Literature DB >> 29382579

Preparation and immunological activity of polysaccharides and their derivatives.

Fang Chen1, Gangliang Huang2.   

Abstract

Polysaccharide is a kind of natural macromolecule polymer, which is widely existed in animals, plants and microorganisms, has a variety of biological activities, such as anti-tumor, anti-virus, anti-oxidation and immune regulation. Polysaccharides can affect macrophages, cells and other immune cells to improve the body's immune function, and have no toxic and side effects on normal cells, which make the polysaccharides receive widespread attention. In recent years, studies have shown that structural modification of polysaccharides can improve the immunological activity of polysaccharides. The common chemical modifications are sulfation, carboxymethylation, acetylation, phosphorylation, and so on. The chemical modification of polysaccharides and the immunomodulation of polysaccharides and polysaccharide derivatives were analyzed and discussed.
Copyright © 2018 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Chemical modification; Immunological activity; Polysaccharides

Mesh:

Substances:

Year:  2018        PMID: 29382579     DOI: 10.1016/j.ijbiomac.2018.01.169

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN: 0141-8130            Impact factor:   6.953


  25 in total

1.  Characterization of polysaccharides from Tetrastigma hemsleyanum Diels et Gilg Roots and their effects on antioxidant activity and H2O2-induced oxidative damage in RAW 264.7 cells.

Authors:  Qi Huang; Wen He; Ilkhomjon Khudoyberdiev; Chun-Lin Ye
Journal:  BMC Chem       Date:  2021-02-05

2.  A NIR fluorescence probe for monitoring Cys upregulation induced by balsam pear polysaccharide and imaging in zebrafish.

Authors:  Qiaofang Qi; Cuiling Shang; Huayu Wang; Chunpo Ge; Tianjun Ni; Kaiwen Chang
Journal:  Anal Bioanal Chem       Date:  2022-08-05       Impact factor: 4.478

Review 3.  Structural Elucidation, Modification, and Structure-Activity Relationship of Polysaccharides in Chinese Herbs: A Review.

Authors:  Bei Wang; Lingling Yan; Shuchen Guo; Ling Wen; Mengli Yu; Liang Feng; Xiaobin Jia
Journal:  Front Nutr       Date:  2022-05-20

Review 4.  Polysaccharide-based nanomedicines for cancer immunotherapy: A review.

Authors:  Yujun Zeng; Yufan Xiang; Ruilong Sheng; Helena Tomás; João Rodrigues; Zhongwei Gu; Hu Zhang; Qiyong Gong; Kui Luo
Journal:  Bioact Mater       Date:  2021-03-18

5.  Sarcodia suieae acetyl-xylogalactan regulate RAW 264.7 macrophage NF-kappa B activation and IL-1 beta cytokine production in macrophage polarization.

Authors:  Tsung-Meng Wu; Fan-Hua Nan; Kuan-Chu Chen; Yu-Sheng Wu
Journal:  Sci Rep       Date:  2019-12-23       Impact factor: 4.379

6.  A Nano Drug Delivery System Based on Angelica sinensis Polysaccharide for Combination of Chemotherapy and Immunotherapy.

Authors:  Min-Zhe Wang; Xin He; Zhe Yu; Hong Wu; Tie-Hong Yang
Journal:  Molecules       Date:  2020-07-07       Impact factor: 4.411

7.  Selenium-Containing Exopolysaccharides Isolated from the Culture Medium of Lentinula edodes: Structure and Biological Activity.

Authors:  Sandra Górska-Jakubowska; Marzenna Klimaszewska; Piotr Podsadni; Beata Kaleta; Radosław Zagożdżon; Sabina Górska; Andrzej Gamian; Tomasz Strączek; Czesław Kapusta; Marcin Cieślak; Julia Kaźmierczak-Barańska; Barbara Nawrot; Jadwiga Turło
Journal:  Int J Mol Sci       Date:  2021-12-02       Impact factor: 5.923

Review 8.  Polysaccharides as Potential Anti-tumor Biomacromolecules -A Review.

Authors:  Rui Guo; Min Chen; Yangyang Ding; Pengyao Yang; Mengjiao Wang; Haihui Zhang; Yuanqing He; Haile Ma
Journal:  Front Nutr       Date:  2022-02-28

9.  DoRWA3 from Dendrobium officinale Plays an Essential Role in Acetylation of Polysaccharides.

Authors:  Can Si; Jaime A Teixeira da Silva; Chunmei He; Zhenming Yu; Conghui Zhao; Haobin Wang; Mingze Zhang; Jun Duan
Journal:  Int J Mol Sci       Date:  2020-08-28       Impact factor: 5.923

Review 10.  Natural Polysaccharides and Their Derivates: A Promising Natural Adjuvant for Tumor Immunotherapy.

Authors:  Ye Li; Xiaomin Wang; Xiaoran Ma; Cun Liu; Jibiao Wu; Changgang Sun
Journal:  Front Pharmacol       Date:  2021-04-14       Impact factor: 5.810

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