Literature DB >> 29414467

Continuous functionally graded porous titanium scaffolds manufactured by selective laser melting for bone implants.

Changjun Han1, Yan Li1, Qian Wang1, Shifeng Wen1, Qingsong Wei2, Chunze Yan3, Liang Hao4, Jie Liu1, Yusheng Shi1.   

Abstract

A significant requirement for a bone implant is to replicate the functional gradient across the bone to mimic the localization change in stiffness. In this work, continuous functionally graded porous scaffolds (FGPSs) based on the Schwartz diamond unit cell with a wide range of graded volume fraction were manufactured by selective laser melting (SLM). The micro-topology, strut dimension characterization and effect of graded volume fraction on the mechanical properties of SLM-processed FGPSs were systematically investigated. The micro-topology observations indicate that diamond FGPSs with a wide range of graded volume fraction from 7.97% to 19.99% were fabricated without any defects, showing a good geometric reproduction of the original designs. The dimensional characterization demonstrates the capability of SLM in manufacturing titanium diamond FGPSs with the strut size of 483-905µm. The elastic modulus and yield strength of the titanium diamond FGPSs can be tailored in the range of 0.28-0.59GPa and 3.79-17.75MPa respectively by adjusting the graded volume fraction, which are comparable to those of the cancellous bone. The mathematical relationship between the graded porosity and compression properties of a FGPS was revealed. Furthermore, two equations based on the Gibson and Ashby model have been established to predict the modulus and yield strength of SLM-processed diamond FGPSs. Compared to homogeneous diamond porous scaffolds, FGPSs provide a wide range of mutative pore size and porosity, which are potential to be tailored to optimize the pore space for bone tissue growth. The findings provide a basis of new methodologies to design and manufacture superior graded scaffolds for bone implant applications.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Keywords:  Functionally graded porous scaffold; Graded volume fraction; Mechanical properties; Micro-topology; Selective laser melting

Mesh:

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Year:  2018        PMID: 29414467     DOI: 10.1016/j.jmbbm.2018.01.013

Source DB:  PubMed          Journal:  J Mech Behav Biomed Mater        ISSN: 1878-0180


  21 in total

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Review 2.  Additively manufactured metallic biomaterials.

Authors:  Elham Davoodi; Hossein Montazerian; Anooshe Sadat Mirhakimi; Masoud Zhianmanesh; Osezua Ibhadode; Shahriar Imani Shahabad; Reza Esmaeilizadeh; Einollah Sarikhani; Sahar Toorandaz; Shima A Sarabi; Rohollah Nasiri; Yangzhi Zhu; Javad Kadkhodapour; Bingbing Li; Ali Khademhosseini; Ehsan Toyserkani
Journal:  Bioact Mater       Date:  2021-12-30

3.  Functionally graded additive manufacturing for orthopedic applications.

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Journal:  J Orthop       Date:  2022-07-03

4.  Advances in Laser Additive Manufacturing of Ti-Nb Alloys: From Nanostructured Powders to Bulk Objects.

Authors:  Margarita A Khimich; Konstantin A Prosolov; Tatiana Mishurova; Sergei Evsevleev; Xavier Monforte; Andreas H Teuschl; Paul Slezak; Egor A Ibragimov; Alexander A Saprykin; Zhanna G Kovalevskaya; Andrey I Dmitriev; Giovanni Bruno; Yurii P Sharkeev
Journal:  Nanomaterials (Basel)       Date:  2021-04-29       Impact factor: 5.076

5.  Functionally Graded Scaffolds with Programmable Pore Size Distribution Based on Triply Periodic Minimal Surface Fabricated by Selective Laser Melting.

Authors:  Xueyong Zhou; Yuan Jin; Jianke Du
Journal:  Materials (Basel)       Date:  2020-11-09       Impact factor: 3.623

Review 6.  Challenges on optimization of 3D-printed bone scaffolds.

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Journal:  Biomed Eng Online       Date:  2020-09-03       Impact factor: 2.819

7.  Physical-Mechanical Characteristics and Microstructure of Ti6Al7Nb Lattice Structures Manufactured by Selective Laser Melting.

Authors:  Cosmin Cosma; Igor Drstvensek; Petru Berce; Simon Prunean; Stanisław Legutko; Catalin Popa; Nicolae Balc
Journal:  Materials (Basel)       Date:  2020-09-16       Impact factor: 3.623

8.  Additively Manufactured Continuous Cell-Size Gradient Porous Scaffolds: Pore Characteristics, Mechanical Properties and Biological Responses In Vitro.

Authors:  Fei Liu; Qichun Ran; Miao Zhao; Tao Zhang; David Z Zhang; Zuqiang Su
Journal:  Materials (Basel)       Date:  2020-06-05       Impact factor: 3.623

9.  In Vitro Bioactivity and Biocompatibility of Bio-Inspired Ti-6Al-4V Alloy Surfaces Modified by Combined Laser Micro/Nano Structuring.

Authors:  Chen Li; Yong Yang; Lijun Yang; Zhen Shi; Pengfei Yang; Guanghua Cheng
Journal:  Molecules       Date:  2020-03-25       Impact factor: 4.411

10.  Design and performance evaluation of additively manufactured composite lattice structures of commercially pure Ti (CP-Ti).

Authors:  Wei Xu; Aihua Yu; Xin Lu; Maryam Tamaddon; Mengdi Wang; Jiazhen Zhang; Jianliang Zhang; Xuanhui Qu; Chaozong Liu; Bo Su
Journal:  Bioact Mater       Date:  2020-11-07
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