Literature DB >> 20095001

Monitoring the activity of 2-oxoglutarate dependent histone demethylases by NMR spectroscopy: direct observation of formaldehyde.

Richard J Hopkinson1, Refaat B Hamed, Nathan R Rose, Timothy D W Claridge, Christopher J Schofield.   

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Year:  2010        PMID： 20095001     DOI： 10.1002/cbic.200900713

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  17 in total

1.  Development of homogeneous luminescence assays for histone demethylase catalysis and binding.

Authors:  Akane Kawamura; Anthony Tumber; Nathan R Rose; Oliver N F King; Michelle Daniel; Udo Oppermann; Tom D Heightman; Christopher Schofield
Journal:  Anal Biochem       Date:  2010-05-21       Impact factor: 3.365

2.  Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase.

Authors:  Elena M Sánchez-Fernández; Hanna Tarhonskaya; Khalid Al-Qahtani; Richard J Hopkinson; James S O McCullagh; Christopher J Schofield; Emily Flashman
Journal:  Biochem J       Date:  2013-01-15       Impact factor: 3.857

3.  Reconstitution of nucleosome demethylation and catalytic properties of a Jumonji histone demethylase.

Authors:  Carrie Shiau; Michael J Trnka; Alen Bozicevic; Idelisse Ortiz Torres; Bassem Al-Sady; Alma L Burlingame; Geeta J Narlikar; Danica Galonić Fujimori
Journal:  Chem Biol       Date:  2013-04-18

4.  Inhibition of the histone demethylase JMJD2E by 3-substituted pyridine 2,4-dicarboxylates.

Authors:  Armin Thalhammer; Jasmin Mecinović; Christoph Loenarz; Anthony Tumber; Nathan R Rose; Tom D Heightman; Christopher J Schofield
Journal:  Org Biomol Chem       Date:  2010-11-15       Impact factor: 3.876

5.  Investigating d-lysine stereochemistry for epigenetic methylation, demethylation and recognition.

Authors:  Roman Belle; Abbas H K Al Temimi; Kiran Kumar; Bas J G E Pieters; Anthony Tumber; James E Dunford; Catrine Johansson; Udo Oppermann; Tom Brown; Christopher J Schofield; Richard J Hopkinson; Robert S Paton; Akane Kawamura; Jasmin Mecinović
Journal:  Chem Commun (Camb)       Date:  2017-12-12       Impact factor: 6.222

6.  Structural and stereoelectronic insights into oxygenase-catalyzed formation of ethylene from 2-oxoglutarate.

Authors:  Zhihong Zhang; Tristan J Smart; Hwanho Choi; Florence Hardy; Christopher T Lohans; Martine I Abboud; Melodie S W Richardson; Robert S Paton; Michael A McDonough; Christopher J Schofield
Journal:  Proc Natl Acad Sci U S A       Date:  2017-04-18       Impact factor: 11.205

7.  Human UTY(KDM6C) is a male-specific Nϵ-methyl lysyl demethylase.

Authors:  Louise J Walport; Richard J Hopkinson; Melanie Vollmar; Sarah K Madden; Carina Gileadi; Udo Oppermann; Christopher J Schofield; Catrine Johansson
Journal:  J Biol Chem       Date:  2014-05-05       Impact factor: 5.157

Review 8.  Targeting histone lysine demethylases - progress, challenges, and the future.

Authors:  Cyrille C Thinnes; Katherine S England; Akane Kawamura; Rasheduzzaman Chowdhury; Christopher J Schofield; Richard J Hopkinson
Journal:  Biochim Biophys Acta       Date:  2014-05-21

9.  Is JmjC oxygenase catalysis limited to demethylation?

Authors:  Richard J Hopkinson; Louise J Walport; Martin Münzel; Nathan R Rose; Tristan J Smart; Akane Kawamura; Timothy D W Claridge; Christopher J Schofield
Journal:  Angew Chem Int Ed Engl       Date:  2013-06-20       Impact factor: 15.336

10.  Non-enzymatic chemistry enables 2-hydroxyglutarate-mediated activation of 2-oxoglutarate oxygenases.

Authors:  Hanna Tarhonskaya; Anna M Rydzik; Ivanhoe K H Leung; Nikita D Loik; Mun Chiang Chan; Akane Kawamura; James S O McCullagh; Timothy D W Claridge; Emily Flashman; Christopher J Schofield
Journal:  Nat Commun       Date:  2014-03-05       Impact factor: 14.919
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