Literature DB >> 29186216

Investigating d-lysine stereochemistry for epigenetic methylation, demethylation and recognition.

Roman Belle1, Abbas H K Al Temimi, Kiran Kumar, Bas J G E Pieters, Anthony Tumber, James E Dunford, Catrine Johansson, Udo Oppermann, Tom Brown, Christopher J Schofield, Richard J Hopkinson, Robert S Paton, Akane Kawamura, Jasmin Mecinović.   

Abstract

Histone lysine methylation is regulated by Nε-methyltransferases, demethylases, and Nε-methyl lysine binding proteins. Thermodynamic, catalytic and computational studies were carried out to investigate the interaction of three epigenetic protein classes with synthetic histone substrates containing l- and d-lysine residues. The results reveal that out of the three classes, Nε-methyl lysine binding proteins are superior in accepting lysines with the d-configuration.

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Year:  2017        PMID： 29186216      PMCID： PMC6345366          DOI： 10.1039/c7cc08028j

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  18 in total

Review 1.  Molecular mechanisms and potential functions of histone demethylases.

Authors:  Susanne Marije Kooistra; Kristian Helin
Journal:  Nat Rev Mol Cell Biol       Date:  2012-04-04       Impact factor: 94.444

Review 2.  SET domain protein lysine methyltransferases: Structure, specificity and catalysis.

Authors:  C Qian; M-M Zhou
Journal:  Cell Mol Life Sci       Date:  2006-12       Impact factor: 9.261

Review 3.  How chromatin-binding modules interpret histone modifications: lessons from professional pocket pickers.

Authors:  Sean D Taverna; Haitao Li; Alexander J Ruthenburg; C David Allis; Dinshaw J Patel
Journal:  Nat Struct Mol Biol       Date:  2007-11-05       Impact factor: 15.369

4.  Monitoring the activity of 2-oxoglutarate dependent histone demethylases by NMR spectroscopy: direct observation of formaldehyde.

Authors:  Richard J Hopkinson; Refaat B Hamed; Nathan R Rose; Timothy D W Claridge; Christopher J Schofield
Journal:  Chembiochem       Date:  2010-03-01       Impact factor: 3.164

5.  Lysine succinylation and lysine malonylation in histones.

Authors:  Zhongyu Xie; Junbiao Dai; Lunzhi Dai; Minjia Tan; Zhongyi Cheng; Yeming Wu; Jef D Boeke; Yingming Zhao
Journal:  Mol Cell Proteomics       Date:  2012-03-04       Impact factor: 5.911

Review 6.  D-amino acid in elderly tissues.

Authors:  Noriko Fujii
Journal:  Biol Pharm Bull       Date:  2005-09       Impact factor: 2.233

7.  Identification of 67 histone marks and histone lysine crotonylation as a new type of histone modification.

Authors:  Minjia Tan; Hao Luo; Sangkyu Lee; Fulai Jin; Jeong Soo Yang; Emilie Montellier; Thierry Buchou; Zhongyi Cheng; Sophie Rousseaux; Nisha Rajagopal; Zhike Lu; Zhen Ye; Qin Zhu; Joanna Wysocka; Yang Ye; Saadi Khochbin; Bing Ren; Yingming Zhao
Journal:  Cell       Date:  2011-09-16       Impact factor: 41.582

Review 8.  Mechanisms of human histone and nucleic acid demethylases.

Authors:  Louise J Walport; Richard J Hopkinson; Christopher J Schofield
Journal:  Curr Opin Chem Biol       Date:  2012-10-10       Impact factor: 8.822

9.  Recognition of trimethyllysine by a chromodomain is not driven by the hydrophobic effect.

Authors:  Robert M Hughes; Kimberly R Wiggins; Sepideh Khorasanizadeh; Marcey L Waters
Journal:  Proc Natl Acad Sci U S A       Date:  2007-06-20       Impact factor: 11.205

10.  Structural Chemistry of Human SET Domain Protein Methyltransferases.

Authors:  Matthieu Schapira
Journal:  Curr Chem Genomics       Date:  2011-08-22
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  8 in total

1.  Reading and erasing of the phosphonium analogue of trimethyllysine by epigenetic proteins.

Authors:  Roman Belle; Jos J A G Kamps; Jordi Poater; Kiran Kumar; Bas J G E Pieters; Eidarus Salah; Timothy D W Claridge; Robert S Paton; F Matthias Bickelhaupt; Akane Kawamura; Christopher J Schofield; Jasmin Mecinović
Journal:  Commun Chem       Date:  2022-03-07

2.  Comparison of Molecular Recognition of Trimethyllysine and Trimethylthialysine by Epigenetic Reader Proteins.

Authors:  Jordi C J Hintzen; Jordi Poater; Kiran Kumar; Abbas H K Al Temimi; Bas J G E Pieters; Robert S Paton; F Matthias Bickelhaupt; Jasmin Mecinović
Journal:  Molecules       Date:  2020-04-21       Impact factor: 4.411

3.  Lysine Ethylation by Histone Lysine Methyltransferases.

Authors:  Abbas H K Al Temimi; Michael Martin; Qingxi Meng; Danny C Lenstra; Ping Qian; Hong Guo; Elmar Weinhold; Jasmin Mecinović
Journal:  Chembiochem       Date:  2019-10-24       Impact factor: 3.164

4.  Fine-tuning of lysine side chain modulates the activity of histone lysine methyltransferases.

Authors:  Abbas H K Al Temimi; Jona Merx; Christian J van Noortwijk; Giordano Proietti; Romano Buijs; Paul B White; Floris P J T Rutjes; Thomas J Boltje; Jasmin Mecinović
Journal:  Sci Rep       Date:  2020-12-09       Impact factor: 4.379

Review 5.  Trimethyllysine: From Carnitine Biosynthesis to Epigenetics.

Authors:  Marijn N Maas; Jordi C J Hintzen; Miriam R B Porzberg; Jasmin Mecinović
Journal:  Int J Mol Sci       Date:  2020-12-11       Impact factor: 5.923

6.  Racemization in Post-Translational Modifications Relevance to Protein Aging, Aggregation and Neurodegeneration: Tip of the Iceberg.

Authors:  Victor V Dyakin; Thomas M Wisniewski; Abel Lajtha
Journal:  Symmetry (Basel)       Date:  2021-03-11       Impact factor: 2.713

7.  Recognition of Dimethylarginine Analogues by Tandem Tudor Domain Protein Spindlin1.

Authors:  Miriam R B Porzberg; Laust Moesgaard; Catrine Johansson; Udo Oppermann; Jacob Kongsted; Jasmin Mecinović
Journal:  Molecules       Date:  2022-02-01       Impact factor: 4.411

8.  Histidine methyltransferase SETD3 methylates structurally diverse histidine mimics in actin.

Authors:  Jordi C J Hintzen; Huida Ma; Hao Deng; Apolonia Witecka; Steffen B Andersen; Jakub Drozak; Hong Guo; Ping Qian; Haitao Li; Jasmin Mecinović
Journal:  Protein Sci       Date:  2022-05       Impact factor: 6.725
  8 in total

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