Anne Caroline Oenning1,2, Benjamin Salmon1, Karla de Faria Vasconcelos2,3, Laura Ferreira Pinheiro Nicolielo3, Ivo Lambrichts4, Gerard Sanderink5, Ruben Pauwels3,6, Reinhilde Jacobs3,7. 1. 1 Department of Dental Medicine,Orofacial Pathologies Imaging and Biotherapies Lab, Paris Descartes University Sorbonne Paris Cité Bretonneau Hospital , Paris , France. 2. 2 Department of Oral Diagnosis,Division of Oral Radiology, Piracicaba Dental School, University of Campinas , Piracicaba, Sao Paulo , Brazil. 3. 3 Department of Imaging and Pathology,OMFS IMPATH research group, Catholic University of Leuven, University Hospitals Leuven , Leuven , Belgium. 4. 4 Department of Morphology, Biomedical Research Institute, University of Hasselt , Hasselt , Belgium. 5. 5 Department of Oral Radiology,Academic Center for Dentistry Amsterdam, University of Amsterdam and Vrije Universiteit , Amsterdam , Netherlands. 6. 6 Department of Radiology,Faculty of Dentistry, Chulalongkorn University , Bangkok , Thailand. 7. 8 Department of Dental Medicine,Karolinska Institutet , Stockholm , Sweden.
Abstract
OBJECTIVES: This report aims to describe the development of age-specific phantoms for use in paediatric dentomaxillofacial radiology research. These phantoms are denoted DIMITRA paediatric skull phantoms as these have been primarily developed and validated for the DIMITRA European research project (Dentomaxillofacial paediatric imaging: an investigation towards low-dose radiation induced risks). METHODS: To create the DIMITRA paediatric phantoms, six human paediatric skulls with estimated ages ranging between 4 and 10 years- old were selected, protected with non-radiopaque tape and immersed in melted Mix-D soft tissue equivalent material, by means of a careful procedure (layer-by-layer). Mandibles were immersed separately and a Mix-D tongue model was also created. For validation purposes, the resulting paediatric phantoms were scanned using a cone-beam CT unit with different exposure parameter settings. RESULTS: Preliminary images deriving from all scans were evaluated by two dentomaxillofacial radiologists, to check for air bubbles, artefacts and inhomogeneities of the Mix-D and a potential effect on the visualization of the jaw bone. Only skulls presenting perfect alignment of Mix-D surrounding the bone surfaces with adequate and realistic soft tissue thickness density were accepted. CONCLUSIONS: The DIMITRA anthropomorphic phantoms can yield clinically equivalent images for optimization studies in dentomaxillofacial research. In addition, the layer-by-layer technique proved to be practical and reproducible, as long as recommendations are carefully followed.
OBJECTIVES: This report aims to describe the development of age-specific phantoms for use in paediatric dentomaxillofacial radiology research. These phantoms are denoted DIMITRA paediatric skull phantoms as these have been primarily developed and validated for the DIMITRA European research project (Dentomaxillofacial paediatric imaging: an investigation towards low-dose radiation induced risks). METHODS: To create the DIMITRA paediatric phantoms, six human paediatric skulls with estimated ages ranging between 4 and 10 years- old were selected, protected with non-radiopaque tape and immersed in melted Mix-D soft tissue equivalent material, by means of a careful procedure (layer-by-layer). Mandibles were immersed separately and a Mix-D tongue model was also created. For validation purposes, the resulting paediatric phantoms were scanned using a cone-beam CT unit with different exposure parameter settings. RESULTS: Preliminary images deriving from all scans were evaluated by two dentomaxillofacial radiologists, to check for air bubbles, artefacts and inhomogeneities of the Mix-D and a potential effect on the visualization of the jaw bone. Only skulls presenting perfect alignment of Mix-D surrounding the bone surfaces with adequate and realistic soft tissue thickness density were accepted. CONCLUSIONS: The DIMITRA anthropomorphic phantoms can yield clinically equivalent images for optimization studies in dentomaxillofacial research. In addition, the layer-by-layer technique proved to be practical and reproducible, as long as recommendations are carefully followed.
Authors: Matheus L Oliveira; Guilherme M Tosoni; David H Lindsey; Kristopher Mendoza; Sotirios Tetradis; Sanjay M Mallya Journal: Oral Surg Oral Med Oral Pathol Oral Radiol Date: 2013-04
Authors: C F Hildebolt; R C Rupich; M W Vannier; D J Zerbolio; M K Shrout; S Cohen; A Pinkas Journal: J Clin Periodontol Date: 1993-11 Impact factor: 8.728
Authors: Laura Ferreira Pinheiro Nicolielo; Jeroen Van Dessel; G Harry van Lenthe; Ivo Lambrichts; Reinhilde Jacobs Journal: Br J Radiol Date: 2018-09-17 Impact factor: 3.039
Authors: Anne Caroline Oenning; Ruben Pauwels; Andreas Stratis; Karla De Faria Vasconcelos; Elisabeth Tijskens; Annelore De Grauwe; Reinhilde Jacobs; Benjamin Salmon Journal: Sci Rep Date: 2019-04-02 Impact factor: 4.379