Steven A Rosenberg1, Eric J Moody1, Li-Ching Lee2, Carolyn DiGuiseppi3, Gayle C Windham4, Lisa D Wiggins5, Laura A Schieve5, Caroline M Ledbetter3, Susan E Levy6, Lisa Blaskey6, Lisa Young6, Pilar Bernal7, Cordelia R Rosenberg1, M Daniele Fallin8. 1. School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado. 2. Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland. 3. Colorado School of Public Health, University of Colorado Anschutz Medical Campus, Aurora, Colorado. 4. California Department of Public Health, Richmond, California. 5. National Center on Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, Atlanta, Georgia. 6. Perelman School of Medicine at University of Pennsylvania, Center for Autism Research, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. 7. Autism Spectrum Disorders Center, San Jose Medical Center, Kaiser Permanente Northern California, San Jose, California. 8. Department of Mental Health and Wendy Klag Center for Autism and Developmental Disabilities, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, Maryland.
Abstract
This study examined the effect of demographic factors on Social Communication Questionnaire (SCQ) scores in children aged 30-68 months. Diagnoses of ASD were made after a gold standard evaluation that included the Autism Diagnostic Observation Schedule (ADOS), and the Autism Diagnostic Interview Revised (ADI-R). The relationship of demographic variables to SCQ scores was compared in two source populations: (a) children recruited from clinical and educational sources serving children who have ASD or other developmental disorders (CE) and (b) children recruited from birth certificates to represent the general population (BC). The impact of the demographic variables-child sex, child age, maternal language, maternal ethnicity, maternal education, maternal race, and household income-on total SCQ score were studied to examine their impact on the SCQ's performance. Demographic factors predicting the SCQ total score were used to generate ROCs. Factors that had a significant influence on SCQ performance were identified by examining the area under the ROCs. Optimal SCQ cut-points were generated for significant factors using the Youden's Index. Overall male sex, lower household income, lower maternal education and Black race predicted higher SCQ scores. In this sample, the most common optimum value for the SCQ cut-point across the different sociodemographic groups was 11. Autism Res 2018, 11: 695-706.
This study examined the effect of demographic factors on Social Communication Questionnaire (SCQ) scores in children aged 30-68 months. Diagnoses of ASD were made after a gold standard evaluation that included the Autism Diagnostic Observation Schedule (ADOS), and the Autism Diagnostic Interview Revised (ADI-R). The relationship of demographic variables to SCQ scores was compared in two source populations: (a) children recruited from clinical and educational sources serving children who have ASD or other developmental disorders (CE) and (b) children recruited from birth certificates to represent the general population (BC). The impact of the demographic variables-child sex, child age, maternal language, maternal ethnicity, maternal education, maternal race, and household income-on total SCQ score were studied to examine their impact on the SCQ's performance. Demographic factors predicting the SCQ total score were used to generate ROCs. Factors that had a significant influence on SCQ performance were identified by examining the area under the ROCs. Optimal SCQ cut-points were generated for significant factors using the Youden's Index. Overall male sex, lower household income, lower maternal education and Black race predicted higher SCQ scores. In this sample, the most common optimum value for the SCQ cut-point across the different sociodemographic groups was 11. Autism Res 2018, 11: 695-706.
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