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Literature DB >> 29196360

The use of panel testing in familial breast and ovarian cancer.

Matina Prapa¹, Joyce Solomons², Marc Tischkowitz^1,3.

Abstract

Advances in sequencing technology have led to the introduction of panel testing in hereditary breast and ovarian cancer. While direct-to-consumer testing services have become widely available, the clinical validity of many of the genes on panel tests remains contentious and risk management guidelines are often lacking. This article gives an overview of advantages with panel testing as well as important challenges, including clinical translation of test results. © Royal College of Physicians 2017. All rights reserved.

Entities: Disease

Keywords: breast cancer; gene panel; genetic testing and hereditary cancer; ovarian cancer

Mesh：

Substances：

Year: 2017 PMID： 29196360 PMCID： PMC6297688 DOI： 10.7861/clinmedicine.17-6-568

Source DB: PubMed Journal: Clin Med (Lond) ISSN： 1470-2118 Impact factor: 2.659

21 in total

1. Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing.

Authors: Tom Walsh; Silvia Casadei; Ming K Lee; Christopher C Pennil; Alex S Nord; Anne M Thornton; Wendy Roeb; Kathy J Agnew; Sunday M Stray; Anneka Wickramanayake; Barbara Norquist; Kathryn P Pennington; Rochelle L Garcia; Mary-Claire King; Elizabeth M Swisher
Journal: Proc Natl Acad Sci U S A Date: 2011-10-17 Impact factor: 11.205

2. Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel.

Authors: Nadine Tung; Chiara Battelli; Brian Allen; Rajesh Kaldate; Satish Bhatnagar; Karla Bowles; Kirsten Timms; Judy E Garber; Christina Herold; Leif Ellisen; Jill Krejdovsky; Kim DeLeonardis; Kristin Sedgwick; Kathleen Soltis; Benjamin Roa; Richard J Wenstrup; Anne-Renee Hartman
Journal: Cancer Date: 2014-09-03 Impact factor: 6.860

3. Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer.

Authors: Fergus J Couch; Steven N Hart; Priyanka Sharma; Amanda Ewart Toland; Xianshu Wang; Penelope Miron; Janet E Olson; Andrew K Godwin; V Shane Pankratz; Curtis Olswold; Seth Slettedahl; Emily Hallberg; Lucia Guidugli; Jaime I Davila; Matthias W Beckmann; Wolfgang Janni; Brigitte Rack; Arif B Ekici; Dennis J Slamon; Irene Konstantopoulou; Florentia Fostira; Athanassios Vratimos; George Fountzilas; Liisa M Pelttari; William J Tapper; Lorraine Durcan; Simon S Cross; Robert Pilarski; Charles L Shapiro; Jennifer Klemp; Song Yao; Judy Garber; Angela Cox; Hiltrud Brauch; Christine Ambrosone; Heli Nevanlinna; Drakoulis Yannoukakos; Susan L Slager; Celine M Vachon; Diana M Eccles; Peter A Fasching
Journal: J Clin Oncol Date: 2014-12-01 Impact factor: 44.544

4. Next-generation sequencing for the diagnosis of hereditary breast and ovarian cancer using genomic capture targeting multiple candidate genes.

Authors: Laurent Castéra; Sophie Krieger; Antoine Rousselin; Angélina Legros; Jean-Jacques Baumann; Olivia Bruet; Baptiste Brault; Robin Fouillet; Nicolas Goardon; Olivier Letac; Stéphanie Baert-Desurmont; Julie Tinat; Odile Bera; Catherine Dugast; Pascaline Berthet; Florence Polycarpe; Valérie Layet; Agnes Hardouin; Thierry Frébourg; Dominique Vaur
Journal: Eur J Hum Genet Date: 2014-02-19 Impact factor: 4.246

5. Clinical evaluation of a multiple-gene sequencing panel for hereditary cancer risk assessment.

Authors: Allison W Kurian; Emily E Hare; Meredith A Mills; Kerry E Kingham; Lisa McPherson; Alice S Whittemore; Valerie McGuire; Uri Ladabaum; Yuya Kobayashi; Stephen E Lincoln; Michele Cargill; James M Ford
Journal: J Clin Oncol Date: 2014-04-14 Impact factor: 44.544

Review 6. Hereditary ovarian and breast cancer: what have we learned?

Authors: H T Lynch; C Snyder; M J Casey
Journal: Ann Oncol Date: 2013-11 Impact factor: 32.976

Review 7. Hereditary breast and ovarian cancer due to mutations in BRCA1 and BRCA2.

Authors: Nancie Petrucelli; Mary B Daly; Gerald L Feldman
Journal: Genet Med Date: 2010-05 Impact factor: 8.822

8. Truncating mutations in the Fanconi anemia J gene BRIP1 are low-penetrance breast cancer susceptibility alleles.

Authors: Sheila Seal; Deborah Thompson; Anthony Renwick; Anna Elliott; Patrick Kelly; Rita Barfoot; Tasnim Chagtai; Hiran Jayatilake; Munaza Ahmed; Katarina Spanova; Bernard North; Lesley McGuffog; D Gareth Evans; Diana Eccles; Douglas F Easton; Michael R Stratton; Nazneen Rahman
Journal: Nat Genet Date: 2006-10-08 Impact factor: 38.330

9. Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients.

Authors: Holly LaDuca; A J Stuenkel; Jill S Dolinsky; Steven Keiles; Stephany Tandy; Tina Pesaran; Elaine Chen; Chia-Ling Gau; Erika Palmaer; Kamelia Shoaepour; Divya Shah; Virginia Speare; Stephanie Gandomi; Elizabeth Chao
Journal: Genet Med Date: 2014-04-24 Impact factor: 8.822