Literature DB >> 23995267

Personalized network-based treatments in oncology.

X Robin1, P Creixell, O Radetskaya, C C Santini, J Longden, R Linding.   

Abstract

Network medicine aims at unraveling cell signaling networks to propose personalized treatments for patients suffering from complex diseases. In this short review, we show the relevance of network medicine to cancer treatment by outlining the potential convergence points of the most recent technological and scientific developments in both drug design and signaling network analysis.

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Year:  2013        PMID： 23995267     DOI： 10.1038/clpt.2013.171

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


  6 in total

1.  Cancer systems biology: Harnessing off-target effects.

Authors:  Gaye Saginc; Franziska Voellmy; Rune Linding
Journal:  Nat Chem Biol       Date:  2017-11-21       Impact factor: 15.040

Review 2.  Protein engineering: a new frontier for biological therapeutics.

Authors:  Peter H Tobin; David H Richards; Randolph A Callender; Corey J Wilson
Journal:  Curr Drug Metab       Date:  2014       Impact factor: 3.731

Review 3.  The crucial role of protein phosphorylation in cell signaling and its use as targeted therapy (Review).

Authors:  Fatima Ardito; Michele Giuliani; Donatella Perrone; Giuseppe Troiano; Lorenzo Lo Muzio
Journal:  Int J Mol Med       Date:  2017-06-22       Impact factor: 4.101

4.  Decoding cancer heterogeneity: studying patient-specific signaling signatures towards personalized cancer therapy.

Authors:  Efrat Flashner-Abramson; Swetha Vasudevan; Ibukun Adesoji Adejumobi; Amir Sonnenblick; Nataly Kravchenko-Balasha
Journal:  Theranostics       Date:  2019-07-09       Impact factor: 11.556

5.  Overcoming resistance to BRAFV600E inhibition in melanoma by deciphering and targeting personalized protein network alterations.

Authors:  S Vasudevan; E Flashner-Abramson; Heba Alkhatib; Sangita Roy Chowdhury; I A Adejumobi; D Vilenski; S Stefansky; A M Rubinstein; N Kravchenko-Balasha
Journal:  NPJ Precis Oncol       Date:  2021-06-10

6.  Functional Analysis and Characterization of Differential Coexpression Networks.

Authors:  Chia-Lang Hsu; Hsueh-Fen Juan; Hsuan-Cheng Huang
Journal:  Sci Rep       Date:  2015-08-18       Impact factor: 4.379
  6 in total

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