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Literature DB >> 29603068

The significance and application of vascular niche in the development and maintenance of hematopoietic stem cells.

Abstract

Deriving hematopoietic stem cells (HSCs) from human pluripotent stem cells is one of major goals in stem cell and hematological research. To induce HSCs from human pluripotent stem cells, many attempts to mimic embryonic development through stepwise exposure to morphogens. HSCs arise from dorsal aorta of embryos then migrate and settle in the bone marrow. Development and maintenance of HSCs are controlled by the microenvironmental cues around the blood vessels (called vascular niche) through morphogens and cytokines. Vascular niche serves as a common mechanism from embryo development to life-long maintenance of HSCs. In this chapter, I discuss that how vascular niche regulates development and maintenance of HSCs and exemplify the role of vascular niche to exquisitely induce HSCs from human pluripotent stem cells.

Entities: Species

Keywords: Hematopoietic stem cell; Niche; Pluripotent stem cell; Signaling; Transcriptional regulation

Mesh：

Substances：
Cytokines

Year: 2018 PMID： 29603068 DOI： 10.1007/s12185-018-2450-2

Source DB: PubMed Journal: Int J Hematol ISSN： 0925-5710 Impact factor: 2.490

13 in total

1. SLAM family receptors distinguish hematopoietic stem and progenitor cells and reveal endothelial niches for stem cells.

Authors: Mark J Kiel; Omer H Yilmaz; Toshihide Iwashita; Osman H Yilmaz; Cox Terhorst; Sean J Morrison
Journal: Cell Date: 2005-07-01 Impact factor: 41.582

2. Definitive hematopoiesis is autonomously initiated by the AGM region.

Authors: A Medvinsky; E Dzierzak
Journal: Cell Date: 1996-09-20 Impact factor: 41.582

3. Differentiation of human embryonic stem cells to HOXA⁺ hemogenic vasculature that resembles the aorta-gonad-mesonephros.

Authors: Elizabeth S Ng; Lisa Azzola; Freya F Bruveris; Vincenzo Calvanese; Belinda Phipson; Katerina Vlahos; Claire Hirst; Vanta J Jokubaitis; Qing C Yu; Jovana Maksimovic; Simone Liebscher; Vania Januar; Zhen Zhang; Brenda Williams; Aude Conscience; Jennifer Durnall; Steven Jackson; Magdaline Costa; David Elliott; David N Haylock; Susan K Nilsson; Richard Saffery; Katja Schenke-Layland; Alicia Oshlack; Hanna K A Mikkola; Edouard G Stanley; Andrew G Elefanty
Journal: Nat Biotechnol Date: 2016-10-17 Impact factor: 54.908

4. Cord blood expansion. Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal.

Authors: Iman Fares; Jalila Chagraoui; Yves Gareau; Stéphane Gingras; Réjean Ruel; Nadine Mayotte; Elizabeth Csaszar; David J H F Knapp; Paul Miller; Mor Ngom; Suzan Imren; Denis-Claude Roy; Kori L Watts; Hans-Peter Kiem; Robert Herrington; Norman N Iscove; R Keith Humphries; Connie J Eaves; Sandra Cohen; Anne Marinier; Peter W Zandstra; Guy Sauvageau
Journal: Science Date: 2014-09-19 Impact factor: 47.728

5. Hematopoietic Stem Cell Niches Produce Lineage-Instructive Signals to Control Multipotent Progenitor Differentiation.

Authors: Ana Cordeiro Gomes; Takahiro Hara; Vivian Y Lim; Dietmar Herndler-Brandstetter; Erin Nevius; Tatsuki Sugiyama; Shizue Tani-Ichi; Susan Schlenner; Ellen Richie; Hans-Reimer Rodewald; Richard A Flavell; Takashi Nagasawa; Koichi Ikuta; João Pedro Pereira
Journal: Immunity Date: 2016-11-29 Impact factor: 43.474

6. Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region.

Authors: Andrejs Ivanovs; Stanislav Rybtsov; Lindsey Welch; Richard A Anderson; Marc L Turner; Alexander Medvinsky
Journal: J Exp Med Date: 2011-10-31 Impact factor: 14.307

Review 7. The bone marrow niche for haematopoietic stem cells.

Authors: Sean J Morrison; David T Scadden
Journal: Nature Date: 2014-01-16 Impact factor: 49.962

8. Arteriolar niches maintain haematopoietic stem cell quiescence.

Authors: Yuya Kunisaki; Ingmar Bruns; Christoph Scheiermann; Jalal Ahmed; Sandra Pinho; Dachuan Zhang; Toshihide Mizoguchi; Qiaozhi Wei; Daniel Lucas; Keisuke Ito; Jessica C Mar; Aviv Bergman; Paul S Frenette
Journal: Nature Date: 2013-10-09 Impact factor: 49.962

9. A humanized bone marrow ossicle xenotransplantation model enables improved engraftment of healthy and leukemic human hematopoietic cells.

Authors: Andreas Reinisch; Daniel Thomas; M Ryan Corces; Xiaohua Zhang; Dita Gratzinger; Wan-Jen Hong; Katharina Schallmoser; Dirk Strunk; Ravindra Majeti
Journal: Nat Med Date: 2016-05-23 Impact factor: 53.440

10. Haematopoietic stem and progenitor cells from human pluripotent stem cells.

Authors: Ryohichi Sugimura; Deepak Kumar Jha; Areum Han; Clara Soria-Valles; Edroaldo Lummertz da Rocha; Yi-Fen Lu; Jeremy A Goettel; Erik Serrao; R Grant Rowe; Mohan Malleshaiah; Irene Wong; Patricia Sousa; Ted N Zhu; Andrea Ditadi; Gordon Keller; Alan N Engelman; Scott B Snapper; Sergei Doulatov; George Q Daley
Journal: Nature Date: 2017-05-17 Impact factor: 49.962

7 in total

1. Guest editorial: Regulatory signaling in normal and abnormal hematopoiesis.

Authors: Fumio Arai
Journal: Int J Hematol Date: 2018-05-04 Impact factor: 2.490

Review 2. The vascular niche in next generation microphysiological systems.

Authors: Makena L Ewald; Yu-Hsi Chen; Abraham P Lee; Christopher C W Hughes
Journal: Lab Chip Date: 2021-08-16 Impact factor: 7.517

3. Guiding T lymphopoiesis from pluripotent stem cells by defined transcription factors.

Authors: Rongqun Guo; Fangxiao Hu; Qitong Weng; Cui Lv; Hongling Wu; Lijuan Liu; Zongcheng Li; Yang Zeng; Zhijie Bai; Mengyun Zhang; Yuting Liu; Xiaofei Liu; Chengxiang Xia; Tongjie Wang; Peiqing Zhou; Kaitao Wang; Yong Dong; Yuxuan Luo; Xiangzhong Zhang; Yuxian Guan; Yang Geng; Juan Du; Yangqiu Li; Yu Lan; Jiekai Chen; Bing Liu; Jinyong Wang
Journal: Cell Res Date: 2019-11-15 Impact factor: 46.297

Review 7. The Role of Hypoxic Bone Marrow Microenvironment in Acute Myeloid Leukemia and Future Therapeutic Opportunities.

Authors: Samantha Bruno; Manuela Mancini; Sara De Santis; Cecilia Monaldi; Michele Cavo; Simona Soverini
Journal: Int J Mol Sci Date: 2021-06-25 Impact factor: 5.923