Christina Tomei1, Sophie Lebel2, Christine Maheu3, Monique Lefebvre4, Cheryl Harris4. 1. School of Psychology, University of Ottawa, 136 Jean-Jacques-Lussier Private, Vanier Hall, Ottawa, ON, K1N 6N5, Canada. ctome085@uottawa.ca. 2. School of Psychology, University of Ottawa, 136 Jean-Jacques-Lussier Private, Vanier Hall, Ottawa, ON, K1N 6N5, Canada. 3. Ingram School of Nursing, McGill University, Montreal, QC, Canada. 4. Psychology Department, The Ottawa Hospital, Ottawa, ON, Canada.
Abstract
PURPOSE: Among cancer survivors, fear of cancer recurrence (FCR) is the most frequently reported unmet need. Despite this, research on psychosocial interventions that target FCR is limited. To address this gap, an individual cognitive-existential psychotherapy intervention for FCR was pilot tested via small-scale RCT. METHODS:Participants were recruited via study posters, healthcare professionals' referrals, and an electronic hospital database. Twenty-five female cancer survivors were randomized to experimental or wait-list control groups. Sessions included cognitive restructuring techniques, behavioral experiments, discussion of existential concerns, and relaxation exercises. Nineteen women completed the 6-week intervention and completed questionnaire packages at various time points. All participants completed self-administered questionnaires at pre-intervention (T1), post-intervention (T2), and at 3-month follow-up (T3). Participants in the control group also completed the same questionnaires, including at baseline (T0). RESULTS: Statistically significant results of between-within ANOVAs included time by condition interactions in the primary outcome measure of FCR and, for the experimental group participants, time by condition interactions in the secondary outcome measures of cancer-specific distress and uncertainty in illness. Statistically significant results of repeated measures ANOVAs included reductions in FCR, cancer-specific distress, uncertainty in illness, reassurance seeking, cognitive avoidance, and intolerance of uncertainty, as well as improvements in positive reinterpretation and growth, emotional coping, and quality of life (improved mental health), when compared to the control group. Most changes were maintained at 3-month follow-up. CONCLUSIONS: This intervention responds to a need for evidence-based individual modality interventions targeting quality of life in cancer survivors. Our results demonstrate preliminary promising results in addressing FCR in female cancer survivors. Future research could seek to replicate results with a larger sample. Further research is needed to test this intervention with patients of mixed cancer sites.
RCT Entities:
PURPOSE: Among cancer survivors, fear of cancer recurrence (FCR) is the most frequently reported unmet need. Despite this, research on psychosocial interventions that target FCR is limited. To address this gap, an individual cognitive-existential psychotherapy intervention for FCR was pilot tested via small-scale RCT. METHODS:Participants were recruited via study posters, healthcare professionals' referrals, and an electronic hospital database. Twenty-five female cancer survivors were randomized to experimental or wait-list control groups. Sessions included cognitive restructuring techniques, behavioral experiments, discussion of existential concerns, and relaxation exercises. Nineteen women completed the 6-week intervention and completed questionnaire packages at various time points. All participants completed self-administered questionnaires at pre-intervention (T1), post-intervention (T2), and at 3-month follow-up (T3). Participants in the control group also completed the same questionnaires, including at baseline (T0). RESULTS: Statistically significant results of between-within ANOVAs included time by condition interactions in the primary outcome measure of FCR and, for the experimental group participants, time by condition interactions in the secondary outcome measures of cancer-specific distress and uncertainty in illness. Statistically significant results of repeated measures ANOVAs included reductions in FCR, cancer-specific distress, uncertainty in illness, reassurance seeking, cognitive avoidance, and intolerance of uncertainty, as well as improvements in positive reinterpretation and growth, emotional coping, and quality of life (improved mental health), when compared to the control group. Most changes were maintained at 3-month follow-up. CONCLUSIONS: This intervention responds to a need for evidence-based individual modality interventions targeting quality of life in cancer survivors. Our results demonstrate preliminary promising results in addressing FCR in female cancer survivors. Future research could seek to replicate results with a larger sample. Further research is needed to test this intervention with patients of mixed cancer sites.
Entities:
Keywords:
Coping; Fear of cancer recurrence; Pilot study; Psychosocial interventions; Psychosocial oncology; Randomized controlled clinical trial
Authors: Eric Vachon; Ellen Krueger; Victoria L Champion; David A Haggstrom; David Cella; Andrea A Cohee Journal: Psychooncology Date: 2020-10-15 Impact factor: 3.894
Authors: Nina M Tauber; Mia S O'Toole; Andreas Dinkel; Jacqueline Galica; Gerry Humphris; Sophie Lebel; Christine Maheu; Gozde Ozakinci; Judith Prins; Louise Sharpe; Allan Ben Smith; Belinda Thewes; Sébastien Simard; Robert Zachariae Journal: J Clin Oncol Date: 2019-09-18 Impact factor: 44.544