Literature DB >> 29366941

Inorganic nanoparticles: A potential cancer therapy for human welfare.

Arivalagan Pugazhendhi1, Thomas Nesakumar Jebakumar Immanuel Edison2, Indira Karuppusamy3, Brindhadevi Kathirvel4.   

Abstract

Cancer is an abnormal condition leading to uncontrolled cell division which causes damage to the body tissues. Around 100 types of cancer are studied so far namely breast cancer, lung cancer, skin cancer, prostate cancer, colon cancer and lymphoma. Major cancer therapies include chemotherapy, surgery and radiations but their major drawbacks are non-specifically distributed antitumor agents, uneven delivery of drug concentration to the tumour and low monitoring. Nanoparticles (NPs) are the newly trending field of nanomedicine implied in cancer therapy. The structural characteristics of NPs makes them excellent mode for targeting and penetrating the abnormal cell growth caused by cancer. They can potentially enter the abnormal cells causing DNA damage and determine the defects in the genes. Apart from targeting cancer cells they also aid in drug delivery, imaging of abnormal cells, release and monitoring of therapeutic agents against cancer. The present review deals with the inorganic NPs mediated pharmacotherapy, potential strategies for developing drug delivery system, evaluate the merits and demerits of traditional chemotherapy and nanotherapy for significantly improving the treatment of cancers.
Copyright © 2018 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Cancer; Drug delivery; Nanomedicine; Nanoparticles; Nanotechnology

Mesh:

Substances:

Year:  2018        PMID: 29366941     DOI: 10.1016/j.ijpharm.2018.01.034

Source DB:  PubMed          Journal:  Int J Pharm        ISSN: 0378-5173            Impact factor:   5.875


  57 in total

1.  A reversible fluorescent probe for monitoring Ag(I) ions.

Authors:  Zelong Lim; David G Smith; Jacek L Kolanowski; Rebecca L Mattison; Jonathan C Knowles; Song-Yi Baek; Wojciech Chrzanowski; Elizabeth J New
Journal:  J R Soc Interface       Date:  2018-07       Impact factor: 4.118

2.  Enhancing malaria control using Lagenaria siceraria and its mediated zinc oxide nanoparticles against the vector Anopheles stephensi and its parasite Plasmodium falciparum.

Authors:  V N Kalpana; Khaloud Mohammed Alarjani; V Devi Rajeswari
Journal:  Sci Rep       Date:  2020-12-09       Impact factor: 4.379

3.  Chitosan And N, N, N-Trimethyl Chitosan Nanoparticle Encapsulation Of Ocimum Gratissimum Essential Oil: Optimised Synthesis, In Vitro Release And Bioactivity.

Authors:  Confidence Onyebuchi; Doğa Kavaz
Journal:  Int J Nanomedicine       Date:  2019-09-20

4.  Graphene-based hybrid nanoparticle of doxorubicin for cancer chemotherapy.

Authors:  Nagaraja SreeHarsha; Rahul Maheshwari; Bandar E Al-Dhubiab; Muktika Tekade; Mukesh Chandra Sharma; Katharigatta N Venugopala; Rakesh Kumar Tekade; Abdullah M Alzahrani
Journal:  Int J Nanomedicine       Date:  2019-09-12

5.  Comparative Assessment of Antioxidant, Anti-Diabetic and Cytotoxic Effects of Three Peel/Shell Food Waste Extract-Mediated Silver Nanoparticles.

Authors:  Gitishree Das; Han-Seung Shin; Jayanta Kumar Patra
Journal:  Int J Nanomedicine       Date:  2020-11-17

6.  Hepatic histopathological and ultrastructural alterations induced by 10 nm silver nanoparticles.

Authors:  Amin Al-Doaiss; Qais Jarrar; Said Moshawih
Journal:  IET Nanobiotechnol       Date:  2020-07       Impact factor: 1.847

7.  Facile synthesis of reduced graphene oxide using Acalypha indica and Raphanus sativus extracts and their in vitro cytotoxicity activity against human breast (MCF-7) and lung (A549) cancer cell lines.

Authors:  Parthipan Punniyakotti; Rajasekar Aruliah; Subramania Angaiah
Journal:  3 Biotech       Date:  2021-03-05       Impact factor: 2.406

8.  Characterization and Evaluation of Multiple Biological Activities of Silver Nanoparticles Fabricated from Dragon Tongue Bean Outer Peel Extract.

Authors:  Jayanta Kumar Patra; Han-Seung Shin; Gitishree Das
Journal:  Int J Nanomedicine       Date:  2021-02-11

9.  Antitumor activity via apoptotic cell death pathway of water soluble copper(II) complexes: effect of the diamino unit on selectivity against lung cancer NCI-H460 cell line.

Authors:  Wagner da S Terra; Érika S Bull; Samila R Morcelli; Rafaela R Moreira; Leide Laura F Maciel; João Carlos de A Almeida; Milton M Kanashiro; Christiane Fernandes; Adolfo Horn
Journal:  Biometals       Date:  2021-04-04       Impact factor: 2.949

10.  Magnetic Particles with Polymeric Shells Bearing Cholesterol Moieties Sensitize Breast Cancer Cells to Low Doses of Doxorubicin.

Authors:  Karolina H Markiewicz; Katarzyna Niemirowicz-Laskowska; Dawid Szymczuk; Kacper Makarewicz; Iwona Misztalewska-Turkowicz; Przemysław Wielgat; Anna M Majcher-Fitas; Sylwia Milewska; Halina Car; Agnieszka Z Wilczewska
Journal:  Int J Mol Sci       Date:  2021-05-05       Impact factor: 5.923

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