Literature DB >> 29387919

Extinction times in the subcritical stochastic SIS logistic epidemic.

Graham Brightwell1, Thomas House2, Malwina Luczak3.   

Abstract

Many real epidemics of an infectious disease are not straightforwardly super- or sub-critical, and the understanding of epidemic models that exhibit such complexity has been identified as a priority for theoretical work. We provide insights into the near-critical regime by considering the stochastic SIS logistic epidemic, a well-known birth-and-death chain used to model the spread of an epidemic within a population of a given size N. We study the behaviour of the process as the population size N tends to infinity. Our results cover the entire subcritical regime, including the "barely subcritical" regime, where the recovery rate exceeds the infection rate by an amount that tends to 0 as [Formula: see text] but more slowly than [Formula: see text]. We derive precise asymptotics for the distribution of the extinction time and the total number of cases throughout the subcritical regime, give a detailed description of the course of the epidemic, and compare to numerical results for a range of parameter values. We hypothesise that features of the course of the epidemic will be seen in a wide class of other epidemic models, and we use real data to provide some tentative and preliminary support for this theory.

Entities:  

Keywords:  Birth-and-death chain; Near-critical epidemic; Stochastic SIS logistic epidemic; Time to extinction

Mesh:

Year:  2018        PMID: 29387919     DOI: 10.1007/s00285-018-1210-5

Source DB:  PubMed          Journal:  J Math Biol        ISSN: 0303-6812            Impact factor:   2.164


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