Literature DB >> 293129

The frequency of private electrophoretic variants in Australian aborigines and indirect estimates of mutation rate.

K K Bhatia, N M Blake, R L Kirk.   

Abstract

The number of "private" electrophoretic variants of enzymes controlled by 25 loci has been used to obtain estimates of mutation rate in Australian Aborigines. Three different methods yield values of 6.11 X 10(-6), 2.78 X 10(-6), and 12.86 X 10(-6)/locus per generation for the total sample of Aborigines. One tribal population of Waljbiri in central Australia gives values of 2.99 X 10(-6) and 2.04 X 10(-6) for two of the methods, the third being unapplicable. The mean mutation rate for the total Aboriginal sample of 7.25 X 10(-6) is very similar to the value obtained by Neel and his colleagues for Amerindians in South America.

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Year:  1979        PMID: 293129      PMCID: PMC1686050     

Source DB:  PubMed          Journal:  Am J Hum Genet        ISSN: 0002-9297            Impact factor:   11.025


  11 in total

1.  Tribal and intertribal marriage among the Australian aborigines.

Authors:  N B TINDALE
Journal:  Hum Biol       Date:  1953-09       Impact factor: 0.553

2.  A genetic study of two French Guiana Amerindian populations. II. Rare electrophoretic variants.

Authors:  P Tchen; J Séger; E Bois; F Grenand; A Fribourg-Blanc; N Feingold
Journal:  Hum Genet       Date:  1978-12-29       Impact factor: 4.132

3.  Estimation of expected number of rare alleles of a locus and calculation of mutation rate.

Authors:  E D Rothman; J Adams
Journal:  Proc Natl Acad Sci U S A       Date:  1978-10       Impact factor: 11.205

4.  Founder effect and number of private polymorphisms observed in Amerindian tribes.

Authors:  J V Neel; E A Thompson
Journal:  Proc Natl Acad Sci U S A       Date:  1978-04       Impact factor: 11.205

5.  "Private" genetic variants and the frequency of mutation among South American Indians.

Authors:  J V Neel
Journal:  Proc Natl Acad Sci U S A       Date:  1973-12       Impact factor: 11.205

6.  Pattern of neutral polymorphism in a geographically structured population.

Authors:  M Kimura; T Maruyama
Journal:  Genet Res       Date:  1971-10       Impact factor: 1.588

7.  Indirect estimates of mutation rates in tribal Amerindians.

Authors:  J V Neel; E D Rothman
Journal:  Proc Natl Acad Sci U S A       Date:  1978-11       Impact factor: 11.205

8.  Estimation of mutation rate from rare protein variants.

Authors:  M Nei
Journal:  Am J Hum Genet       Date:  1977-05       Impact factor: 11.025

9.  Mutation rates from rare variants of proteins in Indian tribes.

Authors:  R Chakraborty; A K Roychoudhury
Journal:  Hum Genet       Date:  1978-08-31       Impact factor: 4.132

10.  Relationship between subunit size and number of rare electrophoretic alleles in human enzymes.

Authors:  W F Eanes; R K Koehn
Journal:  Biochem Genet       Date:  1978-10       Impact factor: 1.890

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  6 in total

1.  A revised indirect estimate of mutation rates in Amerindians.

Authors:  J V Neel; H W Mohrenweiser; E D Rothman; J M Naidu
Journal:  Am J Hum Genet       Date:  1986-05       Impact factor: 11.025

2.  Frequency of private electrophoretic variants and indirect estimates of mutation rate in Papua New Guinea.

Authors:  K K Bhatia; N M Blake; S W Serjeantson; R L Kirk
Journal:  Am J Hum Genet       Date:  1981-01       Impact factor: 11.025

3.  A "disproportion" between the frequency of rare electropmorphs and enzyme deficiency variants in Amerindians.

Authors:  H W Mohrenweiser; J V Neel
Journal:  Am J Hum Genet       Date:  1984-05       Impact factor: 11.025

4.  Is there a difference among human populations in the rate with which mutation produces electrophoretic variants?

Authors:  J V Neel; E Rothman
Journal:  Proc Natl Acad Sci U S A       Date:  1981-05       Impact factor: 11.205

5.  Search for mutations affecting protein structure in children of atomic bomb survivors: preliminary report.

Authors:  J V Neel; C Satoh; H B Hamilton; M Otake; K Goriki; T Kageoka; M Fujita; S Neriishi; J Asakawa
Journal:  Proc Natl Acad Sci U S A       Date:  1980-07       Impact factor: 11.205

6.  Expected number of rare alleles per locus in a sample and estimation of mutation rates.

Authors:  R Chakraborty
Journal:  Am J Hum Genet       Date:  1981-05       Impact factor: 11.025

  6 in total

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