Weninger; Mitsuo Yamauchi; David L Gasser; Valerie M Weaver
Journal: Cell Date: 2009-11-25 Impact factor: 41.582

Targeting Biophysical Cues: a Niche Approach to Study, Diagnose, and Treat Cancer.

1. Matrix elasticity directs stem cell lineage specification.

2. Role of YAP/TAZ in mechanotransduction.

Review 3. Biomaterials and emerging anticancer therapeutics: engineering the microenvironment.

4. Fibrosis and Cancer: Partners in Crime or Opposing Forces?

5. Fine Needle Elastography (FNE) device for biomechanically determining local variations of tissue mechanical properties.

6. Matrix crosslinking forces tumor progression by enhancing integrin signaling.

Review 7. Targeting the tumor microenvironment for cancer therapy.

8. Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer.

Review 9. The extracellular matrix: a dynamic niche in cancer progression.

10. Imaging of lymph node micrometastases using an oncolytic herpes virus and [F]FEAU PET.

Review 1. Mechano-therapeutics: Targeting Mechanical Signaling in Fibrosis and Tumor Stroma.

Review 2. Electrical stimulation as a novel tool for regulating cell behavior in tissue engineering.