Literature DB >> 29238095

Increased psychological distress among individuals with spinal cord injury is associated with central neuropathic pain rather than the injury characteristics.

Hila Gruener1, Gabi Zeilig2,3, Yocheved Laufer4, Nava Blumen2,3, Ruth Defrin5.   

Abstract

STUDY
DESIGN: Cross-sectional study.
OBJECTIVES: Central neuropathic pain (CNP) is common after spinal cord injury (SCI). The psychological impact of CNP is not clear. Previous studies reported depression and pain catastrophizing among patients with SCI and CNP; however, the lack of control groups prevented discerning whether these were attributed to CNP or to the SCI itself. The aim was to examine the psychological distress among individuals with SCI with and without CNP and controls to evaluate its impact and possible source.
SETTING: Outpatient clinic of a large rehabilitation center.
METHODS: Individuals with SCI and CNP (n = 27) and without CNP (n = 23), and able-bodied controls (n = 20) participated. Data collection included sociodemographics, SCI characteristics, and level of post-traumatic stress disorder (PTSD), anxiety, stress, depression, and pain catastrophizing. The sensory, affective, and cognitive dimensions of CNP were analyzed.
RESULTS: Individuals with SCI and CNP exhibited elevated levels of PTSD, anxiety, stress, depression, and pain catastrophizing compared to the two control groups, which presented similar levels. The psychological variables among the CNP group correlated positively only with the affective dimension of CNP. Neither CNP nor the psychological variables correlated with SCI characteristics.
CONCLUSIONS: Irrespective of CNP intensity, the affective dimension (suffering) is associated with increased psychological distress. Perhaps individual differences in the response to SCI and/or individual traits rather than the mere exposure to SCI may have a role in the emergence of CNP and psychological distress/mood dysfunction. Rehabilitation programs should prioritize stress management and prevention among individuals with SCI and CNP.

Entities:  

Mesh:

Year:  2017        PMID: 29238095     DOI: 10.1038/s41393-017-0014-6

Source DB:  PubMed          Journal:  Spinal Cord        ISSN: 1362-4393            Impact factor:   2.772


  60 in total

Review 1.  The cortical representation of pain.

Authors:  R D Treede; D R Kenshalo; R H Gracely; A K Jones
Journal:  Pain       Date:  1999-02       Impact factor: 6.961

2.  A global measure of perceived stress.

Authors:  S Cohen; T Kamarck; R Mermelstein
Journal:  J Health Soc Behav       Date:  1983-12

3.  Dimensions of catastrophic thinking associated with pain experience and disability in patients with neuropathic pain conditions.

Authors:  Michael J L Sullivan; Mary E Lynch; A J Clark
Journal:  Pain       Date:  2005-02       Impact factor: 6.961

4.  Mutual influence of posttraumatic stress disorder symptoms and chronic pain among injured accident survivors: a longitudinal study.

Authors:  J Jenewein; L Wittmann; H Moergeli; J Creutzig; U Schnyder
Journal:  J Trauma Stress       Date:  2009-12

Review 5.  Pain in patients with spinal cord injury.

Authors:  Nanna Brix Finnerup
Journal:  Pain       Date:  2012-12-22       Impact factor: 6.961

6.  Psychosocial factors and adjustment to chronic pain in spinal cord injury: replication and cross-validation.

Authors:  Ivan R Molton; Brenda L Stoelb; Mark P Jensen; Dawn M Ehde; Katherine A Raichle; Diana D Cardenas
Journal:  J Rehabil Res Dev       Date:  2009

7.  Pain and post-traumatic stress disorder symptoms during inpatient rehabilitation among operation enduring freedom/operation iraqi freedom veterans with spinal cord injury.

Authors:  Philip M Ullrich; Bridget M Smith; Linda Poggensee; Charlesnika T Evans; Kevin T Stroupe; Frances M Weaver; Stephen P Burns
Journal:  Arch Phys Med Rehabil       Date:  2012-08-01       Impact factor: 3.966

8.  Predicting the Risk for Central Pain Using the Sensory Components of the International Standards for Neurological Classification of Spinal Cord Injury.

Authors:  Yuval Levitan; Gabi Zeilig; Moshe Bondi; Erez Ringler; Ruth Defrin
Journal:  J Neurotrauma       Date:  2015-08-05       Impact factor: 5.269

9.  Pain among veterans with spinal cord injury.

Authors:  Philip M Ullrich; Mark P Jensen; John D Loeser; Diana D Cardenas; Frances M Weaver
Journal:  J Rehabil Res Dev       Date:  2008

Review 10.  Management of neuropathic pain following spinal cord injury: now and in the future.

Authors:  P J Siddall
Journal:  Spinal Cord       Date:  2008-11-11       Impact factor: 2.772

View more
  7 in total

1.  Post-traumatic stress disorder symptoms and pain intensity in persons with spinal cord injury.

Authors:  Heleen Kuiper; Christel C M van Leeuwen; David J Kopsky; Janneke M Stolwijk-Swüste; Marcel W M Post
Journal:  Spinal Cord       Date:  2021-01-25       Impact factor: 2.772

2.  Correlation between thyroid function, testosterone levels, and depressive symptoms in females with spinal cord injury.

Authors:  Benjamin Dirlikov; Sarah Lavoie; Kazuko Shem
Journal:  Spinal Cord Ser Cases       Date:  2019-06-27

Review 3.  Metformin: A Prospective Alternative for the Treatment of Chronic Pain.

Authors:  Guadalupe Del Carmen Baeza-Flores; Crystell Guadalupe Guzmán-Priego; Leonor Ivonne Parra-Flores; Janet Murbartián; Jorge Elías Torres-López; Vinicio Granados-Soto
Journal:  Front Pharmacol       Date:  2020-09-23       Impact factor: 5.810

4.  Association of psychological variants with functional outcomes among people with spinal cord injury.

Authors:  Mohammed Qasheesh; Mohammad Abu Shaphe; Amir Iqbal; Ahmad H Alghadir
Journal:  Sci Rep       Date:  2021-10-13       Impact factor: 4.379

Review 5.  Non-opioid pharmacologic treatment of chronic spinal cord injury-related pain.

Authors:  Mendel Kupfer; Christopher S Formal
Journal:  J Spinal Cord Med       Date:  2020-03-17       Impact factor: 1.985

6.  miR-30b Promotes spinal cord sensory function recovery via the Sema3A/NRP-1/PlexinA1/RhoA/ROCK Pathway.

Authors:  Xin Wang; Bo Li; Zhijie Wang; Fengyan Wang; Jing Liang; Chuanjie Chen; Lei Zhao; Bo Zhou; Xiaoling Guo; Liqun Ren; Xin Yuan; Xueming Chen; Tianyi Wang
Journal:  J Cell Mol Med       Date:  2020-09-25       Impact factor: 5.310

Review 7.  Central Neuropathic Mechanisms in Pain Signaling Pathways: Current Evidence and Recommendations.

Authors:  Omar Viswanath; Ivan Urits; James Burns; Karina Charipova; Kyle Gress; Alexandra McNally; Richard D Urman; Ali Welschmeyer; Amnon A Berger; Hisham Kassem; Manuel G Sanchez; Alan D Kaye; Treniece N Eubanks; Elyse M Cornett; Anh L Ngo
Journal:  Adv Ther       Date:  2020-04-10       Impact factor: 3.845

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.