Özgül Özgan Çelikel1, Özlem Doğan2, Nurkan Aksoy3. 1. Gynecology and Obstetrics Clinic, Yenimahalle Training and Research Hospital, Yildirim Beyazıt University, Ankara, Turkey. 2. Department of Biochemistry, Ankara University Faculty of Medicine, Ankara, Turkey. 3. Department of Biochemistry, Yenimahalle Training and Research Hospital, Yildirim Beyazıt University, Ankara, Turkey.
Abstract
BACKROUND: The relationship between maternal zinc level and birth weight, birth week, delivery type, garvida, maternal age, etc., contribute to diagnosis and clinical follow-up. METHOD: Multivariate investigated for data of 275 patients were obtained during their pregnancy periods until birth. 3 cc blood samples were centrifuged for 15 minutes at 2500 g within a period of 30 minutes and were stored at -80°C until the time of analysis. The zinc levels of the patients were found to be within the range of 49-129 μg/dL. Patients were divided into 8 groups according to their zinc levels (49-59, 60-69, …, 120-129) and the relationships of zinc level with the parameters related to the mode of delivery, week of delivery, birth weight, age, early membrane rupture, live-stillbirth, and gravid were statistically analyzed to determine differences between the groups. RESULTS: There was a significant difference between the live births and stillbirths with a 95% confidence level regarding the zinc level. The zinc level affected the live-stillbirth status; patients with a zinc level of 49-59 μg/dL had stillbirths, the live birth rate for 59-69 μg/dL was approximately 50%, whereas it was approximately 88% for in the patients with a zinc level of 109-119 μg/dL. All patients with a zinc level of 119 μg/dL and above had live births. CONCLUSION: Based on the results of this study, it is suggested that zinc supplementation may be an appropriate treatment for the pregnant women with low zinc levels to provide the realization of live births.
BACKROUND: The relationship between maternal zinc level and birth weight, birth week, delivery type, garvida, maternal age, etc., contribute to diagnosis and clinical follow-up. METHOD: Multivariate investigated for data of 275 patients were obtained during their pregnancy periods until birth. 3 cc blood samples were centrifuged for 15 minutes at 2500 g within a period of 30 minutes and were stored at -80°C until the time of analysis. The zinc levels of the patients were found to be within the range of 49-129 μg/dL. Patients were divided into 8 groups according to their zinc levels (49-59, 60-69, …, 120-129) and the relationships of zinc level with the parameters related to the mode of delivery, week of delivery, birth weight, age, early membrane rupture, live-stillbirth, and gravid were statistically analyzed to determine differences between the groups. RESULTS: There was a significant difference between the live births and stillbirths with a 95% confidence level regarding the zinc level. The zinc level affected the live-stillbirth status; patients with a zinc level of 49-59 μg/dL had stillbirths, the live birth rate for 59-69 μg/dL was approximately 50%, whereas it was approximately 88% for in the patients with a zinc level of 109-119 μg/dL. All patients with a zinc level of 119 μg/dL and above had live births. CONCLUSION: Based on the results of this study, it is suggested that zinc supplementation may be an appropriate treatment for the pregnant women with low zinc levels to provide the realization of live births.