| Literature DB >> 29385926 |
Jacquelyn MacDonell1,2, Niravkumar Patel3, Sebastian Rubino1,2, Goutam Ghoshal4, Gregory Fischer3, E Clif Burdette4, Roy Hwang1, Julie G Pilitsis1,2.
Abstract
Currently, treatment of brain tumors is limited to resection, chemotherapy, and radiotherapy. Thermal ablation has been recently explored. High-intensity focused ultrasound (HIFU) is being explored as an alternative. Specifically, the authors propose delivering HIFU internally to the tumor with an MRI-guided robotic assistant (MRgRA). The advantage of the authors' interstitial device over external MRI-guided HIFU (MRgHIFU) is that it allows for conformal, precise ablation and concurrent tissue sampling. The authors describe their workflow for MRgRA HIFU delivery.Entities:
Keywords: DOF = degrees of freedom; GBM = glioblastoma; HIFU = high-intensity focused ultrasound; LITT = laser interstitial thermal therapy; MRI guided; MRIT = MRI thermometry; MRgHIFU = MRI-guided HIFU; MRgRA = MRI-guided robot assistant; SRS = stereotactic radiosurgery; brain tumor; high-intensity focused ultrasound; neural ablation
Mesh：
Year: 2018 PMID： 29385926 PMCID： PMC5907801 DOI： 10.3171/2017.11.FOCUS17613
Source DB: PubMed Journal: Neurosurg Focus ISSN： 1092-0684 Impact factor: 4.047