Literature DB >> 29490060

Actual versus 'ideal' antibiotic prescribing for common conditions in English primary care.

Koen B Pouwels1,2,3, F Christiaan K Dolk1,2, David R M Smith1, Julie V Robotham1, Timo Smieszek1,3.   

Abstract

Objectives: Previous work based on guidelines and expert opinion identified 'ideal' prescribing proportions-the overall proportion of consultations that should result in an antibiotic prescription-for common infectious conditions. Here, actual condition-specific prescribing proportions in primary care in England were compared with ideal prescribing proportions identified by experts.
Methods: All recorded consultations for common infectious conditions (cough, bronchitis, exacerbations of asthma or chronic obstructive pulmonary disease, sore throat, rhinosinusitis, otitis media, lower respiratory tract infection, upper respiratory tract infection, influenza-like illness, urinary tract infection, impetigo, acne, gastroenteritis) for 2013-15 were extracted from The Health Improvement Network (THIN) database. The proportions of consultations resulting in an antibiotic prescription were established, concentrating on acute presentations in patients without relevant comorbidities. These actual prescribing proportions were then compared with previously established 'ideal' proportions by condition.
Results: For most conditions, substantially higher proportions of consultations resulted in an antibiotic prescription than was deemed appropriate according to expert opinion. An antibiotic was prescribed in 41% of all acute cough consultations when experts advocated 10%. For other conditions the proportions were: bronchitis (actual 82% versus ideal 13%); sore throat (actual 59% versus ideal 13%); rhinosinusitis (actual 88% versus ideal 11%); and acute otitis media in 2- to 18-year-olds (actual 92% versus ideal 17%). Substantial variation between practices was found. Conclusions: This work has identified substantial overprescribing of antibiotics in English primary care, and highlights conditions where this is most pronounced, particularly in respiratory tract conditions.

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Year:  2018        PMID: 29490060      PMCID: PMC5890776          DOI: 10.1093/jac/dkx502

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN: 0305-7453            Impact factor:   5.790


  32 in total

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Review 2.  Antibiotics for acute otitis media in children.

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Journal:  Cochrane Database Syst Rev       Date:  2015-06-23

3.  Use of rapid diagnostic tests and choice of antibiotics in respiratory tract infections in primary healthcare--a 6-y follow-up study.

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4.  Prevalence of Inappropriate Antibiotic Prescriptions Among US Ambulatory Care Visits, 2010-2011.

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Authors:  Andrew Maguire; Betina T Blak; Mary Thompson
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6.  Bacterial prevalence and antimicrobial prescribing trends for acute respiratory tract infections.

Authors:  Matthew P Kronman; Chuan Zhou; Rita Mangione-Smith
Journal:  Pediatrics       Date:  2014-09-15       Impact factor: 7.124

7.  Continued high rates of antibiotic prescribing to adults with respiratory tract infection: survey of 568 UK general practices.

Authors:  Martin C Gulliford; Alex Dregan; Michael V Moore; Mark Ashworth; Tjeerd van Staa; Gerard McCann; Judith Charlton; Lucy Yardley; Paul Little; Lisa McDermott
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8.  Antibiotic prescribing in relation to diagnoses and consultation rates in Belgium, the Netherlands and Sweden: use of European quality indicators.

Authors:  Mia Tyrstrup; Alike van der Velden; Sven Engstrom; Geert Goderis; Sigvard Molstad; Theo Verheij; Samuel Coenen; Niels Adriaenssens
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9.  Variability of antibiotic prescribing in patients with chronic obstructive pulmonary disease exacerbations: a cohort study.

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10.  Non-Response to Antibiotic Treatment in Adolescents for Four Common Infections in UK Primary Care 1991-2012: A Retrospective, Longitudinal Study.

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Journal:  Antibiotics (Basel)       Date:  2016-07-04
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  54 in total

1.  Potential for reducing inappropriate antibiotic prescribing in English primary care.

Authors:  Timo Smieszek; Koen B Pouwels; F Christiaan K Dolk; David R M Smith; Susan Hopkins; Mike Sharland; Alastair D Hay; Michael V Moore; Julie V Robotham
Journal:  J Antimicrob Chemother       Date:  2018-02-01       Impact factor: 5.790

2.  Unnecessary antibiotic prescribing in a Canadian primary care setting: a descriptive analysis using routinely collected electronic medical record data.

Authors:  Kevin L Schwartz; Bradley J Langford; Nick Daneman; Branson Chen; Kevin A Brown; Warren McIsaac; Karen Tu; Elisa Candido; Jennie Johnstone; Valerie Leung; Jeremiah Hwee; Michael Silverman; Julie H C Wu; Gary Garber
Journal:  CMAJ Open       Date:  2020-05-07

3.  Defining the appropriateness and inappropriateness of antibiotic prescribing in primary care.

Authors:  David R M Smith; F Christiaan K Dolk; Koen B Pouwels; Morag Christie; Julie V Robotham; Timo Smieszek
Journal:  J Antimicrob Chemother       Date:  2018-02-01       Impact factor: 5.790

4.  Alterations of human skin microbiome and expansion of antimicrobial resistance after systemic antibiotics.

Authors:  Jay-Hyun Jo; Catriona P Harkins; Nicole H Schwardt; Jessica A Portillo; Matthew D Zimmerman; Claire L Carter; Md Amir Hossen; Cody J Peer; Eric C Polley; Véronique Dartois; William D Figg; Niki M Moutsopoulos; Julia A Segre; Heidi H Kong
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5.  Author response.

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6.  Does diagnostic testing always decrease antibiotics prescriptions?

Authors:  F Antoñanzas; C A Juárez-Castelló; R Rodríguez-Ibeas
Journal:  Eur J Health Econ       Date:  2022-08-03

7.  Association of Diet and Antimicrobial Resistance in Healthy U.S. Adults.

Authors:  Andrew Oliver; Zhengyao Xue; Yirui T Villanueva; Blythe Durbin-Johnson; Zeynep Alkan; Diana H Taft; Jinxin Liu; Ian Korf; Kevin D Laugero; Charles B Stephensen; David A Mills; Mary E Kable; Danielle G Lemay
Journal:  mBio       Date:  2022-05-10       Impact factor: 7.786

8.  Antibiotic use and serious complications following acute otitis media and acute sinusitis: a retrospective cohort study.

Authors:  Rebecca Cushen; Nick A Francis
Journal:  Br J Gen Pract       Date:  2020-03-26       Impact factor: 5.386

9.  Understanding the Context of High- and Low-Testosterone Prescribing Facilities in the Veterans Health Administration (VHA): a Qualitative Study.

Authors:  Guneet K Jasuja; Ryann L Engle; Avy Skolnik; Adam J Rose; Alexandra Male; Joel I Reisman; Barbara G Bokhour
Journal:  J Gen Intern Med       Date:  2019-09-11       Impact factor: 6.473

10.  Efficacy and safety of rapid tests to guide antibiotic prescriptions for sore throat.

Authors:  Jérémie F Cohen; Jean-Yves Pauchard; Nils Hjelm; Robert Cohen; Martin Chalumeau
Journal:  Cochrane Database Syst Rev       Date:  2020-06-04
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