| Literature DB >> 29495966 |
Lanping Xu1, Hu Chen2, Jing Chen3, Mingzhe Han4, He Huang5, Yongrong Lai6, Daihong Liu7, Qifa Liu8, Ting Liu9, Ming Jiang10, Hanyun Ren11, Yongping Song12, Zimin Sun13, Jianmin Wang14, Depei Wu15, Daobin Zhou16, Ping Zou17, Kaiyan Liu1, Xiaojun Huang18,19.
Abstract
Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is widely used to treat malignant hematological neoplasms and non-malignant hematological disorders. Approximately, 5000 allo-HSCT procedures are performed in China annually. Substantial progress has been made in haploidentical HSCT (HID-HSCT), pre-transplantation risk stratification, and donor selection in allo-HSCT, especially after the establishment of the "Beijing Protocol" HID-HSCT system. Transplant indications for selected subgroups in low-risk leukemia or severe aplastic anemia (SAA) differ from those in the Western world. These unique systems developed by Chinese doctors may inspire the refining of global clinical practice. We reviewed the efficacy of allo-HSCT practice from available Chinese studies on behalf of the HSCT workgroup of the Chinese Society of Hematology, Chinese Medical Association and compared these studies to the consensus or guideline outside China. We summarized the consensus on routine practices of all-HSCT in China and focused on the recommendations of indications, conditioning regimen, and donor selection.Entities:
Keywords: Allogeneic hematopoietic transplantation; China; Conditioning regimen; Consensus; Donor selection; Indication; Standard of care
Mesh:
Year: 2018 PMID: 29495966 PMCID: PMC5833104 DOI: 10.1186/s13045-018-0564-x
Source DB: PubMed Journal: J Hematol Oncol ISSN: 1756-8722 Impact factor: 17.388