Literature DB >> 31431695

Update of the "Beijing Protocol" haplo-identical hematopoietic stem cell transplantation.

Meng Lv1, Ying-Jun Chang1, Xiao-Jun Huang2,3.   

Abstract

As one of the three successful approaches for haplo-identical stem cell transplantation (haplo-SCT) in recent decades, "Beijing protocol" was based on immune tolerance induced by granulocyte colony-stimulating factor plus anti-thymocyte globulin, which included individualized conditioning regimens, novel donor selection algorithm, and risk-directed strategies for GvHD and relapse, etc. Haplo-HSCT following "Beijing protocol" demonstrated similar efficacy to HLA-matched SCT, which has become the predominant strategy for allogeneic SCT in China as well as inspiration for refinement of global practice. This review will focus on recent progressions and prospective of this approach in (1) the indications from hematological malignancies to non-malignant diseases; (2) microenvironment for hematopoietic recovery; and (3) improving T cells function.

Entities:  

Mesh：

Year:  2019        PMID： 31431695     DOI： 10.1038/s41409-019-0605-2

Source DB:  PubMed          Journal:  Bone Marrow Transplant        ISSN： 0268-3369            Impact factor:   5.483


  46 in total

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Review 2.  Haploidentical SCT: the mechanisms underlying the crossing of HLA barriers.

Authors:  Y-J Chang; X-J Huang
Journal:  Bone Marrow Transplant       Date:  2014-02-24       Impact factor: 5.483

3.  Haploidentical hematopoietic stem cell transplantation without in vitro T-cell depletion for the treatment of hematological malignancies.

Authors:  X-J Huang; D-H Liu; K-Y Liu; L-P Xu; H Chen; W Han; Y-H Chen; J-Z Wang; Z-Y Gao; Y-C Zhang; Q Jiang; H-X Shi; D-P Lu
Journal:  Bone Marrow Transplant       Date:  2006-08       Impact factor: 5.483

4.  Allo-HSCT for acute leukemia of ambiguous lineage in adults: the comparison between standard conditioning and intensified conditioning regimens.

Authors:  Qi-Fa Liu; Zhi-Ping Fan; Mei-Qing Wu; Jing Sun; Xiu-Li Wu; Dan Xu; Qian-Li Jiang; Yu Zhang; Fen Huang; Yong-Qiang Wei; Jie Zhao; Guo-Pan Yu; Fan-Yi Meng
Journal:  Ann Hematol       Date:  2012-12-30       Impact factor: 3.673

5.  A retrospective comparison of BU-fludarabine and BU-CY regimens in elderly patients or in patients with comorbidities who received unmanipulated haploidentical hematopoietic SCT.

Authors:  Y-Q Sun; L-P Xu; X-H Zhang; D-H Liu; H Chen; Y Wang; C-H Yan; J-Z Wang; F-R Wang; Y-Y Zhang; K-Y Liu; X-J Huang
Journal:  Bone Marrow Transplant       Date:  2015-01-19       Impact factor: 5.483

6.  Nonmyeloablative bone marrow transplantation from partially HLA-mismatched related donors using posttransplantation cyclophosphamide.

Authors:  P V O'Donnell; L Luznik; R J Jones; G B Vogelsang; M S Leffell; M Phelps; P Rhubart; K Cowan; S Piantados; E J Fuchs
Journal:  Biol Blood Marrow Transplant       Date:  2002       Impact factor: 5.742

7.  Total body irradiation and cyclophosphamide plus antithymocyte globulin regimen is well tolerated and promotes stable engraftment as a preparative regimen before T cell-replete haploidentical transplantation for acute leukemia.

Authors:  Haixia Fu; Lanping Xu; Daihong Liu; Kaiyan Liu; Xiaohui Zhang; Huan Chen; Yuhong Chen; Wei Han; Yu Wang; Jingzhi Wang; Fengrong Wang; Xiaojun Huang
Journal:  Biol Blood Marrow Transplant       Date:  2014-04-18       Impact factor: 5.742

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Authors:  Christopher G Kanakry; Ephraim J Fuchs; Leo Luznik
Journal:  Nat Rev Clin Oncol       Date:  2015-08-25       Impact factor: 66.675

Review 9.  Proceedings From the Fourth Haploidentical Stem Cell Transplantation Symposium (HAPLO2016), San Diego, California, December 1, 2016.

Authors:  Monzr M Al Malki; Richard Jones; Qing Ma; Dean Lee; Yair Reisner; Jeffrey S Miller; Peter Lang; Suradej Hongeng; Parameswaran Hari; Samuel Strober; Jianhua Yu; Richard Maziarz; Domenico Mavilio; Denis-Claude Roy; Chiara Bonini; Richard E Champlin; Ephraim J Fuchs; Stefan O Ciurea
Journal:  Biol Blood Marrow Transplant       Date:  2018-01-12       Impact factor: 5.742

10.  Early myeloid-derived suppressor cells (HLA-DR-/lowCD33+CD16-) expanded by granulocyte colony-stimulating factor prevent acute graft-versus-host disease (GVHD) in humanized mouse and might contribute to lower GVHD in patients post allo-HSCT.

Authors:  Ke Wang; Meng Lv; Ying-Jun Chang; Xiang-Yu Zhao; Xiao-Su Zhao; Yuan-Yuan Zhang; Yu-Qian Sun; Zhi-Dong Wang; Pan Suo; Yang Zhou; Dan Liu; Shu-Zhen Zhai; Yan Hong; Yu Wang; Xiao-Hui Zhang; Lan-Ping Xu; Kai-Yan Liu; Xiao-Jun Huang
Journal:  J Hematol Oncol       Date:  2019-03-18       Impact factor: 17.388
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  5 in total

1.  Prognosis and risk factors for central nervous system relapse after allogeneic hematopoietic stem cell transplantation in acute myeloid leukemia.

Authors:  Qi Chen; Xiao-Lu Zhu; Xin Zhao; Xiao Liu; Hai-Xia Fu; Yuan-Yuan Zhang; Yu-Hong Chen; Xiao-Dong Mo; Wei Han; Huan Chen; Chen-Hua Yan; Yu Wang; Ying-Jun Chang; Lan-Ping Xu; Xiao-Jun Huang; Xiao-Hui Zhang
Journal:  Ann Hematol       Date:  2021-01-02       Impact factor: 3.673

2.  Mesenchymal stromal cells as prophylaxis for graft-versus-host disease in haplo-identical hematopoietic stem cell transplantation recipients with severe aplastic anemia?-a systematic review and meta-analysis.

Authors:  Ruonan Li; Jingke Tu; Jingyu Zhao; Hong Pan; Liwei Fang; Jun Shi
Journal:  Stem Cell Res Ther       Date:  2021-02-04       Impact factor: 6.832

3.  G-CSF-Primed Peripheral Blood Stem Cell Haploidentical Transplantation Could Achieve Satisfactory Clinical Outcomes for Acute Leukemia Patients in the First Complete Remission: A Registered Study.

Authors:  Yan-Ru Ma; Xiaohui Zhang; Lanping Xu; Yu Wang; Chenhua Yan; Huan Chen; Yuhong Chen; Wei Han; Fengrong Wang; Jingzhi Wang; Kaiyan Liu; Xiaojun Huang; Xiaodong Mo
Journal:  Front Oncol       Date:  2021-03-15       Impact factor: 6.244

4.  Sequential Transplantation of Haploidentical Stem Cell and Unrelated Cord Blood With Using ATG/PTCY Increases Survival of Relapsed/Refractory Hematologic Malignancies.

Authors:  Hua Li; Xiaofan Li; Yiling Chen; Duihong Li; Xianling Chen; Zhijuan Zhu; Yiting Wang; Jiafu Huang; Ping Chen; Yuanzhong Chen; Nainong Li
Journal:  Front Immunol       Date:  2021-11-04       Impact factor: 7.561

5.  Comparable Outcomes in Acquired Severe Aplastic Anemia Patients With Haploidentical Donor or Matched Related Donor Transplantation: A Retrospective Single-Center Experience.

Authors:  QingYun Wang; HanYun Ren; ZeYin Liang; Wei Liu; Yue Yin; QingYa Wang; Qian Wang; YuHua Sun; WeiLin Xu; ZhiXiang Qiu; JinPing Ou; Na Han; Jing Wang; YuJun Dong; Yuan Li
Journal:  Front Med (Lausanne)       Date:  2022-01-24
  5 in total

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