Literature DB >> 26364281

Acute Cardiorespiratory and Metabolic Responses During Exoskeleton-Assisted Walking Overground Among Persons with Chronic Spinal Cord Injury.

Nicholas Evans1,2, Clare Hartigan3, Casey Kandilakis3, Elizabeth Pharo1, Ismari Clesson3.   

Abstract

BACKGROUND: Lower extremity robotic exoskeleton technology is being developed with the promise of affording people with spinal cord injury (SCI) the opportunity to stand and walk. The mobility benefits of exoskeleton-assisted walking can be realized immediately, however the cardiorespiratory and metabolic benefits of this technology have not been thoroughly investigated.
OBJECTIVE: The purpose of this pilot study was to evaluate the acute cardiorespiratory and metabolic responses associated with exoskeleton-assisted walking overground and to determine the degree to which these responses change at differing walking speeds.
METHODS: Five subjects (4 male, 1 female) with chronic SCI (AIS A) volunteered for the study. Expired gases were collected during maximal graded exercise testing and two, 6-minute bouts of exoskeleton-assisted walking overground. Outcome measures included peak oxygen consumption (V̇O2peak), average oxygen consumption (V̇O2avg), peak heart rate (HRpeak), walking economy, metabolic equivalent of tasks for SCI (METssci), walk speed, and walk distance.
RESULTS: Significant differences were observed between walk-1 and walk-2 for walk speed, total walk distance, V̇O2avg, and METssci. Exoskeleton-assisted walking resulted in %V̇O2peak range of 51.5% to 63.2%. The metabolic cost of exoskeleton-assisted walking ranged from 3.5 to 4.3 METssci.
CONCLUSIONS: Persons with motor-complete SCI may be limited in their capacity to perform physical exercise to the extent needed to improve health and fitness. Based on preliminary data, cardiorespiratory and metabolic demands of exoskeleton-assisted walking are consistent with activities performed at a moderate intensity.

Entities:  

Keywords:  cardiovascular physiology; energy metabolism; exercise therapy; oxygen consumption; physical fitness; spinal cord injuries; walking

Mesh:

Year:  2015        PMID: 26364281      PMCID: PMC4568093          DOI: 10.1310/sci2102-122

Source DB:  PubMed          Journal:  Top Spinal Cord Inj Rehabil        ISSN: 1082-0744


  40 in total

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Journal:  Am J Respir Crit Care Med       Date:  2002-07-01       Impact factor: 21.405

Review 2.  A systematic review of functional ambulation outcome measures in spinal cord injury.

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Journal:  Spinal Cord       Date:  2007-10-09       Impact factor: 2.772

Review 3.  A compendium of energy costs of physical activities for individuals who use manual wheelchairs.

Authors:  Scott A Conger; David R Bassett
Journal:  Adapt Phys Activ Q       Date:  2011-10       Impact factor: 2.929

4.  A preliminary assessment of legged mobility provided by a lower limb exoskeleton for persons with paraplegia.

Authors:  Ryan J Farris; Hugo A Quintero; Spencer A Murray; Kevin H Ha; Clare Hartigan; Michael Goldfarb
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5.  American College of Sports Medicine position stand. Quantity and quality of exercise for developing and maintaining cardiorespiratory, musculoskeletal, and neuromotor fitness in apparently healthy adults: guidance for prescribing exercise.

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Journal:  Med Sci Sports Exerc       Date:  2011-07       Impact factor: 5.411

6.  Energy cost of physical activities in persons with spinal cord injury.

Authors:  Eileen G Collins; David Gater; Jenny Kiratli; Jolene Butler; Karla Hanson; W Edwin Langbein
Journal:  Med Sci Sports Exerc       Date:  2010-04       Impact factor: 5.411

7.  Metabolic responses to 4 different body weight-supported locomotor training approaches in persons with incomplete spinal cord injury.

Authors:  Jochen Kressler; Mark S Nash; Patricia A Burns; Edelle C Field-Fote
Journal:  Arch Phys Med Rehabil       Date:  2013-03-05       Impact factor: 3.966

Review 8.  Effect of spinal cord injury on the heart and cardiovascular fitness.

Authors:  W T Phillips; B J Kiratli; M Sarkarati; G Weraarchakul; J Myers; B A Franklin; I Parkash; V Froelicher
Journal:  Curr Probl Cardiol       Date:  1998-11       Impact factor: 5.200

Review 9.  Exercise recommendations for individuals with spinal cord injury.

Authors:  Patrick L Jacobs; Mark S Nash
Journal:  Sports Med       Date:  2004       Impact factor: 11.136

10.  Metabolic demand and muscle activation during different forms of bodyweight supported locomotion in men with incomplete SCI.

Authors:  Alyssa M Fenuta; Audrey L Hicks
Journal:  Biomed Res Int       Date:  2014-05-21       Impact factor: 3.411

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  33 in total

1.  Hemodynamic and cardiorespiratory responses to various arm cycling regimens in men with spinal cord injury.

Authors:  Todd A Astorino
Journal:  Spinal Cord Ser Cases       Date:  2019-01-15

Review 2.  Clinician-Focused Overview of Bionic Exoskeleton Use After Spinal Cord Injury.

Authors:  Anne E Palermo; Jennifer L Maher; Carsten Bach Baunsgaard; Mark S Nash
Journal:  Top Spinal Cord Inj Rehabil       Date:  2017

3.  Initial Outcomes from a Multicenter Study Utilizing the Indego Powered Exoskeleton in Spinal Cord Injury.

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Journal:  Top Spinal Cord Inj Rehabil       Date:  2017-11-20

4.  Safety and feasibility of exoskeleton-assisted walking during acute/sub-acute SCI in an inpatient rehabilitation facility: A single-group preliminary study.

Authors:  Andrew D Delgado; Miguel X Escalon; Thomas N Bryce; William Weinrauch; Stephanie J Suarez; Allan J Kozlowski
Journal:  J Spinal Cord Med       Date:  2019-10-11       Impact factor: 1.985

Review 5.  Robotic Rehabilitation and Spinal Cord Injury: a Narrative Review.

Authors:  Marwa Mekki; Andrew D Delgado; Adam Fry; David Putrino; Vincent Huang
Journal:  Neurotherapeutics       Date:  2018-07       Impact factor: 7.620

6.  Training Persons with Spinal Cord Injury to Ambulate Using a Powered Exoskeleton.

Authors:  Pierre K Asselin; Manuel Avedissian; Steven Knezevic; Stephen Kornfeld; Ann M Spungen
Journal:  J Vis Exp       Date:  2016-06-16       Impact factor: 1.355

7.  Exoskeleton Training May Improve Level of Physical Activity After Spinal Cord Injury: A Case Series.

Authors:  Ashraf S Gorgey; Rodney Wade; Ryan Sumrell; Lynette Villadelgado; Refka E Khalil; Timothy Lavis
Journal:  Top Spinal Cord Inj Rehabil       Date:  2017-05-04

8.  Feasibility of robotic exoskeleton ambulation in a C4 person with incomplete spinal cord injury: a case report.

Authors:  Robert M Lester; Ashraf S Gorgey
Journal:  Spinal Cord Ser Cases       Date:  2018-04-27

9.  Exoskeleton-assisted walking improves pulmonary function and walking parameters among individuals with spinal cord injury: a randomized controlled pilot study.

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Journal:  J Neuroeng Rehabil       Date:  2021-05-24       Impact factor: 4.262

Review 10.  The Effects of Powered Exoskeleton Gait Training on Cardiovascular Function and Gait Performance: A Systematic Review.

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