| Literature DB >> 29338119 |
Ji-Guang Wang1, Kazuomi Kario2, Chen-Huan Chen3, Jeong-Bae Park4, Satoshi Hoshide2, Yong Huo5, Hae-Young Lee6, Yan Li1, Masaki Mogi7, Masanori Munakata8, Sungha Park9, Dingliang Zhu1.
Abstract
Morning blood pressure (BP) surge is an important aspect of hypertension research. Morning BP monitoring could be a clinically relevant concept in the therapeutic management of hypertension and in the prevention of cardiovascular complications by defining and treating morning hypertension. Because antihypertensive medication is often taken in the morning, uncontrolled morning BP during the trough effect hours could be a hallmark of inadequate choice of antihypertensive regimen, such as the use of short- or intermediate-acting drugs, underdosing of drugs, or no use or underuse of combination therapy. To improve the management of hypertension in general and morning hypertension in particular, long-acting antihypertensive drugs should be used in appropriate, often full dosages and in proper combinations. The clinical usefulness of antihypertensive drugs with specific mechanisms for morning BP or split or timed dosing of long-acting drugs in controlling morning BP remains under investigation. ©2018 Wiley Periodicals, Inc.Entities:
Keywords: ambulatory blood pressure; antihypertensive treatment; home blood pressure; morning blood pressure; morning hypertension
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Year: 2018 PMID: 29338119 PMCID: PMC8030813 DOI: 10.1111/jch.13140
Source DB: PubMed Journal: J Clin Hypertens (Greenwich) ISSN: 1524-6175 Impact factor: 3.738