| Literature DB >> 29467224 |
Abstract
Autophagy is a highly conserved, tightly regulated cellular process that degrades intracellular constituents via lysosomes. Autophagy mediates many normal cellular functions and is dysregulated in numerous diseases. This Thematic Series consists of five Minireviews that highlight selected topics of current autophagy research ranging from the molecular mechanisms and regulation of autophagy to the roles of autophagy in health and disease.Entities:
Keywords: ATG proteins; autophagy; lysosome; protein degradation; protein turnover; ubiquitin
Mesh:
Year: 2018 PMID: 29467224 PMCID: PMC5900753 DOI: 10.1074/jbc.TM118.002429
Source DB: PubMed Journal: J Biol Chem ISSN: 0021-9258 Impact factor: 5.157