Literature DB >> 29161245

Cancer systems biology: Harnessing off-target effects.

Gaye Saginc1, Franziska Voellmy1,2, Rune Linding1.   

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Year:  2017        PMID： 29161245     DOI： 10.1038/nchembio.2519

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  10 in total

Review 1.  The influence of drug-like concepts on decision-making in medicinal chemistry.

Authors:  Paul D Leeson; Brian Springthorpe
Journal:  Nat Rev Drug Discov       Date:  2007-11       Impact factor: 84.694

Review 2.  Network pharmacology: the next paradigm in drug discovery.

Authors:  Andrew L Hopkins
Journal:  Nat Chem Biol       Date:  2008-11       Impact factor: 15.040

Review 3.  Personalized network-based treatments in oncology.

Authors:  X Robin; P Creixell; O Radetskaya; C C Santini; J Longden; R Linding
Journal:  Clin Pharmacol Ther       Date:  2013-08-29       Impact factor: 6.875

Review 4.  Timeline: Chemotherapy and the war on cancer.

Authors:  Bruce A Chabner; Thomas G Roberts
Journal:  Nat Rev Cancer       Date:  2005-01       Impact factor: 60.716

Review 5.  Drugging the 'undruggable' cancer targets.

Authors:  Chi V Dang; E Premkumar Reddy; Kevan M Shokat; Laura Soucek
Journal:  Nat Rev Cancer       Date:  2017-06-23       Impact factor: 60.716

6.  Polypharmacology-based ceritinib repurposing using integrated functional proteomics.

Authors:  Brent M Kuenzi; Lily L Remsing Rix; Paul A Stewart; Bin Fang; Fumi Kinose; Annamarie T Bryant; Theresa A Boyle; John M Koomen; Eric B Haura; Uwe Rix
Journal:  Nat Chem Biol       Date:  2017-10-09       Impact factor: 15.040

7.  Comparative Efficacy of Ceritinib and Crizotinib as Initial ALK-Targeted Therapies in Previously Treated Advanced NSCLC: An Adjusted Comparison with External Controls.

Authors:  Daniel Shao-Weng Tan; António Araújo; Jie Zhang; James Signorovitch; Zheng-Yi Zhou; Xiaopeng Cai; Geoffrey Liu
Journal:  J Thorac Oncol       Date:  2016-06-08       Impact factor: 15.609

Review 8.  Recent advances of cocktail chemotherapy by combination drug delivery systems.

Authors:  Quanyin Hu; Wujin Sun; Chao Wang; Zhen Gu
Journal:  Adv Drug Deliv Rev       Date:  2015-11-06       Impact factor: 15.470

Review 9.  The multistep nature of cancer.

Authors:  B Vogelstein; K W Kinzler
Journal:  Trends Genet       Date:  1993-04       Impact factor: 11.639

10.  Rationale for co-targeting IGF-1R and ALK in ALK fusion-positive lung cancer.

Authors:  Christine M Lovly; Nerina T McDonald; Heidi Chen; Sandra Ortiz-Cuaran; Lukas C Heukamp; Yingjun Yan; Alexandra Florin; Luka Ozretić; Diana Lim; Lu Wang; Zhao Chen; Xi Chen; Pengcheng Lu; Paul K Paik; Ronglai Shen; Hailing Jin; Reinhard Buettner; Sascha Ansén; Sven Perner; Michael Brockmann; Marc Bos; Jürgen Wolf; Masyar Gardizi; Gavin M Wright; Benjamin Solomon; Prudence A Russell; Toni-Maree Rogers; Yoshiyuki Suehara; Monica Red-Brewer; Rudy Tieu; Elisa de Stanchina; Qingguo Wang; Zhongming Zhao; David H Johnson; Leora Horn; Kwok-Kin Wong; Roman K Thomas; Marc Ladanyi; William Pao
Journal:  Nat Med       Date:  2014-08-31       Impact factor: 53.440
  10 in total
  3 in total

1.  A Middle-Out Modeling Strategy to Extend a Colon Cancer Logical Model Improves Drug Synergy Predictions in Epithelial-Derived Cancer Cell Lines.

Authors:  Eirini Tsirvouli; Vasundra Touré; Barbara Niederdorfer; Miguel Vázquez; Åsmund Flobak; Martin Kuiper
Journal:  Front Mol Biosci       Date:  2020-10-09

Review 2.  Marine Natural Products in Clinical Use.

Authors:  Neshatul Haque; Sana Parveen; Tingting Tang; Jiaen Wei; Zunnan Huang
Journal:  Mar Drugs       Date:  2022-08-18       Impact factor: 6.085

3.  A pH-Induced Reversible Assembly System with Resveratrol-Controllable Loading and Release for Enhanced Tumor-Targeting Chemotherapy.

Authors:  Qingkai Zheng; Wenjing Cheng; Xiaoping Zhang; Runxia Shao; Zhongdong Li
Journal:  Nanoscale Res Lett       Date:  2019-09-06       Impact factor: 4.703
  3 in total

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