| Literature DB >> 29462914 |
I-Lin Hsu1, Chia-Ming Chang2,3, Deng-Chi Yang4,5, Ya-Hui Chang6, Chia-Chun Li7, Susan C Hu8, Chung-Yi Li9,10.
Abstract
Hip fracture commonly results in considerable consequences in terms of disability, mortality, long-term institutional care and cost. Taiwan launched its universal health insurance coverage in 1995, which largely removes financial barriers to health care. This study aims to investigate whether socioeconomic inequality in one-year mortality exists among Taiwanese elderly people. This population-based cohort study included 193,158 elderly patients (≥65 years) admitted for hip fracture between 2000 and 2012. With over a one-year follow-up, 10.52% of the participants died from all causes. The mortality rate was low in the northern part of Taiwan and in urban and high-family-income areas. Multiple Poisson regression models further suggested that the level of >Q1-Q3 and >Q3-Max showed significantly reduced odds ratio of one-year mortality at 0.90 (95% confidence interval (CI), 0.87-0.93) and 0.77 (95% CI, 0.74-0.81), respectively, compared with that of the lowest family income level (i.e., Min.-Q1). Despite a monotonic decline in overall one-year mortality during the study period, socioeconomic inequality in one-year mortality rate remained evident. The annual percentage change in one-year mortality was higher (-2.86) in elderly people from families with high income (>Q3-Max.) than that for elderly patients from family with low income (Min.-Q1, -1.94). Accessibility, rather than affordability, to health care for hip fracture is probably responsible for the observed socioeconomic inequality.Entities:
Keywords: health inequality; hip fracture; mortality; socioeconomic status; urbanization
Mesh:
Year: 2018 PMID: 29462914 PMCID: PMC5858421 DOI: 10.3390/ijerph15020352
Source DB: PubMed Journal: Int J Environ Res Public Health ISSN: 1660-4601 Impact factor: 3.390
Characteristics of the study patients and risk of one-year mortality.
| Characteristics | No. of Patients a | One-Year Mortality | ||
|---|---|---|---|---|
| Number | % | |||
| Geographic area | ||||
| North | 77,375 (40.1) | 7547 | 9.75 | <0.0001 |
| Central | 51,095 (26.5) | 5743 | 11.24 | |
| South | 56,247 (29.1) | 6038 | 10.73 | |
| East | 7483 (3.9) | 906 | 12.11 | |
| Urbanization status | ||||
| Urban area | 65,254 (33.8) | 6469 | 9.91 | <0.0001 |
| Satellite area | 51,482 (26.7) | 5268 | 10.23 | |
| Rural area | 75,135 (38.9) | 8468 | 11.27 | |
| City/township median family annual income b | ||||
| Min.–Q1 | 42,374 (21.9) | 4974 | 11.74 | <0.0001 |
| >Q1–Q3 | 87,410 (45.3) | 9319 | 10.66 | |
| >Q3–Max. | 43,459 (22.5) | 4043 | 9.30 | |
| Patient-level characteristics | ||||
| Gender | ||||
| Female | 118,370 (61.3) | 10,134 | 8.56 | <0.0001 |
| Male | 74,748 (38.7) | 10,192 | 13.64 | |
| Age, years | ||||
| 65–74 | 48,321 (25.0) | 3494 | 7.23 | <0.0001 |
| 75–84 | 93,310 (48.3) | 9241 | 9.90 | |
| 85+ | 51,527 (26.7) | 7593 | 14.74 | |
| Comorbidity | ||||
| Dementia | 7515 (3.9) | 999 | 13.29 | <0.0001 |
| Stroke | 23,526 (12.2) | 2809 | 11.94 | <0.0001 |
| COPD c | 16,223 (8.4) | 2966 | 18.28 | <0.0001 |
| Heart failure | 13,060 (6.8) | 2773 | 21.23 | <0.0001 |
| Hospital-level characteristics | ||||
| Hospital accreditation level | ||||
| Medical center | 54,405 (28.2) | 5305 | 9.75 | <0.0001 |
| Regional hospital | 85,769 (44.4) | 8981 | 10.47 | |
| Local hospital | 52,978 (27.4) | 6042 | 11.40 | |
| Length of hospital stay d | ||||
| Min–Q1 | 51,974 (26.9) | 5269 | 10.14 | <0.0001 |
| Q1–Median | 45,679 (23.7) | 3385 | 7.41 | |
| Median–Q3 | 50,959 (26.4) | 4306 | 8.45 | |
| Q3–Max | 44,546 (23.1) | 7368 | 16.54 | |
| Mean ± SD | 10.34 ± 16.44 | |||
| Total | 193,158 (100.0) | 20,328 | 10.52 | |
a Inconsistency between the total population and population summed for individual variables was due to missing information. b Min., Q1, Q3, and Max. for family annual income was 10,000, 16,433, 20167, and 31,066 USD, respectively. c COPD, chronic obstructive pulmonary disease. d Min., Q1, Median, Q3, and Max. for length of hospital stay was 1, 6, 8, 11, and 240 days, respectively.
Odds ratios of one-year mortality in relation to patient- and hospital-level characteristics and residential city/township characteristics.
| Characteristics | Odds Ratio | ||
|---|---|---|---|
| Crude Estimate (95% CI) | Adjusted Estimate (95% CI) | ||
| Model 1 a | Model 2 b | ||
| Geographic area | |||
| North | 0.78 (0.73–0.84) | 0.86 (0.79–0.94) | 0.87 *** (0.80–0.94) |
| Central | 0.92 (0.85–0.99) | 0.96 (0.89–1.04) | 0.97 (0.90–1.05) |
| South | 0.87 (0.81–0.94) | 0.98 (0.91–1.07) | 0.99 (0.91–1.07) |
| East (Ref.) | 1.00 | 1.00 | 1.00 |
| Urbanization status | |||
| Urban area | 0.87 (0.84–0.90) | 1.04 (0.99–1.09) | 1.05 (1.00–1.10) |
| Satellite area | 0.90 (0.87–0.93) | 0.98 (0.94–1.03) | 1.00 (0.96–1.05) |
| Rural area (Ref.) | 1.00 | 1.00 | 1.00 |
| City/Township median family annual income | |||
| Min.–Q1 (Ref.) | 1.00 | 1.00 | 1.00 |
| >Q1–Q3 | 0.90 (0.87–0.93) | 0.91 (0.87–0.94) | 0.91 *** (0.87–0.95) |
| >Q3–Max. | 0.77 (0.74–0.81) | 0.80 (0.75–0.85) | 0.80 *** (0.75–0.85) |
| Gender | |||
| Female (Ref.) | 1.00 | 1.00 | 1.00 |
| Male | 1.69 (1.64–1.74) | 1.67 (1.62–1.72) | 1.67 *** (1.61–1.72) |
| Age, years | |||
| 65–74 (Ref.) | 1.00 | 1.00 | 1.00 |
| 75–84 | 1.41 (1.35–1.47) | 1.36 (1.31–1.42) | 1.37 *** (1.31–1.43) |
| ≥85 | 2.22 (2.13–2.31) | 2.18 (2.08–2.28) | 2.18 *** (2.08–2.28) |
| Comorbidity | |||
| Dementia | 1.32 (1.23–1.41) | 1.15 (1.06–1.23) | 1.12 ** (1.04–1.20) |
| Stroke | 1.18 (1.13–1.23) | 1.13 (1.08–1.18) | 1.10 *** (1.05–1.15) |
| COPD | 2.06 (1.97–2.15) | 1.49 (1.42–1.57) | 1.41 *** (1.34–1.48) |
| Heart failure | 2.50 (2.39–2.61) | 2.25 (2.15–2.37) | 2.11 *** (2.01–2.21) |
| Hospital accreditation level | |||
| Medical center | 1.00 | 1.00 | |
| Regional hospital | 1.08 (1.04–1.12) | 1.05 ** (1.01–1.10) | |
| Local hospital | 1.19 (1.15–1.24) | 1.14 *** (1.09–1.19) | |
| Length of hospital stay c | |||
| Min–Q1 | 1.00 | 1.00 | |
| Q1–Median | 0.71 (0.68–0.74) | 0.71 *** (0.67–0.74) | |
| Median–Q3 | 0.82 (0.78–0.85) | 0.79 *** (0.76–0.83) | |
| Q3–Max | 1.76 (1.69–1.82) | 1.59 *** (1.53–1.66) | |
a Min., Q1, Q3, and Max. for median family annual income was 10,000, 16,433, 20167, and 31,066 USD, respectively. b COPD, chronic obstructive pulmonary disease. c Min., Q1, Median, Q3, and Max. for length of hospital stay was 1, 6, 8, 11, and 240 days, respectively. *** p-value < 0.001; ** p-value < 0.01
Odds ratios of one-year mortality in relation to median family annual income levels according to a patient’s age.
| Age Groups, Years | City/Township Median Family Annual Income | Adjusted Odds Ratios (95%CI) |
|---|---|---|
| 65–74 | Min.–Q1 (Ref.) | 1.00 |
| >Q1–Q3 | 0.89 (0.80–0.98) | |
| >Q3–Max. | 0.84 (0.72–0.97) | |
| 75–84 | Min.–Q1 (Ref.) | 1.00 |
| >Q1–Q3 | 0.92 (0.87–0.98) | |
| >Q3–Max. | 0.79 (0.72–0.86) | |
| ≥85 | Min.–Q1 (Ref.) | 1.00 |
| >Q1–Q3 | 0.91 (0.85–0.97) | |
| >Q3–Max. | 0.80 (0.73–0.89) |
Figure 1(a) Secular trend in socioeconomic disparity of one-year mortality rate from 2000 to 2012. (b) Jointpoint regression models estimating the annual percent change across the study period.