| Literature DB >> 29175649 |
Seyedeh Zahra Shahrokhi1, Faranak Kazerouni2, Firouzeh Ghaffari3.
Abstract
Anti-Müllerian hormone (AMH) is a homodimeric glycoprotein produced by granulosa cells of growing ovarian follicles. AMH appears to have an inhibitory effect on both primordial follicle recruitment and responsiveness of growing follicles to follicle-stimulating hormone (FSH). This hormone is considered to be a reliable marker of ovarian reserve; therefore, it is crucial to determine which factors influence AMH levels for prognostic and diagnostic purposes. In this review we intend to discuss the effect of genetic and environmental factors which may lead to AMH interindividual variability.Entities:
Keywords: Anti-Müllerian hormone; Environmental factors; Genetic factors; MTHFR polymorphism; Ovarian reserve; Vitamin D deficiency
Mesh:
Substances:
Year: 2017 PMID: 29175649 DOI: 10.1016/j.cca.2017.11.027
Source DB: PubMed Journal: Clin Chim Acta ISSN: 0009-8981 Impact factor: 3.786