Literature DB >> 29351652

Early Results in Flow Diverter Sizing by Computational Simulation: Quantification of Size Change and Simulation Error Assessment.

Ana Paula Narata1, Jordi Blasco2, Luis San Roman2, Juan Miguel Macho2, Hector Fernandez3, Raquel Kale Moyano3, Renaud Winzenrieth3, Ignacio Larrabide3,4.   

Abstract

BACKGROUND: Sizing of flow diverters (FDs) stent in the treatment of intracranial aneurysms is a challenging task due to the change of stent length after implantation.
OBJECTIVE: To quantify the size change and assess the error in length prediction in 82 simulated FD deployments.
METHODS: Eighty-two consecutive patients treated with FDs were retrospectively analyzed. Implanted FD length was measured from angiographic images and compared to the nominal sizes of the implanted device. Length change was obtained by subtracting the nominal length from the real length and dividing by the nominal length. Implanted devices were simulated on 3-dimensional models of each patient. Simulation error was obtained by subtracting real length from simulated length and dividing by the real length of the FD. Subanalysis was done using ANOVA. Statistical significance was set to P < .05, and bootstrap resampling was used.
RESULTS: When assessing the length change of the FD after implantation, changes of 30% in average and up to 80% with reference to the nominal length of the device were observed. The simulation results showed a lower error of 3.52% in average with a maximum of 30%. Paired t-test showed nonsignificant differences between measured and real length (P = .07, with the mean of differences at 0.45 mm, 95% confidence interval [-0.950 0.038]).
CONCLUSION: Nominal length is not an accurate sizing metric when choosing the size of an FD irrespective of the brand and manufacturer. Good estimation of the final length of the stent after deployment as expressed by an error of 3.5% in average.

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Year:  2018        PMID: 29351652     DOI: 10.1093/ons/opx288

Source DB:  PubMed          Journal:  Oper Neurosurg (Hagerstown)        ISSN: 2332-4252            Impact factor:   2.703


  3 in total

1.  Comparison of Pipeline Embolization Device Sizing Based on Conventional 2D Measurements and Virtual Simulation Using the Sim&Size Software: An Agreement Study.

Authors:  J M Ospel; G Gascou; V Costalat; L Piergallini; K A Blackham; D W Zumofen
Journal:  AJNR Am J Neuroradiol       Date:  2019-02-07       Impact factor: 3.825

2.  Deployment of flow diverter devices: prediction of foreshortening and validation of the simulation in 18 clinical cases.

Authors:  Robert Kellermann; Steffen Serowy; Oliver Beuing; Martin Skalej
Journal:  Neuroradiology       Date:  2019-08-31       Impact factor: 2.804

3.  Cerebral Aneurysm Occlusion at 12-Month Follow-Up After Flow-Diverter Treatment: Statistical Modeling for V&V With Real-World Data.

Authors:  Ana Paula Narata; Laura Obradó; Raquel Kalé Moyano; Juan M Macho; Jordi Blasco; Antonio López Rueda; Luis San Roman; Sebastian Remollo; Claudia Marinelli; Rosana Cepeda; Héctor Fernández; Ignacio Larrabide
Journal:  Front Med Technol       Date:  2021-09-17
  3 in total

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