| Literature DB >> 29419631 |
Ryan P McLynn1, Taylor D Ottesen, Nathaniel T Ondeck, Jonathan J Cui, Lee E Rubin, Jonathan N Grauer.
Abstract
BACKGROUND: The Rothman Index is a comprehensive measure of overall patient status in the inpatient setting already in use at many medical centers. It ranges from 100 (best score) to -91 (worst score) and is calculated based on 26 variables encompassing vital signs, routine laboratory values, and organ system assessments from nursing rounds from the electronic medical record. Past research has shown an association of Rothman Index with complications, readmission, and death in certain populations, but it has not been evaluated in geriatric patients with hip fractures, a potentially vulnerable patient population. QUESTIONS/PURPOSES: (1) Is there an association between Rothman Index scores and postdischarge adverse events in a population aged 65 years and older with hip fractures? (2) What is the discriminative ability of Rothman Index scores in determining which patients will or will not experience these adverse events? (3) Are there Rothman Index thresholds associated with increased incidence of postdischarge adverse outcomes?Entities:
Mesh:
Year: 2018 PMID: 29419631 PMCID: PMC5916609 DOI: 10.1007/s11999.0000000000000186
Source DB: PubMed Journal: Clin Orthop Relat Res ISSN: 0009-921X Impact factor: 4.176
Variables contributing to the Rothman Index
Demographics
Incidence of adverse events
Fig. 1The distribution of the lowest Rothman Index scores from the patient cohort at the time of their hospital discharges is shown.
Fig. 2The distribution of latest Rothman Index scores from the patient cohort at the time of their hospital discharges is shown.
Multivariate regression for association with adverse events
Fig. 3 A-C(A) The incidence of any postdischarge adverse event by lowest Rothman Index score with locally weighted scatterplot smoothing trend line is shown. The horizontal line indicates upper 95% CI of cohort any adverse event rate (22.0%). The arrow signifies the point where the trend line intersects the upper 95% CI such that lower Rothman Index values are experiencing a significantly greater rate of any adverse event; this corresponds to a Rothman Index of 35 based on the rounding to the nearest five described in the text. (B) The incidence of postdischarge major adverse event by lowest Rothman Index score is shown with a locally weighted scatterplot smoothing trend line. The horizontal line indicates upper 95% CI of cohort readmission rate (12.6%). The arrow signifies the point where the trend line intersects the upper 95% CI such that lower Rothman Index values are experiencing a significantly greater readmission rate; this corresponds to a Rothman Index of 35 based on the rounding to the nearest five described in the text. (C) The mortality rate by lowest Rothman Index score is shown with a locally weighted scatterplot smoothing trend line. The horizontal line indicates upper 95% CI of cohort readmission rate (6.1%). The arrow signifies the point where the trend line intersects upper 95% CI such that lower Rothman Index values are experiencing a significantly greater readmission rate; this corresponds to a Rothman Index of 35 based on the rounding to the nearest five described in the text.
Fig. 4 A-C(A) The incidence of postdischarge any adverse event by latest Rothman Index score is shown with a locally weighted scatterplot smoothing trend line. The horizontal line indicates upper 95% CI of cohort any adverse event rate (22.0%). The arrow signifies the point where the trend line intersects upper 95% CI such that lower Rothman Index values are experiencing a significantly greater rate of any adverse event; this corresponds to a Rothman Index of 55 based on the rounding to the nearest five described in the text. (B) The incidence of postdischarge major adverse event by latest Rothman Index score is shown with locally weighted scatterplot smoothing trend line. The horizontal line indicates upper 95% CI of the cohort readmission rate (12.6%). The arrow signifies the point where the trend line intersects upper 95% CI such that lower Rothman Index values are experiencing a significantly greater readmission rate; this corresponds to a Rothman Index of 55 based on the rounding to the nearest five described in the text. (C) The mortality rate by latest Rothman Index score is shown with a locally weighted scatterplot smoothing trend line. The horizontal line indicates upper 95% CI of cohort readmission rate (6.1%). The arrow signifies the point where the trend line intersects upper 95% CI such that lower Rothman Index values are experiencing a significantly greater readmission rate; this corresponds to a Rothman Index of 55 based on the rounding to the nearest five described in the text.
Receiver operating characteristic curve analysis of postdischarge adverse events