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Literature DB >> 29304339

iPSC-Derived Organs In Vivo: Challenges and Promise.

Fabian Suchy¹, Tomoyuki Yamaguchi², Hiromitsu Nakauchi³.

Abstract

Transplanting iPSCs into the embryos of another species can generate functional organs for basic research and translational applications. We discuss forward-looking approaches and address key remaining challenges of generating iPSC-derived human organs in vivo.

Entities: Species

Mesh：

Year: 2018 PMID： 29304339 DOI： 10.1016/j.stem.2017.12.003

Source DB: PubMed Journal: Cell Stem Cell ISSN： 1875-9777 Impact factor: 24.633

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Cited

13 in total

Review 1. Innervation: the missing link for biofabricated tissues and organs.

Authors: Suradip Das; Wisberty J Gordián-Vélez; Harry C Ledebur; Foteini Mourkioti; Panteleimon Rompolas; H Isaac Chen; Mijail D Serruya; D Kacy Cullen
Journal: NPJ Regen Med Date: 2020-06-05

2. Mosaicism diminishes the value of pre-implantation embryo biopsies for detecting CRISPR/Cas9 induced mutations in sheep.

Authors: Marcela Vilarino; Fabian Patrik Suchy; Sheikh Tamir Rashid; Helen Lindsay; Juan Reyes; Bret Roberts McNabb; Talitha van der Meulen; Mark O Huising; Hiromitsu Nakauchi; Pablo Juan Ross
Journal: Transgenic Res Date: 2018-10-03 Impact factor: 2.788

Review 3. A critical look: Challenges in differentiating human pluripotent stem cells into desired cell types and organoids.

Authors: Jonas L Fowler; Lay Teng Ang; Kyle M Loh
Journal: Wiley Interdiscip Rev Dev Biol Date: 2019-11-19 Impact factor: 5.814

4. Kidney Regeneration in Later-Stage Mouse Embryos via Transplanted Renal Progenitor Cells.

Authors: Shuichiro Yamanaka; Yatsumu Saito; Toshinari Fujimoto; Tsuyoshi Takamura; Susumu Tajiri; Kei Matsumoto; Takashi Yokoo
Journal: J Am Soc Nephrol Date: 2019-09-23 Impact factor: 10.121

Review 5. Innervation: the missing link for biofabricated tissues and organs.

Authors: Suradip Das; Wisberty J Gordián-Vélez; Harry C Ledebur; Foteini Mourkioti; Panteleimon Rompolas; H Isaac Chen; Mijail D Serruya; D Kacy Cullen
Journal: NPJ Regen Med Date: 2020-06-05

6. Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs.

Authors: Mohammed F Shaheen; Dong Jin Joo; Jeffrey J Ross; Brett D Anderson; Harvey S Chen; Robert C Huebert; Yi Li; Bruce Amiot; Anne Young; Viviana Zlochiver; Erek Nelson; Taofic Mounajjed; Allan B Dietz; Gregory Michalak; Benjamin G Steiner; Dominique Seetapun Davidow; Christopher R Paradise; Andre J van Wijnen; Vijay H Shah; Mengfei Liu; Scott L Nyberg
Journal: Nat Biomed Eng Date: 2019-10-14 Impact factor: 25.671

iPSC-Derived Organs In Vivo: Challenges and Promise.

Review 1. Innervation: the missing link for biofabricated tissues and organs.

2. Mosaicism diminishes the value of pre-implantation embryo biopsies for detecting CRISPR/Cas9 induced mutations in sheep.

Review 3. A critical look: Challenges in differentiating human pluripotent stem cells into desired cell types and organoids.

4. Kidney Regeneration in Later-Stage Mouse Embryos via Transplanted Renal Progenitor Cells.

Review 5. Innervation: the missing link for biofabricated tissues and organs.

6. Sustained perfusion of revascularized bioengineered livers heterotopically transplanted into immunosuppressed pigs.

Review 7. Re-Endothelialization of Decellularized Liver Scaffolds: A Step for Bioengineered Liver Transplantation.

Review 8. Generating Human Organs via Interspecies Chimera Formation: Advances and Barriers.

Review 9. Diabetes Mellitus Is a Chronic Disease that Can Benefit from Therapy with Induced Pluripotent Stem Cells.

10. SOX2 for Stem Cell Therapy and Medical Use: Pros or Cons?