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Literature DB >> 28741525

Fibrosis and Cancer: Partners in Crime or Opposing Forces?

Abstract

The relation between fibrosis and cancer has long been debated, specifically whether desmoplasia precedes, accompanies, or succeeds tumourigenesis, progression, and metastasis. Recent reports have published opposing data, adding to the perplexity. However, what is emerging is that it is likely the specific properties of the extracellular matrix (ECM) that determine the paradoxical nature of cancer-associated fibrosis.

Entities: Disease

Mesh：

Year: 2016 PMID： 28741525 DOI： 10.1016/j.trecan.2016.05.004

Source DB: PubMed Journal: Trends Cancer ISSN： 2405-8025

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Cited

20 in total

Review 1. Integration of inflammation, fibrosis, and cancer induced by carbon nanotubes.

Authors: Jie Dong; Qiang Ma
Journal: Nanotoxicology Date: 2019-09-19 Impact factor: 5.913

Review 2. The interplay between extracellular matrix remodelling and kinase signalling in cancer progression and metastasis.

Authors: Joanna N Skhinas; Thomas R Cox
Journal: Cell Adh Migr Date: 2017-12-29 Impact factor: 3.405

Review 3. The extracellular matrix as a key regulator of intracellular signalling networks.

Authors: Jordan F Hastings; Joanna N Skhinas; Dirk Fey; David R Croucher; Thomas R Cox
Journal: Br J Pharmacol Date: 2018-04-19 Impact factor: 8.739

Review 4. The matrix in cancer.

Authors: Thomas R Cox
Journal: Nat Rev Cancer Date: 2021-02-15 Impact factor: 60.716

5. Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.

Authors: Claire Vennin; Venessa T Chin; Sean C Warren; Morghan C Lucas; David Herrmann; Astrid Magenau; Pauline Melenec; Stacey N Walters; Gonzalo Del Monte-Nieto; James R W Conway; Max Nobis; Amr H Allam; Rachael A McCloy; Nicola Currey; Mark Pinese; Alice Boulghourjian; Anaiis Zaratzian; Arne A S Adam; Celine Heu; Adnan M Nagrial; Angela Chou; Angela Steinmann; Alison Drury; Danielle Froio; Marc Giry-Laterriere; Nathanial L E Harris; Tri Phan; Rohit Jain; Wolfgang Weninger; Ewan J McGhee; Renee Whan; Amber L Johns; Jaswinder S Samra; Lorraine Chantrill; Anthony J Gill; Maija Kohonen-Corish; Richard P Harvey; Andrew V Biankin; T R Jeffry Evans; Kurt I Anderson; Shane T Grey; Christopher J Ormandy; David Gallego-Ortega; Yingxiao Wang; Michael S Samuel; Owen J Sansom; Andrew Burgess; Thomas R Cox; Jennifer P Morton; Marina Pajic; Paul Timpson
Journal: Sci Transl Med Date: 2017-04-05 Impact factor: 17.956

Fibrosis and Cancer: Partners in Crime or Opposing Forces?

Review 1. Integration of inflammation, fibrosis, and cancer induced by carbon nanotubes.

Review 2. The interplay between extracellular matrix remodelling and kinase signalling in cancer progression and metastasis.

Review 3. The extracellular matrix as a key regulator of intracellular signalling networks.

Review 4. The matrix in cancer.

5. Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.

6. Air pollution particles hijack peroxidasin to disrupt immunosurveillance and promote lung cancer.

7. Relative Stiffness Measurements of Tumour Tissues by Shear Rheology.

Review 8. Clinical and therapeutic relevance of cancer-associated fibroblasts.

Review 9. Targeting Biophysical Cues: a Niche Approach to Study, Diagnose, and Treat Cancer.

Review 10. Targeting ROCK activity to disrupt and prime pancreatic cancer for chemotherapy.