| Literature DB >> 29257126 |
Lindsay M Alexander1, Jasmine Escalera1, Lei Ai1, Charissa Andreotti1, Karina Febre1, Alexander Mangone1, Natan Vega-Potler1, Nicolas Langer1,2, Alexis Alexander1, Meagan Kovacs1, Shannon Litke1, Bridget O'Hagan1, Jennifer Andersen1, Batya Bronstein1, Anastasia Bui1, Marijayne Bushey1, Henry Butler1, Victoria Castagna1, Nicolas Camacho1, Elisha Chan1, Danielle Citera1, Jon Clucas1, Samantha Cohen3, Sarah Dufek4, Megan Eaves1, Brian Fradera1, Judith Gardner5, Natalie Grant-Villegas1, Gabriella Green1, Camille Gregory1, Emily Hart1, Shana Harris1, Megan Horton6, Danielle Kahn1, Katherine Kabotyanski1, Bernard Karmel5, Simon P Kelly7, Kayla Kleinman1, Bonhwang Koo1, Eliza Kramer1, Elizabeth Lennon5, Catherine Lord4, Ginny Mantello8, Amy Margolis9, Kathleen R Merikangas10, Judith Milham11, Giuseppe Minniti1, Rebecca Neuhaus1, Alexandra Levine1, Yael Osman1, Lucas C Parra3, Ken R Pugh12, Amy Racanello1, Anita Restrepo1, Tian Saltzman1, Batya Septimus1, Russell Tobe1,13, Rachel Waltz1, Anna Williams1, Anna Yeo1, Francisco X Castellanos14,15, Arno Klein1, Tomas Paus1,16,17, Bennett L Leventhal1,18, R Cameron Craddock1,13, Harold S Koplewicz1, Michael P Milham1,13.
Abstract
Technological and methodological innovations are equipping researchers with unprecedented capabilities for detecting and characterizing pathologic processes in the developing human brain. As a result, ambitions to achieve clinically useful tools to assist in the diagnosis and management of mental health and learning disorders are gaining momentum. To this end, it is critical to accrue large-scale multimodal datasets that capture a broad range of commonly encountered clinical psychopathology. The Child Mind Institute has launched the Healthy Brain Network (HBN), an ongoing initiative focused on creating and sharing a biobank of data from 10,000 New York area participants (ages 5-21). The HBN Biobank houses data about psychiatric, behavioral, cognitive, and lifestyle phenotypes, as well as multimodal brain imaging (resting and naturalistic viewing fMRI, diffusion MRI, morphometric MRI), electroencephalography, eye-tracking, voice and video recordings, genetics and actigraphy. Here, we present the rationale, design and implementation of HBN protocols. We describe the first data release (n=664) and the potential of the biobank to advance related areas (e.g., biophysical modeling, voice analysis).Entities:
Mesh：
Year: 2017 PMID： 29257126 PMCID： PMC5735921 DOI： 10.1038/sdata.2017.181
Source DB: PubMed Journal: Sci Data ISSN： 2052-4463 Impact factor: 6.444