Literature DB >> 29338304

Investigation of the use of external aluminium targets for portal imaging in a medical accelerator using Geant4 Monte Carlo simulation.

Hyungdong Kim1, Byungyong Kim2, Jonggeun Baek3, Youngkee Oh4, Sangmo Yun1, Hyunsoo Jang3.   

Abstract

OBJECTIVE: To install a low-Z target on the wedge tray mount of a medical linear accelerator to create a new image beam and to confirm image contrast enhancement.
METHODS: Experimental low-energy photon beams were produced with the linac running in the 6 MeV electron mode and with a low-Z target installed on the wedge tray mount [denoted 6 MeV (low-Z target)]. Geant4 Monte Carlo simulation was performed to analyse the energy spectrum and image contrast of a 6 MeV (low-Z target) beam. This study modelled the 6 MeV (low-Z target) beam and the 6 MV (megavoltage) radiotherapy photon beam and verified model validity by measurement. In addition, a contrast phantom was modelled to quantitatively compare the image contrasts of the 6 MeV (low-Z target) beam and the 6 MV radiotherapy photon beam. A low-Z target was fabricated to generate low-energy photons (25-150 keV) from incident electrons, and a portal image of the Alderson RANDO phantom was acquired using a clinical linear accelerator for qualitative analysis.
RESULTS: The measured and calculated percentage depth dose of the 6 MV photon and 6 MeV (Al) beams were consistent within 1.5 and 1.6%, respectively, and calculated lateral profiles of the 6 MV photon beam and the 6 MeV (Al) beam were consistent with the measured results within 1.5 and 1.9%, respectively. Although low-energy photons (25-150 keV) of the 6 MV photon beam were only 0.3%, the Be, C, and Al low-Z targets, but not the Ti target, generated 34.4 to 38.5% low-energy photons. In 5 to 20 cm water phantoms, contrast of the 6 MeV (Al) beam was approximately 1.16 times greater than that of the 6 MV beam. The contrasts of 6 MeV (Al) and 6 MV photon beams in the 20 cm water phantom were ~34% lower than those in the 5 cm water phantom. 6 MeV (Al)/CR (computed radiography) images of the human body phantom were more vivid and detailed than 6 MV/EPID (electronic portal imaging device) and 6 MeV (Al)/EPID images.
CONCLUSION: The experimental beam with a low-Z target, which was simply installed on the wedge tray mount of the radiotherapy linear accelerator, generated significantly more low-energy photons than the 6 MV radiotherapy photon beam, and provided better quality portal images. Advances in knowledge: This study shows that, unlike the existing low-Z beam studies, a low-Z target can be installed outside the head of a linear accelerator to improve portal image quality.

Entities:  

Mesh:

Substances:

Year:  2018        PMID: 29338304      PMCID: PMC5965989          DOI: 10.1259/bjr.20170376

Source DB:  PubMed          Journal:  Br J Radiol        ISSN: 0007-1285            Impact factor:   3.039


  19 in total

1.  A low Z linac and flat panel imager: comparison with the conventional imaging approach.

Authors:  D A Roberts; V N Hansen; A C Niven; M G Thompson; J Seco; P M Evans
Journal:  Phys Med Biol       Date:  2008-10-20       Impact factor: 3.609

2.  A thin target approach for portal imaging in medical accelerators.

Authors:  A Tsechanski; A F Bielajew; S Faermann; Y Krutman
Journal:  Phys Med Biol       Date:  1998-08       Impact factor: 3.609

3.  X-ray quantum limited portal imaging using amorphous silicon flat-panel arrays.

Authors:  P Munro; D C Bouius
Journal:  Med Phys       Date:  1998-05       Impact factor: 4.071

4.  Beam generation and planar imaging at energies below 2.40 MeV with carbon and aluminum linear accelerator targets.

Authors:  David Parsons; James L Robar
Journal:  Med Phys       Date:  2012-07       Impact factor: 4.071

5.  A Monte Carlo approach to validation of FFF VMAT treatment plans for the TrueBeam linac.

Authors:  Ermias Gete; Cheryl Duzenli; Marie-Pierre Milette; Ante Mestrovic; Derek Hyde; Alanah Mary Bergman; Tony Teke
Journal:  Med Phys       Date:  2013-02       Impact factor: 4.071

6.  Generation and modelling of megavoltage photon beams for contrast-enhanced radiation therapy.

Authors:  J L Robar
Journal:  Phys Med Biol       Date:  2006-10-09       Impact factor: 3.609

7.  Daily cone-beam computed tomography used to determine tumour shrinkage and localisation in lung cancer patients.

Authors:  Marianne Marquard Knap; Lone Hoffmann; Marianne Nordsmark; Anne Vestergaard
Journal:  Acta Oncol       Date:  2010-10       Impact factor: 4.089

8.  Optimization of accelerator target and detector for portal imaging using Monte Carlo simulation and experiment.

Authors:  S Flampouri; P M Evans; F Verhaegen; A E Nahum; E Spezi; M Partridge
Journal:  Phys Med Biol       Date:  2002-09-21       Impact factor: 3.609

9.  Megavoltage imaging with low Z targets: implementation and characterization of an investigational system.

Authors:  O Z Ostapiak; P F O'Brien; B A Faddegon
Journal:  Med Phys       Date:  1998-10       Impact factor: 4.071

10.  Assessment of setup uncertainties for various tumor sites when using daily CBCT for more than 2200 VMAT treatments.

Authors:  Young-Kee Oh; Jong-Geun Baek; Ok-Bae Kim; Jin-Hee Kim
Journal:  J Appl Clin Med Phys       Date:  2014-03-06       Impact factor: 2.102

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.