Literature DB >> 29296411

Spatial variations of multiple off-axial targets for a single isocenter SRS treatment in Novalis Tx linac system.

Sangroh Kim1, Tzu-Chi Tseng2, Andrew Morrow3.   

Abstract

PURPOSE: To develop a method to evaluate the positional variations of multiple off-axial targets for a single isocenter stereotactic radiosurgery (SRS) treatment in Novalis Tx linac system.Method and Materials: Five metallic ball bearing (BB) markers were placed sparsely in 3D off-axial locations (non-coplanar) inside a skull phantom as the representatives of multiple targets mimicking multiple brain metastases. The locations of the BB markers were carefully chosen to minimize overlapping of each other in a portal imaging detector plane. The skull phantom was immobilized by a frameless mask and CT scanned with a BrainLab Head&Neck Localizer using a GE Optima multi-detector CT (MDCT) scanner. The CT images were exported to iPlan treatment planning software and a multiple target PTV was drawn by combining all the contours of the BB markers. The margin of the MLC opening was selected as 3 mm expansion outward. Four non-coplanar arc beams were placed to generate a single isocenter SRS plan to treat the PTV. The skull phantom was localized to the treatment position using ExacTrac 6D Patient Positioning system. The four dynamic conformal arc beams were delivered using Novalis Tx system with portal imaging acquisition mode per 10% temporal resolution. The locations of the BB markers were visualized and analyzed with respect to the MLC aperture in the treatment plan similar to the Winston-Lutz (WL) test.
RESULTS: All the BB markers were clearly identified inside the MLC openings. The total positional errors for the MLC aperture were 0.61 ± 0.2 mm along the rotational path of the four arcs.
CONCLUSION: This study verified that the spatial deviations of multiple off-axial targets for a single isocenter SRS treatment plan is within sub-millimeter range in Novalis Tx linac system. Accompanied with the WL test, this simple test will quality-assure the spatial accuracies of the isocenter as well as the positions of multiple off-axial targets for the SRS treatment using a single isocenter multiple target treatment plan.

Entities:  

Keywords:  ExacTrac; Novalis Tx; SRS; Winston-Lutz; multiple brain metastases; non-coplanar; off-axis

Year:  2015        PMID: 29296411      PMCID: PMC5675496     

Source DB:  PubMed          Journal:  J Radiosurg SBRT


  31 in total

1.  A phantom study on the positioning accuracy of the Novalis Body system.

Authors:  Hui Yan; Fang-Fang Yin; Jae Ho Kim
Journal:  Med Phys       Date:  2003-12       Impact factor: 4.071

2.  Volumetric modulated arc therapy: IMRT in a single gantry arc.

Authors:  Karl Otto
Journal:  Med Phys       Date:  2008-01       Impact factor: 4.071

3.  2D/3D image fusion for accurate target localization and evaluation of a mask based stereotactic system in fractionated stereotactic radiotherapy of cranial lesions.

Authors:  Jian-Yue Jin; Samuel Ryu; Kathleen Faber; Tom Mikkelsen; Qing Chen; Shidong Li; Benjamin Movsas
Journal:  Med Phys       Date:  2006-12       Impact factor: 4.071

4.  Use of the BrainLAB ExacTrac X-Ray 6D system in image-guided radiotherapy.

Authors:  Jian-Yue Jin; Fang-Fang Yin; Stephen E Tenn; Paul M Medin; Timothy D Solberg
Journal:  Med Dosim       Date:  2008-04-01       Impact factor: 1.482

5.  Volumetric modulated arc therapy (VMAT) vs. serial tomotherapy, step-and-shoot IMRT and 3D-conformal RT for treatment of prostate cancer.

Authors:  Dirk Wolff; Florian Stieler; Grit Welzel; Friedlieb Lorenz; Yasser Abo-Madyan; Sabine Mai; Carsten Herskind; Martin Polednik; Volker Steil; Frederik Wenz; Frank Lohr
Journal:  Radiother Oncol       Date:  2009-09-16       Impact factor: 6.280

Review 6.  Whole brain radiotherapy for the treatment of multiple brain metastases.

Authors:  M N Tsao; N Lloyd; R Wong; E Chow; E Rakovitch; N Laperriere
Journal:  Cochrane Database Syst Rev       Date:  2006-07-19

7.  Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases.

Authors:  D Kondziolka; A Patel; L D Lunsford; A Kassam; J C Flickinger
Journal:  Int J Radiat Oncol Biol Phys       Date:  1999-09-01       Impact factor: 7.038

8.  Volumetric modulated arc therapy improves dosimetry and reduces treatment time compared to conventional intensity-modulated radiotherapy for locoregional radiotherapy of left-sided breast cancer and internal mammary nodes.

Authors:  Carmen C Popescu; Ivo A Olivotto; Wayne A Beckham; Will Ansbacher; Sergei Zavgorodni; Richard Shaffer; Elaine S Wai; Karl Otto
Journal:  Int J Radiat Oncol Biol Phys       Date:  2010-01-01       Impact factor: 7.038

9.  Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial.

Authors:  David W Andrews; Charles B Scott; Paul W Sperduto; Adam E Flanders; Laurie E Gaspar; Michael C Schell; Maria Werner-Wasik; William Demas; Janice Ryu; Jean-Paul Bahary; Luis Souhami; Marvin Rotman; Minesh P Mehta; Walter J Curran
Journal:  Lancet       Date:  2004-05-22       Impact factor: 79.321

Review 10.  Management of brain metastases.

Authors:  J B Posner
Journal:  Rev Neurol (Paris)       Date:  1992       Impact factor: 2.607

View more
  2 in total

Review 1.  Frameless Image-Guided Radiosurgery for Multiple Brain Metastasis Using VMAT: A Review and an Institutional Experience.

Authors:  Samir Abdallah Hanna; Anselmo Mancini; Alisson Henrique Dal Col; Rie Nadia Asso; Wellington Furtado Pimenta Neves-Junior
Journal:  Front Oncol       Date:  2019-08-07       Impact factor: 6.244

2.  Single-Isocenter Volumetric Modulated Arc Therapy (VMAT) Radiosurgery for Multiple Brain Metastases: Potential Loss of Target(s) Coverage Due to Isocenter Misalignment.

Authors:  Allison N Palmiero; Lana Critchfield; William St Clair; Marcus Randall; Damodar Pokhrel
Journal:  Cureus       Date:  2020-10-30
  2 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.