Literature DB >> 29434463

Initial Outcomes from a Multicenter Study Utilizing the Indego Powered Exoskeleton in Spinal Cord Injury.

Candy Tefertiller1, Kaitlin Hays1, Janell Jones1, Arun Jayaraman2, Clare Hartigan3, Tamara Bushnik4, Gail F Forrest5.   

Abstract

Objective: To assess safety and mobility outcomes utilizing the Indego powered exoskeleton in indoor and outdoor walking conditions with individuals previously diagnosed with a spinal cord injury (SCI).
Methods: We conducted a multicenter prospective observational cohort study in outpatient clinics associated with 5 rehabilitation hospitals. A convenience sample of nonambulatory individuals with SCI (N = 32) completed an 8-week training protocol consisting of walking training 3 times per week utilizing the Indego powered exoskeleton in indoor and outdoor conditions. Participants were also trained in donning/doffing the exoskeleton during each session. Safety measures such as adverse events (AEs) were monitored and reported. Time and independence with donning/doffing the exoskeleton as well as walking outcomes to include the 10-meter walk test (10MWT), 6-minute walk test (6MWT), Timed Up & Go test (TUG), and 600-meter walk test were evaluated from midpoint to final evaluations.
Results: All 32 participants completed the training protocol with limited device-related AEs, which resulted in no interruption in training. The majority of participants in this trial were able to don and doff the Indego independently. Final walking speed ranged from 0.19 to 0.55 m/s. Final average indoor and outdoor walking speeds among all participants were 0.37 m/s (SD = 0.08, 0.09, respectively), after 8 weeks of training. Significant (p < .05) improvements were noted between midpoint and final gait speeds in both indoor and outdoor conditions. Average walking endurance also improved among participants after training.
Conclusion: The Indego was shown to be safe for providing upright mobility to 32 individuals with SCIs who were nonambulatory. Improvements in speed and independence were noted with walking in indoor and outdoor conditions as well as with donning/doffing the exoskeleton.

Entities:  

Keywords:  ambulation; exoskeletons; gait; paraplegia; robotic devices; spinal cord injury; walking

Mesh:

Year:  2017        PMID: 29434463      PMCID: PMC5791927          DOI: 10.1310/sci17-00014

Source DB:  PubMed          Journal:  Top Spinal Cord Inj Rehabil        ISSN: 1082-0744


  18 in total

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6.  Mobility Outcomes Following Five Training Sessions with a Powered Exoskeleton.

Authors:  Clare Hartigan; Casey Kandilakis; Skyler Dalley; Mike Clausen; Edgar Wilson; Scott Morrison; Steven Etheridge; Ryan Farris
Journal:  Top Spinal Cord Inj Rehabil       Date:  2015-04-12

7.  Acute Cardiorespiratory and Metabolic Responses During Exoskeleton-Assisted Walking Overground Among Persons with Chronic Spinal Cord Injury.

Authors:  Nicholas Evans; Clare Hartigan; Casey Kandilakis; Elizabeth Pharo; Ismari Clesson
Journal:  Top Spinal Cord Inj Rehabil       Date:  2015-04-12

8.  Assessment of In-Hospital Walking Velocity and Level of Assistance in a Powered Exoskeleton in Persons with Spinal Cord Injury.

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9.  Improvements in speed-based gait classifications are meaningful.

Authors:  Arlene Schmid; Pamela W Duncan; Stephanie Studenski; Sue Min Lai; Lorie Richards; Subashan Perera; Samuel S Wu
Journal:  Stroke       Date:  2007-05-17       Impact factor: 7.914

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Authors:  Alberto Esquenazi; Mukul Talaty; Andrew Packel; Michael Saulino
Journal:  Am J Phys Med Rehabil       Date:  2012-11       Impact factor: 2.159

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Journal:  J Neuroeng Rehabil       Date:  2022-06-27       Impact factor: 5.208

6.  Kinematic Analysis of Exoskeleton-Assisted Community Ambulation: An Observational Study in Outdoor Real-Life Scenarios.

Authors:  Michela Goffredo; Paola Romano; Francesco Infarinato; Matteo Cioeta; Marco Franceschini; Daniele Galafate; Rebecca Iacopini; Sanaz Pournajaf; Marco Ottaviani
Journal:  Sensors (Basel)       Date:  2022-06-16       Impact factor: 3.847

7.  Trajectory Modulation for Impact Reducing of Lower-Limb Exoskeletons.

Authors:  Long Zhang; Guangkui Song; Chaobin Zou; Rui Huang; Hong Cheng; Dekun Hu
Journal:  Micromachines (Basel)       Date:  2022-05-24       Impact factor: 3.523

8.  An Assessment of Which Sociodemographic and Spinal Cord Injury-Specific Characteristics Influence Engagement With Experimental Therapies and Participation in Clinical Trials.

Authors:  Carlotta Pazzi; Clara Farrehi; Maclain Capron; Kim Anderson; Bonnie Richardson; Michael Stillman
Journal:  Top Spinal Cord Inj Rehabil       Date:  2021-11-17

9.  Effect of robotic exoskeleton gait training during acute stroke on functional ambulation.

Authors:  Kiran K Karunakaran; Sharon Gute; Gregory R Ames; Kathleen Chervin; Christina M Dandola; Karen J Nolan
Journal:  NeuroRehabilitation       Date:  2021       Impact factor: 2.138

10.  Movement therapy in advanced heart failure assisted by a lightweight wearable robot: a feasibility pilot study.

Authors:  Isabell Anna Just; Denis Fries; Sina Loewe; Volkmar Falk; Nikola Cesarovic; Frank Edelmann; Anna Feuerstein; Florian L Haufe; Michele Xiloyannis; Robert Riener; Felix Schoenrath
Journal:  ESC Heart Fail       Date:  2022-03-23
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