Literature DB >> 29335645

The new genetics of intelligence.

Robert Plomin1, Sophie von Stumm2.   

Abstract

Intelligence - the ability to learn, reason and solve problems - is at the forefront of behavioural genetic research. Intelligence is highly heritable and predicts important educational, occupational and health outcomes better than any other trait. Recent genome-wide association studies have successfully identified inherited genome sequence differences that account for 20% of the 50% heritability of intelligence. These findings open new avenues for research into the causes and consequences of intelligence using genome-wide polygenic scores that aggregate the effects of thousands of genetic variants.

Entities:  

Mesh:

Year:  2018        PMID: 29335645      PMCID: PMC5985927          DOI: 10.1038/nrg.2017.104

Source DB:  PubMed          Journal:  Nat Rev Genet        ISSN: 1471-0056            Impact factor:   53.242


  65 in total

1.  Multivariate genetic analyses of cognition and academic achievement from two population samples of 174,000 and 166,000 school children.

Authors:  Catherine M Calvin; Ian J Deary; Dinand Webbink; Pauline Smith; Cres Fernandes; Sang Hong Lee; Michelle Luciano; Peter M Visscher
Journal:  Behav Genet       Date:  2012-06-15       Impact factor: 2.805

Review 2.  Intelligence.

Authors:  Ian J Deary
Journal:  Annu Rev Psychol       Date:  2011-09-19       Impact factor: 24.137

Review 3.  Dissecting the genetics of complex traits using summary association statistics.

Authors:  Bogdan Pasaniuc; Alkes L Price
Journal:  Nat Rev Genet       Date:  2016-11-14       Impact factor: 53.242

Review 4.  Finding the missing heritability of complex diseases.

Authors:  Teri A Manolio; Francis S Collins; Nancy J Cox; David B Goldstein; Lucia A Hindorff; David J Hunter; Mark I McCarthy; Erin M Ramos; Lon R Cardon; Aravinda Chakravarti; Judy H Cho; Alan E Guttmacher; Augustine Kong; Leonid Kruglyak; Elaine Mardis; Charles N Rotimi; Montgomery Slatkin; David Valle; Alice S Whittemore; Michael Boehnke; Andrew G Clark; Evan E Eichler; Greg Gibson; Jonathan L Haines; Trudy F C Mackay; Steven A McCarroll; Peter M Visscher
Journal:  Nature       Date:  2009-10-08       Impact factor: 49.962

5.  Explaining the increasing heritability of cognitive ability across development: a meta-analysis of longitudinal twin and adoption studies.

Authors:  Daniel A Briley; Elliot M Tucker-Drob
Journal:  Psychol Sci       Date:  2013-07-01

6.  Stability and change in intelligence from age 11 to ages 70, 79, and 87: the Lothian Birth Cohorts of 1921 and 1936.

Authors:  Alan J Gow; Wendy Johnson; Alison Pattie; Caroline E Brett; Beverly Roberts; John M Starr; Ian J Deary
Journal:  Psychol Aging       Date:  2011-03

7.  Genetic contributions to stability and change in intelligence from childhood to old age.

Authors:  Ian J Deary; Jian Yang; Gail Davies; Sarah E Harris; Albert Tenesa; David Liewald; Michelle Luciano; Lorna M Lopez; Alan J Gow; Janie Corley; Paul Redmond; Helen C Fox; Suzanne J Rowe; Paul Haggarty; Geraldine McNeill; Michael E Goddard; David J Porteous; Lawrence J Whalley; John M Starr; Peter M Visscher
Journal:  Nature       Date:  2012-01-18       Impact factor: 49.962

8.  Multi-polygenic score approach to trait prediction.

Authors:  E Krapohl; H Patel; S Newhouse; C J Curtis; S von Stumm; P S Dale; D Zabaneh; G Breen; P F O'Reilly; R Plomin
Journal:  Mol Psychiatry       Date:  2017-08-08       Impact factor: 15.992

9.  Common genetic variants explain the majority of the correlation between height and intelligence: the generation Scotland study.

Authors:  Riccardo E Marioni; G David Batty; Caroline Hayward; Shona M Kerr; Archie Campbell; Lynne J Hocking; David J Porteous; Peter M Visscher; Ian J Deary
Journal:  Behav Genet       Date:  2014-02-20       Impact factor: 2.805

10.  Phenome-wide analysis of genome-wide polygenic scores.

Authors:  E Krapohl; J Euesden; D Zabaneh; J-B Pingault; K Rimfeld; S von Stumm; P S Dale; G Breen; P F O'Reilly; R Plomin
Journal:  Mol Psychiatry       Date:  2015-08-25       Impact factor: 15.992

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  69 in total

1.  A Polygenic Score for Higher Educational Attainment is Associated with Larger Brains.

Authors:  Maxwell L Elliott; Daniel W Belsky; Kevin Anderson; David L Corcoran; Tian Ge; Annchen Knodt; Joseph A Prinz; Karen Sugden; Benjamin Williams; David Ireland; Richie Poulton; Avshalom Caspi; Avram Holmes; Terrie Moffitt; Ahmad R Hariri
Journal:  Cereb Cortex       Date:  2019-07-22       Impact factor: 5.357

2.  The Dynamic Associations Between Cortical Thickness and General Intelligence are Genetically Mediated.

Authors:  J Eric Schmitt; Armin Raznahan; Liv S Clasen; Greg L Wallace; Joshua N Pritikin; Nancy Raitano Lee; Jay N Giedd; Michael C Neale
Journal:  Cereb Cortex       Date:  2019-12-17       Impact factor: 5.357

3.  The Shared Genetic Basis of Educational Attainment and Cerebral Cortical Morphology.

Authors:  Tian Ge; Chia-Yen Chen; Alysa E Doyle; Richard Vettermann; Lauri J Tuominen; Daphne J Holt; Mert R Sabuncu; Jordan W Smoller
Journal:  Cereb Cortex       Date:  2019-07-22       Impact factor: 5.357

4.  Accounting for the shared environment in cognitive abilities and academic achievement with measured socioecological contexts.

Authors:  Laura E Engelhardt; Jessica A Church; K Paige Harden; Elliot M Tucker-Drob
Journal:  Dev Sci       Date:  2018-08-16

5.  Genetics of nurture: A test of the hypothesis that parents' genetics predict their observed caregiving.

Authors:  Jasmin Wertz; Jay Belsky; Terrie E Moffitt; Daniel W Belsky; HonaLee Harrington; Reut Avinun; Richie Poulton; Sandhya Ramrakha; Avshalom Caspi
Journal:  Dev Psychol       Date:  2019-03-28

6.  A genome-wide association study-derived polygenic score for interleukin-1β is associated with hippocampal volume in two samples.

Authors:  Reut Avinun; Adam Nevo; Annchen R Knodt; Maxwell L Elliott; Ahmad R Hariri
Journal:  Hum Brain Mapp       Date:  2019-05-22       Impact factor: 5.038

7.  Genome-wide association meta-analysis in 269,867 individuals identifies new genetic and functional links to intelligence.

Authors:  Jeanne E Savage; Philip R Jansen; Sven Stringer; Kyoko Watanabe; Julien Bryois; Christiaan A de Leeuw; Mats Nagel; Swapnil Awasthi; Peter B Barr; Jonathan R I Coleman; Katrina L Grasby; Anke R Hammerschlag; Jakob A Kaminski; Robert Karlsson; Eva Krapohl; Max Lam; Marianne Nygaard; Chandra A Reynolds; Joey W Trampush; Hannah Young; Delilah Zabaneh; Sara Hägg; Narelle K Hansell; Ida K Karlsson; Sten Linnarsson; Grant W Montgomery; Ana B Muñoz-Manchado; Erin B Quinlan; Gunter Schumann; Nathan G Skene; Bradley T Webb; Tonya White; Dan E Arking; Dimitrios Avramopoulos; Robert M Bilder; Panos Bitsios; Katherine E Burdick; Tyrone D Cannon; Ornit Chiba-Falek; Andrea Christoforou; Elizabeth T Cirulli; Eliza Congdon; Aiden Corvin; Gail Davies; Ian J Deary; Pamela DeRosse; Dwight Dickinson; Srdjan Djurovic; Gary Donohoe; Emily Drabant Conley; Johan G Eriksson; Thomas Espeseth; Nelson A Freimer; Stella Giakoumaki; Ina Giegling; Michael Gill; David C Glahn; Ahmad R Hariri; Alex Hatzimanolis; Matthew C Keller; Emma Knowles; Deborah Koltai; Bettina Konte; Jari Lahti; Stephanie Le Hellard; Todd Lencz; David C Liewald; Edythe London; Astri J Lundervold; Anil K Malhotra; Ingrid Melle; Derek Morris; Anna C Need; William Ollier; Aarno Palotie; Antony Payton; Neil Pendleton; Russell A Poldrack; Katri Räikkönen; Ivar Reinvang; Panos Roussos; Dan Rujescu; Fred W Sabb; Matthew A Scult; Olav B Smeland; Nikolaos Smyrnis; John M Starr; Vidar M Steen; Nikos C Stefanis; Richard E Straub; Kjetil Sundet; Henning Tiemeier; Aristotle N Voineskos; Daniel R Weinberger; Elisabeth Widen; Jin Yu; Goncalo Abecasis; Ole A Andreassen; Gerome Breen; Lene Christiansen; Birgit Debrabant; Danielle M Dick; Andreas Heinz; Jens Hjerling-Leffler; M Arfan Ikram; Kenneth S Kendler; Nicholas G Martin; Sarah E Medland; Nancy L Pedersen; Robert Plomin; Tinca J C Polderman; Stephan Ripke; Sophie van der Sluis; Patrick F Sullivan; Scott I Vrieze; Margaret J Wright; Danielle Posthuma
Journal:  Nat Genet       Date:  2018-06-25       Impact factor: 38.330

Review 8.  Psychopathy.

Authors:  Stephane A De Brito; Adelle E Forth; Arielle R Baskin-Sommers; Inti A Brazil; Eva R Kimonis; Dustin Pardini; Paul J Frick; Robert James R Blair; Essi Viding
Journal:  Nat Rev Dis Primers       Date:  2021-07-08       Impact factor: 52.329

9.  Genomic prediction of cognitive traits in childhood and adolescence.

Authors:  A G Allegrini; S Selzam; K Rimfeld; S von Stumm; J B Pingault; R Plomin
Journal:  Mol Psychiatry       Date:  2019-04-11       Impact factor: 15.992

10.  Premorbid Adjustment and IQ in Patients With First-Episode Psychosis: A Multisite Case-Control Study of Their Relationship With Cannabis Use.

Authors:  Laura Ferraro; Caterina La Cascia; Diego Quattrone; Lucia Sideli; Domenica Matranga; Veronica Capuccio; Giada Tripoli; Charlotte Gayer-Anderson; Craig Morgan; Musa B Sami; Pak Sham; Lieuwe de Haan; Eva Velthorst; Hannah E Jongsma; James B Kirkbride; Bart P F Rutten; Alexander L Richards; Laura Roldan; Celso Arango; Miquel Bernardo; Julio Bobes; Julio Sanjuan; Jose Luis Santos; Manuel Arrojo; Ilaria Tarricone; Andrea Tortelli; Andrei Szöke; Cristina Marta Del-Ben; Jean-Paul Selten; Michael Lynskey; Peter B Jones; Jim Van Os; Daniele La Barbera; Robin M Murray; Marta Di Forti
Journal:  Schizophr Bull       Date:  2020-04-10       Impact factor: 9.306

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