Literature DB >> 24429631

The bone marrow niche for haematopoietic stem cells.

Sean J Morrison1, David T Scadden2.   

Abstract

Niches are local tissue microenvironments that maintain and regulate stem cells. Haematopoiesis provides a model for understanding mammalian stem cells and their niches, but the haematopoietic stem cell (HSC) niche remains incompletely defined and beset by competing models. Recent progress has been made in elucidating the location and cellular components of the HSC niche in the bone marrow. The niche is perivascular, created partly by mesenchymal stromal cells and endothelial cells and often, but not always, located near trabecular bone. Outstanding questions concern the cellular complexity of the niche, the role of the endosteum and functional heterogeneity among perivascular microenvironments.

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Year:  2014        PMID: 24429631      PMCID: PMC4514480          DOI: 10.1038/nature12984

Source DB:  PubMed          Journal:  Nature        ISSN: 0028-0836            Impact factor:   49.962


  121 in total

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Journal:  Blood       Date:  1997-11-01       Impact factor: 22.113

3.  Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells.

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Journal:  Blood       Date:  2007-01-16       Impact factor: 22.113

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Journal:  Blood       Date:  2011-06-14       Impact factor: 22.113

5.  Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche.

Authors:  Ryohichi Sugimura; Xi C He; Aparna Venkatraman; Fumio Arai; Andrew Box; Craig Semerad; Jeffrey S Haug; Lai Peng; Xiao-Bo Zhong; Toshio Suda; Linheng Li
Journal:  Cell       Date:  2012-07-20       Impact factor: 41.582

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Journal:  Blood       Date:  1997-01-01       Impact factor: 22.113

7.  Osteoblastic regulation of B lymphopoiesis is mediated by Gs{alpha}-dependent signaling pathways.

Authors:  Joy Y Wu; Louise E Purton; Stephen J Rodda; Min Chen; Lee S Weinstein; Andrew P McMahon; David T Scadden; Henry M Kronenberg
Journal:  Proc Natl Acad Sci U S A       Date:  2008-10-28       Impact factor: 11.205

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Authors:  Heather A Himburg; Jeffrey R Harris; Takahiro Ito; Pamela Daher; J Lauren Russell; Mamle Quarmyne; Phuong L Doan; Katherine Helms; Mai Nakamura; Emma Fixsen; Gonzalo Herradon; Tannishtha Reya; Nelson J Chao; Sheila Harroch; John P Chute
Journal:  Cell Rep       Date:  2012-10-19       Impact factor: 9.423

10.  Endochondral ossification is required for haematopoietic stem-cell niche formation.

Authors:  Charles K F Chan; Ching-Cheng Chen; Cynthia A Luppen; Jae-Beom Kim; Anthony T DeBoer; Kevin Wei; Jill A Helms; Calvin J Kuo; Daniel L Kraft; Irving L Weissman
Journal:  Nature       Date:  2008-12-10       Impact factor: 49.962

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  871 in total

1.  Ischemic stroke activates hematopoietic bone marrow stem cells.

Authors:  Gabriel Courties; Fanny Herisson; Hendrik B Sager; Timo Heidt; Yuxiang Ye; Ying Wei; Yuan Sun; Nicolas Severe; Partha Dutta; Jennifer Scharff; David T Scadden; Ralph Weissleder; Filip K Swirski; Michael A Moskowitz; Matthias Nahrendorf
Journal:  Circ Res       Date:  2014-10-31       Impact factor: 17.367

2.  Luteinizing hormone signaling restricts hematopoietic stem cell expansion during puberty.

Authors:  Yi Jacky Peng; Hua Yu; Xiaoxin Hao; Wenjie Dong; Xiujuan Yin; Minghui Lin; Junke Zheng; Bo O Zhou
Journal:  EMBO J       Date:  2018-07-23       Impact factor: 11.598

3.  Conversion of adult endothelium to immunocompetent haematopoietic stem cells.

Authors:  Raphael Lis; Charles C Karrasch; Michael G Poulos; Balvir Kunar; David Redmond; Jose G Barcia Duran; Chaitanya R Badwe; William Schachterle; Michael Ginsberg; Jenny Xiang; Arash Rafii Tabrizi; Koji Shido; Zev Rosenwaks; Olivier Elemento; Nancy A Speck; Jason M Butler; Joseph M Scandura; Shahin Rafii
Journal:  Nature       Date:  2017-05-17       Impact factor: 49.962

4.  Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization.

Authors:  Manuel Valiente; Karuna Ganesh; Ekrem Emrah Er; Yilong Zou; Saloni Agrawal; Jing Hu; Bailey Griscom; Marc Rosenblum; Adrienne Boire; Edi Brogi; Filippo G Giancotti; Melitta Schachner; Srinivas Malladi; Joan Massagué
Journal:  Nat Cell Biol       Date:  2018-07-23       Impact factor: 28.824

5.  Bone's dark side: mutated osteoblasts implicated in leukemia.

Authors:  Amir Schajnovitz; David T Scadden
Journal:  Cell Res       Date:  2014-03-04       Impact factor: 25.617

6.  Thyroid hormone receptor beta and NCOA4 regulate terminal erythrocyte differentiation.

Authors:  Xiaofei Gao; Hsiang-Ying Lee; Wenbo Li; Randall Jeffrey Platt; M Inmaculada Barrasa; Qi Ma; Russell R Elmes; Michael G Rosenfeld; Harvey F Lodish
Journal:  Proc Natl Acad Sci U S A       Date:  2017-09-01       Impact factor: 11.205

Review 7.  Myeloma and Bone Disease.

Authors:  Cristina Panaroni; Andrew J Yee; Noopur S Raje
Journal:  Curr Osteoporos Rep       Date:  2017-10       Impact factor: 5.096

8.  Functional Niche Competition Between Normal Hematopoietic Stem and Progenitor Cells and Myeloid Leukemia Cells.

Authors:  Chen Glait-Santar; Ronan Desmond; Xingmin Feng; Taha Bat; Jichun Chen; Elisabeth Heuston; Benjamin Mizukawa; James C Mulloy; David M Bodine; Andre Larochelle; Cynthia E Dunbar
Journal:  Stem Cells       Date:  2015-10-05       Impact factor: 6.277

9.  EBF1-deficient bone marrow stroma elicits persistent changes in HSC potential.

Authors:  Marta Derecka; Josip Stefan Herman; Pierre Cauchy; Senthilkumar Ramamoorthy; Ekaterina Lupar; Dominic Grün; Rudolf Grosschedl
Journal:  Nat Immunol       Date:  2020-02-17       Impact factor: 25.606

10.  Calcium-Infiltrated Biphasic Hydroxyapatite Scaffolds for Human Hematopoietic Stem Cell Culture.

Authors:  Qinghao Zhang; Jörg C Gerlach; Ian Nettleship; Eva Schmelzer
Journal:  Tissue Eng Part A       Date:  2018-06-04       Impact factor: 3.845

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