Emily Y Pan1, Dershan Luo2, Tinsu Pan3. 1. Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1352, Houston, TX, 70030-4009, USA. 2. Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas, 70030, USA. 3. Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, 1515 Holcombe Blvd., Unit 1352, Houston, TX, 70030-4009, USA. tpan@mdanderson.org.
Abstract
BACKGROUND: Average CT has been shown to be more accurate than conventional helical CT in quantitation of the PET data. The risk of CT irradiation of a cardiac implantable electronic device (CIED) causing an adverse event is low and is generally outweighed by the clinical benefit of a medically indicated examination. However, irradiation of CIED over one breath cycle in cine CT scan for average CT could impose risks on a patient who is pacing dependent. The purpose of this study was to demonstrate that low-dose average CT can be safe for CIED. METHODS: A Medtronic CIED of model Protecta VR was submerged in a saline bath for a series of 4-s cine CT scans on a GE CT scanner programmed to deliver a 2-cm-wide radiation at a dose rate of 0.9 to 41.2 mGy/s to the CIED. The number of over-sensings was recorded as the interference of radiation to the CIED. RESULTS: Dose rates ≥ 1.9 mGy/s caused over-sensing. The higher the dose rate, the more over-sensings there were. The lowest dose rate of 0.9 mGy/s did not cause any over-sensing. CONCLUSIONS: Low-dose average CT at 0.9 mGy/s can be safe for a CIED patient who is pacing dependent.
BACKGROUND: Average CT has been shown to be more accurate than conventional helical CT in quantitation of the PET data. The risk of CT irradiation of a cardiac implantable electronic device (CIED) causing an adverse event is low and is generally outweighed by the clinical benefit of a medically indicated examination. However, irradiation of CIED over one breath cycle in cine CT scan for average CT could impose risks on a patient who is pacing dependent. The purpose of this study was to demonstrate that low-dose average CT can be safe for CIED. METHODS: A Medtronic CIED of model Protecta VR was submerged in a saline bath for a series of 4-s cine CT scans on a GE CT scanner programmed to deliver a 2-cm-wide radiation at a dose rate of 0.9 to 41.2 mGy/s to the CIED. The number of over-sensings was recorded as the interference of radiation to the CIED. RESULTS: Dose rates ≥ 1.9 mGy/s caused over-sensing. The higher the dose rate, the more over-sensings there were. The lowest dose rate of 0.9 mGy/s did not cause any over-sensing. CONCLUSIONS: Low-dose average CT at 0.9 mGy/s can be safe for a CIEDpatient who is pacing dependent.
Entities:
Keywords:
PET/CT imaging; computed tomography (CT); myocardial perfusion imaging: PET
Authors: Tinsu Pan; Osama Mawlawi; Sadek A Nehmeh; Yusuf E Erdi; Dershan Luo; Hui H Liu; Richard Castillo; Radhe Mohan; Zhongxing Liao; H A Macapinlac Journal: J Nucl Med Date: 2005-09 Impact factor: 10.057
Authors: Tinsu Pan; Osama Mawlawi; Dershan Luo; Hui H Liu; Pai-Chun M Chi; Martha V Mar; Gregory Gladish; Mylene Truong; Jeremy Erasmus; Zhongxing Liao; H A Macapinlac Journal: Med Phys Date: 2006-10 Impact factor: 4.071