Literature DB >> 29603285

DNA Repair: The Search for Homology.

James E Haber1.   

Abstract

The repair of chromosomal double-strand breaks (DSBs) by homologous recombination is essential to maintain genome integrity. The key step in DSB repair is the RecA/Rad51-mediated process to match sequences at the broken end to homologous donor sequences that can be used as a template to repair the lesion. Here, in reviewing research about DSB repair, I consider the many factors that appear to play important roles in the successful search for homology by several homologous recombination mechanisms. See also the video abstract here: https://youtu.be/vm7-X5uIzS8.
© 2018 WILEY Periodicals, Inc.

Entities:  

Keywords:  DNA strand invasion; Rad51/RecA; double-strand break repair; homologous recombination; search for homology

Mesh：

Substances：

Year:  2018        PMID： 29603285      PMCID： PMC6238635          DOI： 10.1002/bies.201700229

Source DB:  PubMed          Journal:  Bioessays        ISSN： 0265-9247            Impact factor:   4.345


  105 in total

1.  Sister chromatid cohesion is required for postreplicative double-strand break repair in Saccharomyces cerevisiae.

Authors:  C Sjögren; K Nasmyth
Journal:  Curr Biol       Date:  2001-06-26       Impact factor: 10.834

2.  Evidence for a dual role of actin in regulating chromosome organization and dynamics in yeast.

Authors:  Maya Spichal; Alice Brion; Sébastien Herbert; Axel Cournac; Martial Marbouty; Christophe Zimmer; Romain Koszul; Emmanuelle Fabre
Journal:  J Cell Sci       Date:  2016-01-13       Impact factor: 5.285

3.  Break-induced replication occurs by conservative DNA synthesis.

Authors:  Roberto A Donnianni; Lorraine S Symington
Journal:  Proc Natl Acad Sci U S A       Date:  2013-07-29       Impact factor: 11.205

4.  Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures.

Authors:  Zhucheng Chen; Haijuan Yang; Nikola P Pavletich
Journal:  Nature       Date:  2008-05-22       Impact factor: 49.962

Review 5.  Break-induced replication: what is it and what is it for?

Authors:  Bertrand Llorente; Catherine E Smith; Lorraine S Symington
Journal:  Cell Cycle       Date:  2008-01-14       Impact factor: 4.534

6.  Frequent Interchromosomal Template Switches during Gene Conversion in S. cerevisiae.

Authors:  Olga Tsaponina; James E Haber
Journal:  Mol Cell       Date:  2014-07-24       Impact factor: 17.970

7.  Histone degradation in response to DNA damage enhances chromatin dynamics and recombination rates.

Authors:  Michael H Hauer; Andrew Seeber; Vijender Singh; Raphael Thierry; Ragna Sack; Assaf Amitai; Mariya Kryzhanovska; Jan Eglinger; David Holcman; Tom Owen-Hughes; Susan M Gasser
Journal:  Nat Struct Mol Biol       Date:  2017-01-09       Impact factor: 15.369

8.  Monitoring homology search during DNA double-strand break repair in vivo.

Authors:  Jörg Renkawitz; Claudio A Lademann; Marian Kalocsay; Stefan Jentsch
Journal:  Mol Cell       Date:  2013-03-21       Impact factor: 17.970

Review 9.  Mutations arising during repair of chromosome breaks.

Authors:  Anna Malkova; James E Haber
Journal:  Annu Rev Genet       Date:  2012       Impact factor: 16.830

10.  The Fun30 nucleosome remodeller promotes resection of DNA double-strand break ends.

Authors:  Xuefeng Chen; Dandan Cui; Alma Papusha; Xiaotian Zhang; Chia-Dwo Chu; Jiangwu Tang; Kaifu Chen; Xuewen Pan; Grzegorz Ira
Journal:  Nature       Date:  2012-09-09       Impact factor: 49.962
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  31 in total

1.  Cancer-driving H3G34V/R/D mutations block H3K36 methylation and H3K36me3-MutSα interaction.

Authors:  Jun Fang; Yaping Huang; Guogen Mao; Shuang Yang; Gadi Rennert; Liya Gu; Haitao Li; Guo-Min Li
Journal:  Proc Natl Acad Sci U S A       Date:  2018-09-04       Impact factor: 11.205

Review 2.  RAD51 Gene Family Structure and Function.

Authors:  Braulio Bonilla; Sarah R Hengel; McKenzie K Grundy; Kara A Bernstein
Journal:  Annu Rev Genet       Date:  2020-07-14       Impact factor: 16.830

3.  Rad54 Drives ATP Hydrolysis-Dependent DNA Sequence Alignment during Homologous Recombination.

Authors:  J Brooks Crickard; Corentin J Moevus; Youngho Kwon; Patrick Sung; Eric C Greene
Journal:  Cell       Date:  2020-06-04       Impact factor: 41.582

Review 4.  Telomere and Subtelomere R-loops and Antigenic Variation in Trypanosomes.

Authors:  Arpita Saha; Vishal P Nanavaty; Bibo Li
Journal:  J Mol Biol       Date:  2019-11-02       Impact factor: 5.469

5.  Modified chromosome structure caused by phosphomimetic H2A modulates the DNA damage response by increasing chromatin mobility in yeast.

Authors:  Fabiola García Fernández; Brenda Lemos; Yasmine Khalil; Renaud Batrin; James E Haber; Emmanuelle Fabre
Journal:  J Cell Sci       Date:  2021-03-29       Impact factor: 5.285

6.  Two class II CPD photolyases, PiPhr1 and PiPhr2, with CPD repair activity from the Antarctic diatom Phaeodactylum tricornutum ICE-H.

Authors:  Meiling An; Changfeng Qu; Jinlai Miao; Zhenxia Sha
Journal:  3 Biotech       Date:  2021-07-21       Impact factor: 2.893

7.  Unchecked nick ligation can promote localized genome re-replication.

Authors:  Erik Johansson; John F X Diffley
Journal:  Curr Biol       Date:  2021-06-07       Impact factor: 10.834

Review 8.  Keeping Balance Between Genetic Stability and Plasticity at the Telomere and Subtelomere of Trypanosoma brucei.

Authors:  Bibo Li
Journal:  Front Cell Dev Biol       Date:  2021-07-05

9.  Rad52 Oligomeric N-Terminal Domain Stabilizes Rad51 Nucleoprotein Filaments and Contributes to Their Protection against Srs2.

Authors:  Emilie Ma; Laurent Maloisel; Léa Le Falher; Raphaël Guérois; Eric Coïc
Journal:  Cells       Date:  2021-06-11       Impact factor: 6.600

Review 10.  Hexavalent chromium disrupts chromatin architecture.

Authors:  Andrew VonHandorf; Hesbon A Zablon; Alvaro Puga
Journal:  Semin Cancer Biol       Date:  2021-07-15       Impact factor: 15.707
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