Kei Harada1, Kosuke Kakumoto2, Shogo Oshikata2, Kozo Fukuyama2. 1. Department of Neurosurgery, Fukuoka Wajiro Hispital, 2-2-75, Wajirogaoka, Higashi-Ku, Fukuoka-city, Fukuoka, 811-0213, Japan. keihara@f-wajirohp.jp. 2. Department of Neurosurgery, Fukuoka Wajiro Hispital, 2-2-75, Wajirogaoka, Higashi-Ku, Fukuoka-city, Fukuoka, 811-0213, Japan.
Abstract
BACKGROUND: Carotid artery stenting (CAS) with proximal occlusion effectively prevent distal cerebral embolism by flow arrest at internal carotid artery (ICA); however, the method can expose antegrade flow at ICA due to incomplete flow arrest. The aim of this study was to identify predictors of antegrade flow during CAS with proximal protection. METHODS: We retrospectively analyzed clinical and angiographic data among 143 lesions treated with CAS with proximal protection by occluding the common carotid artery (CCA) and external carotid artery (ECA). Flow arrest or antegrade flow at ICA was confirmed by contrast injection during proximal protection. RESULTS: Antegrade flow at ICA was observed in 12 lesions (8.4%). Compared with lesions in which flow arrest of ICA was achieved, the diameter of the superior thyroid artery (STA) was significantly larger (2.4 ± 0.34 vs. 1.4 ± 0.68 mm, p < 0.001), and the rate of ECA branches other than the STA located 0-10 mm above the bifurcation was significantly higher (50 vs. 8.4%, p < 0.001). Results of multivariate analysis revealed that a diameter of the STA ≥ 2.3 mm (OR 44, 95% CI 8.1-237; p < 0.001) and ECA branches other than the STA located 0-10 mm above the bifurcation (OR 6.0, 95% CI 1.1-32; p = 0.036) were independent predictors of antegrade flow. CONCLUSIONS: Distal filter protection should be combined with proximal protection for the lesions with antegrade flow to prevent distal migration of the carotid debris.
BACKGROUND: Carotid artery stenting (CAS) with proximal occlusion effectively prevent distal cerebral embolism by flow arrest at internal carotid artery (ICA); however, the method can expose antegrade flow at ICA due to incomplete flow arrest. The aim of this study was to identify predictors of antegrade flow during CAS with proximal protection. METHODS: We retrospectively analyzed clinical and angiographic data among 143 lesions treated with CAS with proximal protection by occluding the common carotid artery (CCA) and external carotid artery (ECA). Flow arrest or antegrade flow at ICA was confirmed by contrast injection during proximal protection. RESULTS: Antegrade flow at ICA was observed in 12 lesions (8.4%). Compared with lesions in which flow arrest of ICA was achieved, the diameter of the superior thyroid artery (STA) was significantly larger (2.4 ± 0.34 vs. 1.4 ± 0.68 mm, p < 0.001), and the rate of ECA branches other than the STA located 0-10 mm above the bifurcation was significantly higher (50 vs. 8.4%, p < 0.001). Results of multivariate analysis revealed that a diameter of the STA ≥ 2.3 mm (OR 44, 95% CI 8.1-237; p < 0.001) and ECA branches other than the STA located 0-10 mm above the bifurcation (OR 6.0, 95% CI 1.1-32; p = 0.036) were independent predictors of antegrade flow. CONCLUSIONS: Distal filter protection should be combined with proximal protection for the lesions with antegrade flow to prevent distal migration of the carotid debris.
Authors: Daniel D Cavalcanti; Cassius Vinicius C Reis; Ricardo Hanel; Sam Safavi-Abbasi; Pushpa Deshmukh; Robert F Spetzler; Mark C Preul Journal: Neurosurgery Date: 2009-12 Impact factor: 4.654
Authors: Giuseppe Giugliano; Eugenio Stabile; Giancarlo Biamino; Giampaolo Petroni; Anna Sannino; Linda Brevetti; Armando Pucciarelli; Grigore Popusoi; Tullio Tesorio; Angelo Cioppa; Linda Cota; Luigi Salemme; Antonio Sorropago; Angelo Ausania; Giovanni Della Pietra; Arturo Fontanelli; Bruno Trimarco; Giovanni Esposito; Paolo Rubino Journal: JACC Cardiovasc Interv Date: 2014-10-15 Impact factor: 11.195