Literature DB >> 29502564

How Good Intentions Contributed to Bad Outcomes: The Opioid Crisis.

Teresa A Rummans1, M Caroline Burton2, Nancy L Dawson3.   

Abstract

The opioid crisis that exists today developed over the past 30 years. The reasons for this are many. Good intentions to improve pain and suffering led to increased prescribing of opioids, which contributed to misuse of opioids and even death. Following the publication of a short letter to the editor in a major medical journal declaring that those with chronic pain who received opioids rarely became addicted, prescriber attitude toward opioid use changed. Opioids were no longer reserved for treatment of acute pain or terminal pain conditions but now were used to treat any pain condition. Governing agencies began to evaluate doctors and hospitals on their control of patients' pain. Ultimately, reimbursement became tied to patients' perception of pain control. As a result, increasing amounts of opioids were prescribed, which led to dependence. When this occurred, patients sought more in the form of opioid prescriptions from providers or from illegal sources. Illegal, unregulated sources of opioids are now a factor in the increasing death rate from opioid overdoses. Stopping the opioid crisis will require the engagement of all, including health care providers, hospitals, the pharmaceutical industry, and federal and state government agencies.
Copyright © 2017 Mayo Foundation for Medical Education and Research. Published by Elsevier Inc. All rights reserved.

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Year:  2018        PMID: 29502564     DOI: 10.1016/j.mayocp.2017.12.020

Source DB:  PubMed          Journal:  Mayo Clin Proc        ISSN: 0025-6196            Impact factor:   7.616


  36 in total

1.  A Laboratory Session to Prepare Pharmacy Students to Manage the Opioid Crisis Situation.

Authors:  Krista L Donohoe; Archana Raghavan; Thuy T Tran; Fawaz M Alotaibi; Kacie E Powers; Laura M Frankart
Journal:  Am J Pharm Educ       Date:  2019-09       Impact factor: 2.047

2.  Insurance Companies Fighting the Peer Review Empire without any Validity: the Case for Addiction and Pain Modalities in the face of an American Drug Epidemic.

Authors:  K Blum; W Jacobs; E J Modestino; N DiNubile; D Baron; T McLaughlin; D Siwicki; I Elman; M Moran; E R Braverman; P K Thanos; R D Badgaiyan
Journal:  SEJ Surg Pain       Date:  2018-10-04

3.  Diabetic Gastroparesis.

Authors:  Adil E Bharucha; Yogish C Kudva; David O Prichard
Journal:  Endocr Rev       Date:  2019-10-01       Impact factor: 19.871

Review 4.  Chronic Constipation.

Authors:  Adil E Bharucha; Arnold Wald
Journal:  Mayo Clin Proc       Date:  2019-05-01       Impact factor: 7.616

5.  Structural basis for selective inhibition of human PKG Iα by the balanol-like compound N46.

Authors:  Liying Qin; Banumathi Sankaran; Sahar Aminzai; Darren E Casteel; Choel Kim
Journal:  J Biol Chem       Date:  2018-05-16       Impact factor: 5.157

6.  Circumstances of overdose among street-involved, opioid-injecting women: Drug, set, and setting.

Authors:  Janna Ataiants; Alexis M Roth; Silvana Mazzella; Stephen E Lankenau
Journal:  Int J Drug Policy       Date:  2020-02-18

Review 7.  Interdisciplinary Mitigation of Opioid Misuse in Musculoskeletal Patients.

Authors:  Ammar N Saigal; Henderson M Jones
Journal:  HSS J       Date:  2018-12-10

8.  HIV Physicians and Chronic Opioid Therapy: It's Time to Raise the Bar.

Authors:  Jennifer J Carroll; Jonathan Colasanti; Marlene C Lira; Carlos Del Rio; Jeffrey H Samet
Journal:  AIDS Behav       Date:  2019-04

9.  Genome-wide association study of phenotypes measuring progression from first cocaine or opioid use to dependence reveals novel risk genes.

Authors:  Richard Sherva; Congcong Zhu; Leah Wetherill; Howard J Edenberg; Emma Johnson; Louisa Degenhardt; Arpana Agrawal; Nicholas G Martin; Elliot Nelson; Henry R Kranzler; Joel Gelernter; Lindsay A Farrer
Journal:  Explor Med       Date:  2021-02-28

Review 10.  From Pharmacology to Physiology: Endocrine Functions of μ-Opioid Receptor Networks.

Authors:  Nikolai Jaschke; Sophie Pählig; Ying-Xian Pan; Lorenz C Hofbauer; Andy Göbel; Tilman D Rachner
Journal:  Trends Endocrinol Metab       Date:  2021-03-03       Impact factor: 12.015

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