Developing Microfluidic Sensing Devices Using 3D Printing.

This short perspective assesses the present landscape for desktop 3D printing to design and fabricate sensors, in particular, those associated with microfluidics and multiplexing. Lots of advanced devices have already been reported, and this article briefly surveys interesting achievements. Microfluidics can be designed and optimized faster and more easily on low cost desktop 3D printers that with competing methods. Rapid prototyping leads directly to a final (marketable) product fabricated on the same 3D printer. While resolution is not as good as lithographic approaches, very often channel and feature resolution on the order of 100 μm obtainable with SLA 3D printers is perfectly suitable for the desired sensing device. Two examples from our team's research are used to illustrate how using a 3D printer along with simple automation can reduce a complex microfluidic sensing procedure to a much simpler automated one. Future possibilities for sensor technology are discussed.