Literature DB >> 291902

Structure of the human G gamma-A gamma-delta-beta-globin gene locus.

R Bernards, P F Little, G Annison, R Williamson, R A Flavell.   

Abstract

We have constructed a physical map of the human G gamma-, A gamma-, delta-, and beta-globin genes. The previously described maps of the fetal and adult beta-like globin genes have been linked to one another by identification of a DNA fragment, generated by BamHI, that contains part of each of the A gamma- and delta-globin genes. The map obtained, which spans more than 40 kilobases, shows the following intergene distances: between G gamma and A gamma, 3500 base pairs; between A gamma and delta, 13,500 base pairs; and between delta and beta, 5500 base pairs. All genes are transcribed from the same DNA strand.

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Year:  1979        PMID: 291902      PMCID: PMC413030          DOI: 10.1073/pnas.76.10.4827

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  7 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

Review 2.  Haemoglobin synthesis during human fetal development.

Authors:  W G Wood
Journal:  Br Med Bull       Date:  1976-09       Impact factor: 4.291

3.  Analysis of the beta-delta-globin gene loci in normal and Hb Lepore DNA: direct determination of gene linkage and intergene distance.

Authors:  R A Flavell; J M Kooter; E De Boer; P F Little; R Williamson
Journal:  Cell       Date:  1978-09       Impact factor: 41.582

4.  Structure of the human fetal globin gene locus.

Authors:  P F Little; R A Flavell; J M Kooter; G Annison; R Williamson
Journal:  Nature       Date:  1979-03-15       Impact factor: 49.962

5.  The rabbit beta-globin gene contains a large large insert in the coding sequence.

Authors:  A J Jeffreys; R A Flavell
Journal:  Cell       Date:  1977-12       Impact factor: 41.582

6.  Isolation and partial sequence of recombinant plasmids containing human alpha-, beta- and gamma-globin cDNA fragments.

Authors:  P Little; P Curtis; C Coutelle; J Van den Berg; R Dalgleish; S Malcolm; M Courtney; D Westaway; R Williamson
Journal:  Nature       Date:  1978-06-22       Impact factor: 49.962

7.  Characterisation of deletions which affect the expression of fetal globin genes in man.

Authors:  E F Fritsch; R M Lawn; T Maniatis
Journal:  Nature       Date:  1979-06-14       Impact factor: 49.962

  7 in total
  10 in total

Review 1.  The myosin alkali light chain proteins and their genes.

Authors:  P J Barton; M E Buckingham
Journal:  Biochem J       Date:  1985-10-15       Impact factor: 3.857

2.  A novel rearrangement of the human beta-like globin gene cluster.

Authors:  R J Trent; D K Bowden; J M Old; J S Wainscoat; J B Clegg; D J Weatherall
Journal:  Nucleic Acids Res       Date:  1981-12-21       Impact factor: 16.971

3.  Cloning and direct examination of a structurally abnormal human beta 0-thalassemia globin gene.

Authors:  S H Orkin; R Kolodner; A Michelson; R Husson
Journal:  Proc Natl Acad Sci U S A       Date:  1980-06       Impact factor: 11.205

4.  The 5' flanking region of human epsilon-globin gene.

Authors:  F E Baralle; C C Shoulders; S Goodbourn; A Jeffreys; N J Proudfoot
Journal:  Nucleic Acids Res       Date:  1980-10-10       Impact factor: 16.971

5.  Algorithms for restriction map comparisons.

Authors:  M S Waterman; T F Smith; H L Katcher
Journal:  Nucleic Acids Res       Date:  1984-01-11       Impact factor: 16.971

Review 6.  The precursor to animal cell messenger RNA.

Authors:  C Coutelle
Journal:  Biochem J       Date:  1981-07-01       Impact factor: 3.857

7.  Mapping sequences in loops of nuclear DNA by their progressive detachment from the nuclear cage.

Authors:  P R Cook; I A Brazell
Journal:  Nucleic Acids Res       Date:  1980-07-11       Impact factor: 16.971

8.  Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells.

Authors:  D DiMaio; R Treisman; T Maniatis
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205

9.  Lines of BPV-transformed murine cells that constitutively express influenza virus hemagglutinin.

Authors:  J Sambrook; L Rodgers; J White; M J Gething
Journal:  EMBO J       Date:  1985-01       Impact factor: 11.598

10.  SV40 T antigen and the exocytotic pathway.

Authors:  S Sharma; L Rodgers; J Brandsma; M J Gething; J Sambrook
Journal:  EMBO J       Date:  1985-06       Impact factor: 11.598

  10 in total

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