Literature DB >> 29429035

Inhibitory effect of the green tea molecule EGCG against dengue virus infection.

Muhareva Raekiansyah1, Corazon C Buerano1,2, Mark Anthony D Luz1, Kouichi Morita3.   

Abstract

Dengue virus (DENV) infection is a major public health problem worldwide; however, specific antiviral drugs against it are not available. Hence, identifying effective antiviral agents for the prevention of DENV infection is important. In this study, we showed that the reportedly highly biologically active green-tea component epigallocatechin gallate (EGCG) inhibited dengue virus infection regardless of infecting serotype, but no or minimal inhibition was observed with other flaviviruses, including Japanese encephalitis virus, yellow fever virus, and Zika virus. EGCG exerted its antiviral effect mainly at the early stage of infection, probably by interacting directly with virions to prevent virus infection. Our results suggest that EGCG specifically targets DENV and might be used as a lead structure to develop an antiviral drug for use against the virus.

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Year:  2018        PMID： 29429035     DOI： 10.1007/s00705-018-3769-y

Source DB:  PubMed          Journal:  Arch Virol        ISSN： 0304-8608            Impact factor:   2.574


  16 in total

Review 1.  Antiviral Mechanism of Action of Epigallocatechin-3-O-gallate and Its Fatty Acid Esters.

Authors:  Kunihiro Kaihatsu; Miyuki Yamabe; Yasuhito Ebara
Journal:  Molecules       Date:  2018-09-27       Impact factor: 4.411

Review 2.  Current and Promising Antivirals Against Chikungunya Virus.

Authors:  Friederike I L Hucke; Joachim J Bugert
Journal:  Front Public Health       Date:  2020-12-15

Review 3.  Antiviral Role of Phenolic Compounds against Dengue Virus: A Review.

Authors:  Vanessa Loaiza-Cano; Laura Milena Monsalve-Escudero; Carlos da Silva Maia Bezerra Filho; Marlen Martinez-Gutierrez; Damião Pergentino de Sousa
Journal:  Biomolecules       Date:  2020-12-24

Review 4.  The Relevance of Complementary and Integrative Medicine in the COVID-19 Pandemic: A Qualitative Review of the Literature.

Authors:  Georg Seifert; Michael Jeitler; Rainer Stange; Andreas Michalsen; Holger Cramer; Benno Brinkhaus; Tobias Esch; Annette Kerckhoff; Anna Paul; Michael Teut; Pirus Ghadjar; Jost Langhorst; Thomas Häupl; Vijay Murthy; Christian S Kessler
Journal:  Front Med (Lausanne)       Date:  2020-12-11

Review 5.  Demystifying therapeutic potential of medicinal plants against chikungunya virus.

Authors:  Sukender Kumar; Chanchal Garg; Samander Kaushik; Harpal Singh Buttar; Munish Garg
Journal:  Indian J Pharmacol       Date:  2021 Sep-Oct       Impact factor: 1.200

6.  Previously published ethno-pharmacological reports reveal the potentiality of plants and plant-derived products used as traditional home remedies by Bangladeshi COVID-19 patients to combat SARS-CoV-2.

Authors:  A T M Rafiqul Islam; Jannatul Ferdousi; Md Shahinozzaman
Journal:  Saudi J Biol Sci       Date:  2021-07-17       Impact factor: 4.219

Review 7.  A Review of the Ongoing Research on Zika Virus Treatment.

Authors:  Suely da Silva; Daniel Oliveira Silva Martins; Ana Carolina Gomes Jardim
Journal:  Viruses       Date:  2018-05-14       Impact factor: 5.048

Review 8.  Can phytotherapy with polyphenols serve as a powerful approach for the prevention and therapy tool of novel coronavirus disease 2019 (COVID-19)?

Authors:  Emile Levy; Edgard Delvin; Valérie Marcil; Schohraya Spahis
Journal:  Am J Physiol Endocrinol Metab       Date:  2020-08-05       Impact factor: 4.310

9.  Therapeutic Potential of EGCG, a Green Tea Polyphenol, for Treatment of Coronavirus Diseases.

Authors:  Junsoo Park; Rackhyun Park; Minsu Jang; Yea-In Park
Journal:  Life (Basel)       Date:  2021-03-04

Review 10.  Dengue Virus Infection: A Tale of Viral Exploitations and Host Responses.

Authors:  Nikita Nanaware; Anwesha Banerjee; Satarupa Mullick Bagchi; Parikshit Bagchi; Anupam Mukherjee
Journal:  Viruses       Date:  2021-09-30       Impact factor: 5.048
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