Literature DB >> 22830788

Beam generation and planar imaging at energies below 2.40 MeV with carbon and aluminum linear accelerator targets.

David Parsons1, James L Robar.   

Abstract

PURPOSE: Recent work has demonstrated improvement of image quality with low-Z linear accelerator targets and energies as low as 3.5 MV. In this paper, the authors lower the incident electron beam energy between 1.90 and 2.35 MeV and assess the improvement of megavoltage planar image quality with the use of carbon and aluminum linear accelerator targets.
METHODS: The bending magnet shunt current was adjusted in a Varian linear accelerator to allow selection of mean electron energy between 1.90 and 2.35 MeV. Linac set points were altered to increase beam current to allow experimental imaging in a practical time frame. Electron energy was determined through comparison of measured and Monte Carlo modeled depth dose curves. Planar image CNR and spatial resolution measurements were performed to quantify the improvement of image quality. Magnitudes of improvement are explained with reference to Monte Carlo generated energy spectra.
RESULTS: After modifications to the linac, beam current was increased by a factor greater than four and incident electron energy was determined to have an adjustable range from 1.90 MeV to 2.35 MeV. CNR of cortical bone was increased by a factor ranging from 6.2 to 7.4 and 3.7 to 4.3 for thin and thick phantoms, respectively, compared to a 6 MV therapeutic beam for both aluminum and carbon targets. Spatial resolution was degraded slightly, with a relative change of 3% and 10% at 0.20 lp∕mm and 0.40 lp∕mm, respectively, when reducing energy from 2.35 to 1.90 MV. The percentage of diagnostic x-rays for the beams examined here, ranges from 46% to 54%.
CONCLUSION: It is possible to produce a large fraction of diagnostic energy x-rays by lowering the beam energy below 2.35 MV. By lowering the beam energy to 1.90 MV or 2.35 MV, CNR improves by factors ranging from 3.7 to 7.4 compared to a 6 MV therapy beam, with only a slight degradation of spatial resolution when lowering the energy from 2.35 MV to 1.90 MV.

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Year:  2012        PMID: 22830788     DOI: 10.1118/1.4730503

Source DB:  PubMed          Journal:  Med Phys        ISSN: 0094-2405            Impact factor:   4.071


  6 in total

1.  Low Z target switching to increase tumor endothelial cell dose enhancement during gold nanoparticle-aided radiation therapy.

Authors:  Ross I Berbeco; Alexandre Detappe; Panogiotis Tsiamas; David Parsons; Mammo Yewondwossen; James Robar
Journal:  Med Phys       Date:  2016-01       Impact factor: 4.071

2.  Electron modulated arc therapy (EMAT) using photon MLC for postmastectomy chest wall treatment I: Monte Carlo-based dosimetric characterizations.

Authors:  Chaoqiong Ma; David Parsons; Mingli Chen; Steve Jiang; Qing Hou; Xuejun Gu; Weiguo Lu
Journal:  Phys Med       Date:  2019-10-10       Impact factor: 2.685

3.  Investigation of the use of external aluminium targets for portal imaging in a medical accelerator using Geant4 Monte Carlo simulation.

Authors:  Hyungdong Kim; Byungyong Kim; Jonggeun Baek; Youngkee Oh; Sangmo Yun; Hyunsoo Jang
Journal:  Br J Radiol       Date:  2018-02-06       Impact factor: 3.039

4.  Investigation of planar image quality for a novel 2.5 MV diamond target beam from a radiotherapy linear accelerator.

Authors:  Jennifer M Borsavage; Amanda Cherpak; James L Robar
Journal:  Phys Imaging Radiat Oncol       Date:  2020-11-05

5.  Intermediate Megavoltage Photon Beams for Improved Lung Cancer Treatments.

Authors:  Ying Zhang; Yuanming Feng; Munir Ahmad; Xin Ming; Li Zhou; Jun Deng
Journal:  PLoS One       Date:  2015-12-16       Impact factor: 3.752

6.  Energy Modulated Photon Radiotherapy: A Monte Carlo Feasibility Study.

Authors:  Ying Zhang; Yuanming Feng; Xin Ming; Jun Deng
Journal:  Biomed Res Int       Date:  2016-02-09       Impact factor: 3.246

  6 in total

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