Literature DB >> 2911747

Direct observation of native DNA structures with the scanning tunneling microscope.

T P Beebe1, T E Wilson, D F Ogletree, J E Katz, R Balhorn, M B Salmeron, W J Siekhaus.   

Abstract

Uncoated double-stranded DNA dissolved in a salt solution was deposited on graphite and imaged in air with the scanning tunneling microscope (STM). The resolution was such that the major and minor grooves could be distinguished. The pitch of the helix varied between 27 and 63 angstroms in the images obtained. Thus the STM can be useful for structural studies of a variety of uncoated and isolated biomolecules.

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Year:  1989        PMID： 2911747     DOI： 10.1126/science.2911747

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  12 in total

1.  Immobilization of DNA for scanning probe microscopy.

Authors:  D P Allison; L A Bottomley; T Thundat; G M Brown; R P Woychik; J J Schrick; K B Jacobson; R J Warmack
Journal:  Proc Natl Acad Sci U S A       Date:  1992-11-01       Impact factor: 11.205

2.  Potentiostatic deposition of DNA for scanning probe microscopy.

Authors:  S M Lindsay; N J Tao; J A DeRose; P I Oden; R E Harrington; L Shlyakhtenko
Journal:  Biophys J       Date:  1992-06       Impact factor: 4.033

3.  DNA sequencing by hybridization: 100 bases read by a non-gel-based method.

Authors:  Z Strezoska; T Paunesku; D Radosavljević; I Labat; R Drmanac; R Crkvenjakov
Journal:  Proc Natl Acad Sci U S A       Date:  1991-11-15       Impact factor: 11.205

4.  Imaging of single uncoated DNA molecules by scanning tunneling microscopy.

Authors:  D Keller; C Bustamante; R W Keller
Journal:  Proc Natl Acad Sci U S A       Date:  1989-07       Impact factor: 11.205

5.  Visualization of DNA and protein-DNA complexes with atomic force microscopy.

Authors:  Yuri L Lyubchenko; Alexander A Gall; Luda S Shlyakhtenko
Journal:  Methods Mol Biol       Date:  2014

6.  Structure of hydrated oligonucleotides studied by in situ scanning tunneling microscopy.

Authors:  T W Jing; A M Jeffrey; J A DeRose; Y L Lyubchenko; L S Shlyakhtenko; R E Harrington; E Appella; J Larsen; A Vaught; D Rekesh
Journal:  Proc Natl Acad Sci U S A       Date:  1993-10-01       Impact factor: 11.205

7.  Identification of DNA--cisplatin adducts in a blind trial of in situ scanning tunneling microscopy.

Authors:  A M Jeffrey; T W Jing; J A DeRose; A Vaught; D Rekesh; F X Lu; S M Lindsay
Journal:  Nucleic Acids Res       Date:  1993-12-25       Impact factor: 16.971

8.  Masking generates contiguous segments of metal-coated and bare DNA for scanning tunneling microscope imaging.

Authors:  D D Dunlap; R García; E Schabtach; C Bustamante
Journal:  Proc Natl Acad Sci U S A       Date:  1993-08-15       Impact factor: 11.205

9.  Scanning tunneling microscopy of a wheat seed storage protein reveals details of an unusual supersecondary structure.

Authors:  M J Miles; H J Carr; T C McMaster; K J I'Anson; P S Belton; V J Morris; J M Field; P R Shewry; A S Tatham
Journal:  Proc Natl Acad Sci U S A       Date:  1991-01-01       Impact factor: 11.205

10.  Transverse tunneling through DNA hydrogen bonded to an electrode.

Authors:  Jin He; Lisha Lin; Peiming Zhang; Quinn Spadola; Zhiqun Xi; Qiang Fu; Stuart Lindsay
Journal:  Nano Lett       Date:  2008-07-29       Impact factor: 11.189
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